Effects of Aging and Smoking Duration on Cigarette Smoke-Induced COPD Severity

Kim, Eun Jung; Yoon, Seok Jun; Kim, Young Eun; Go, Dun-Sol; Jung, Yoon-Sun

doi:10.3346/jkms.2019.34.e90

Cited by 22 publications

(18 citation statements)

References 22 publications

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“…It could be caused by the following reason. COPD was an age-related condition, and several evidences suggested a relationship with a rapidly increasing aging [14,15]. It seems like older patients are more likely to develop subtle cognitive deficits [16].…”

Section: Discussionmentioning

confidence: 99%

Quality analysis of discharge instruction among 602 hospitalized patients in China: a multicenter, cross-sectional study

Yang

Liang

Zhao

et al. 2020

BMC Health Serv Res

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Background: The aim of this study was to understand the quality of discharge guidance for patients with chronic diseases, to clarify the gap between patient needs and the content of discharge guidance, and to provide a reference for health education and clinical path management of patients with chronic diseases in the future. Methods: A total of 602 inpatients with stroke, coronary heart disease, cancer, chronic obstructive pulmonary disease and diabetes from the chronic disease-related departments of 7 tertiary general hospitals in China were selected by convenience sampling. Measures included a demographic questionnaire and the Quality of Discharged Teaching Scale(QDTS). Descriptive analysis ANOVA and paired t-test were completed by SPSS 22.0 software. Results: The overall average score of QDTS in this survey was 155.79 ± 23.29. The total score of QDTS in chronic obstructive pulmonary disease was lower than coronary heart disease (P < 0.001) and cancer (P = 0.02). While coronary heart disease was higher than stroke (P = 0.01) and diabetes (P = 0.01). And the scores of patients on discharge guidance skills and effects were higher than 8.50. Conclusions: The level of the patients' perception of quality of discharge insrtuction is middle to high. Managers should understand the characteristics of various departments, give corresponding guidance and help, and clinical nurses should understand the characteristics of ward patients and pay more attention to individual guidance.

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Section: Discussionmentioning

confidence: 99%

Quality analysis of discharge instruction among 602 hospitalized patients in China: a multicenter, cross-sectional study

Yang

Liang

Zhao

et al. 2020

BMC Health Serv Res

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“…While over 97 independent genetic associations with lung parameters defining COPD and with COPD risk have been described, 12 cigarette smoking is by far the main environmental risk factor for COPD. Hence, between 15% and 50% of smokers develop COPD, whereas 80 to 90% of COPD patients are smokers or ex‐smokers 13,14 . To date, no definitive evidence on whether ever‐smokers is at an increased risk of COVID‐19.…”

Section: The Influence Of Copd Risk Factors On Covid‐19mentioning

confidence: 99%

COVID‐19 Susceptibility in chronic obstructive pulmonary disease

Olloquequi

2020

Eur J Clin Investigation

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In the middle of December 2019, Chinese health authorities detected a series of pneumonia cases caused by an unknown agent in Wuhan, the capital of Hubei province. The causative agent was soon identified as a new strain of human-infecting coronavirus, 1 firstly named 2019 novel coronavirus (2019-nCoV) and later renamed as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The infection disease caused by SARS-CoV-2, known as coronavirus disease 2019 (COVID-19), varied from asymptomatic or common cold-like symptoms such as dry cough, fever and tiredness to severe dyspnoea and respiratory failure. 2 This initial outbreak alarmingly spread through China and other countries, and barely three months later, the World Health Organization (WHO) formally declared COVID-19 a global pandemic. 3

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“…11 COPD is an age-related disorder, and several evidences suggested a relationship with a rapidly increasing age. 12,13 The mean patient age was 61.46±10.57 years and 56.7% of patients were above 60 years of age. This distribution can be explained by the physiological decrease in FEV1 with age where the slope becomes steeper when aggravated by risk factors, particularly smoking.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness and tolerability of formoterol plus glycopyrronium combination in patients with chronic obstructive pulmonary disease: FINE registry

Gopal¹,

Garde

et al. 2020

Int J Adv Med

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Background: Long-term therapy for chronic obstructive pulmonary disease (COPD) is progressing fast. Dual bronchodilation with long-acting muscarinic antagonist (LAMA) and long-acting β2-agonist (LABA) fixed dose combinations (FDC) have been available over the past few years. To evaluate the real-world tolerability and effectiveness of formoterol plus glycopyrronium FDC inhaler, a post-marketing surveillance study was conducted in Indian population.Methods: This was an open-label, observational registry in which COPD patients, who were prescribed forglyn (a brand of FDC of glycopyrronium 25 mcg and formoterol fumarate dihydrate 6 mcg dry powder inhalation). The effectiveness, safety and tolerability of this LAMA/LABA combination were evaluated for 4, 8 and 12 weeks. The safety and tolerability was assessed based on the incidence of adverse events (AEs). Effectiveness was evaluated based on change in total symptom score from baseline to end of 12 weeks. The forced expiratory volume in 1 second (FEV1) was performed at baseline and end of 12 weeks.Results: Total COPD patients enrolled were 605, of which 78.5% were males and 21.5% were females. Patients showing improvement of symptoms at week 4 were 587 (97.02%).Overall, at the end of 8 week and 12 week 98.34 % and 99.49% patients showed improvement in the total symptoms respectively. About 0.49% did not show any improvement. AEs were reported in 64 (10.64%) patients with no serious AEs. Mean FEV1 of 476 patients before treatment was 1.53±0.68 L at baseline which changed to 1.85±4.74 L at the end of 12 weeks, with was statistically significant (p<0.05).Conclusions: In real-life clinical practice in India, formoterol and glycopyrronium FDC dry powder inhaler was well tolerated in COPD patients, and can be regarded as an effective option for maintenance treatment.

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Effects of Aging and Smoking Duration on Cigarette Smoke-Induced COPD Severity

Cited by 22 publications

References 22 publications

Quality analysis of discharge instruction among 602 hospitalized patients in China: a multicenter, cross-sectional study

Quality analysis of discharge instruction among 602 hospitalized patients in China: a multicenter, cross-sectional study

COVID‐19 Susceptibility in chronic obstructive pulmonary disease

Effectiveness and tolerability of formoterol plus glycopyrronium combination in patients with chronic obstructive pulmonary disease: FINE registry

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