Effects of age and gender on the baseline and 2 Gy 60 Co γ-ray-induced nucleoplasmic bridges frequencies in the peripheral blood lymphocytes of Chinese population

Cai, Tian-Jing; Lü, Xue; Tian, Xue-Lei; Hua, Zhao; Li, Shuang; Jiao, Feng; Chen, Deqing; Tian, Mei; Liu, Qingjie

doi:10.1016/j.mrgentox.2018.06.013

Cited by 10 publications

(1 citation statement)

References 54 publications

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“…The impact of sexual orientation could not be viewed as pertinent because of the modest number of female members [32]. In contrast, Cai et al [33] confirmed that the gender of subjects influences the radiation-prompted levels of NPB and MN. Furthermore, the impact of age on the incited NPB levels demonstrated no specific example and should have been additionally researched [33].…”

Section: Table III Poisson Regression Analysis Of Gender and Age On T...mentioning

confidence: 99%

The Evaluation of Frequencies of Cytogenetic Biomarkers in Lymphocyte of Residents from High Natural Radiation Area in West Sulawesi, Indonesia

Syaifudin¹,

Ramadhani²,

Purnami³

et al. 2022

International Journal on Advanced Science, Engineering and Information Technology

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Residents living in high natural radiation areas may pose health consequences such as cancer. The study aims to evaluate the frequencies of cytogenetic biomarkers covering micronuclei (MN), nucleoplasmic bridge (NPB), and nuclear bud (NBUD) with the cytokinesis-block micronucleus (CBMN) assay. This cross-sectional study was done on 51 blood lymphocytes from the resident of Mamuju, West Sulawesi, Indonesia that was done according to standard procedure. After being stained with Giemsa solution, these biomarkers were observed on about 1,000 binucleated cells. The results showed a low frequency of MN (0.0162 in 36,091 cells) and extremely low frequencies of other biomarkers (0.00019 and 0.00061 for NPB and NBUD, respectively) in the study area, whereas these were 0.0225 MNs in 15,000 cells, and 0.00013 and 0.00120 for NPB and NBUD, respectively, in the control area. MNs and NBUDs were lower in the study area compared to control. No statistically significant differences (p>0.05) in NPB were found between the two areas, but not for NBUD. The frequencies of MN and NPB in female is higher than that of male in both areas. In the control group, males experienced a decrease in the number of NPB to 0.7 times compared to females, and every extra one year of age, 1.047 times more NBUDs were found. None of the confounding factors was influenced in the study group. It was concluded that there is no impact of high natural radiation to the local residents based on cytogenetics evaluation, with a note that further studies on a higher number of samples and other relevant biomarkers are required.

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Section: Table III Poisson Regression Analysis Of Gender and Age On T...mentioning

confidence: 99%

The Evaluation of Frequencies of Cytogenetic Biomarkers in Lymphocyte of Residents from High Natural Radiation Area in West Sulawesi, Indonesia

Syaifudin¹,

Ramadhani²,

Purnami³

et al. 2022

International Journal on Advanced Science, Engineering and Information Technology

View full text Add to dashboard Cite

show abstract

Effects of radiation quality and dose rate on radiation-induced nucleoplasmic bridges in human peripheral blood lymphocytes

Hua

Cai

Lü

et al. 2021

Mutation Research/Genetic Toxicology and Environmental Mutagene

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Cytogenetic monitoring of peripheral blood lymphocytes from medical radiation professionals occupationally exposed to low-dose ionizing radiation

Tian

Lü

Cai

et al. 2021

Mutation Research/Genetic Toxicology and Environmental Mutagene

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Effects of age and gender on the baseline and 2 Gy 60 Co γ-ray-induced nucleoplasmic bridges frequencies in the peripheral blood lymphocytes of Chinese population

Cited by 10 publications

References 54 publications

The Evaluation of Frequencies of Cytogenetic Biomarkers in Lymphocyte of Residents from High Natural Radiation Area in West Sulawesi, Indonesia

The Evaluation of Frequencies of Cytogenetic Biomarkers in Lymphocyte of Residents from High Natural Radiation Area in West Sulawesi, Indonesia

Effects of radiation quality and dose rate on radiation-induced nucleoplasmic bridges in human peripheral blood lymphocytes

Cytogenetic monitoring of peripheral blood lymphocytes from medical radiation professionals occupationally exposed to low-dose ionizing radiation

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