Effects of aerospace environments on the cardiovascular system

Ercan, Erdinç

doi:10.5152/anatoljcardiol.2021.s103

Cited by 18 publications

(15 citation statements)

References 1 publication

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“…For example, in hypobaric and hypoxic contexts where flight and space activities take place, blood in the circulatory system is directed to the brain and the heart-increasing fluid distribution complications-and as partial pressure of O2 decreases, it causes the heart rate to accelerate. Thus tachycardia can develop, while stroke volume does not change 10 . Concentrating on arrhythmia, another potential pathophysiological pathway in space flight is through cosmic radiation exposure, which can cause inflammation and decrease in microvascular density 11 .…”

Section: Health Degradationmentioning

confidence: 99%

Machine-Learning Workflow for Edge Computed Arrhythmia Detection in Exploration-Class Missions

Mani,

Paul,

Archambault

et al. 2023

Preprint

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Deep-space missions require preventative care methods based on predictive models for identifying in-space pathologies. Deploying such models requires flexible edge computing, which Open Neural Network Exchange (ONNX) formats enable by optimizing inference directly on wearable edge devices. This work demonstrates an innovative approach to point-of-care machine learning model pipelines by combining this capacity with an advanced self-optimizing training scheme to classify periods of Normal Sinus Rhythm (NSR), Atrial Fibrillation (AFIB) and Atrial Flutter (AFL). 742 hours of electrocardiogram (ECG) recordings were pre-processed into 30-second normalized samples where variable mode decomposition purged muscle artifacts and instrumentation noise. Seventeen heart rate variability and morphological ECG features were extracted by convoluting peak detection with Gaussian distributions and delineating QRS complexes using discrete wavelet transforms. The decision tree classifier’s features, parameters and hyperparameters were self-optimized through stratified triple nested cross-validation ranked on F1-scoring against cardiologist labelling. The selected model achieved a macro F1-score of 0.899 with 0.993 for NSR, 0.938 for AFIB and 0.767 for AFL. The most important features included median P-wave amplitudes, PNN20, and mean heart rates. The ONNX-translated pipeline took 9.2 s/sample. The novel combination of our self-optimizing scheme and deployment use case of ONNX demonstrated overall accurate operational tachycardia detection.

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Section: Health Degradationmentioning

confidence: 99%

Machine-Learning Workflow for Edge Computed Arrhythmia Detection in Exploration-Class Missions

Mani,

Paul,

Archambault

et al. 2023

Preprint

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“…Pilot dengan hipertensi terkontrol baik tanpa tanda kerusakan organ diperbolehkan untuk terbang. 10 Hipertensi Pulmonal Pada pasien hipertensi pulmonal, lingkungan hipobarik selama perjalanan udara menyebabkan vasokonstriksi hipoksia umum dalam sirkulasi paru, berpotensi memperburuk resistensi pembuluh darah paru dan afterload ventrikel kanan serta dapat menyebabkan gagal jantung kanan akut. 14 Perjalanan udara dapat menyebabkan masalah pernapasan yang signifikan pada pasien hipertensi arteri pulmonal berat karena hipoksemia di ketinggian.…”

Section: Pendahuluanunclassified

Perjalanan Udara pada Penderita Penyakit Jantung: Amankah?

Koswara¹,

Yap

Chandra

et al. 2023

Cermin Dunia Kedokteran

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Perubahan tekanan, suhu, tingkat kelembapan, keadaan imobilisasi, suara bising, turbulensi, dan ekspansi udara di rongga tubuh yang berkaitan dengan perjalanan via udara dapat berdampak pada tubuh manusia. Para penumpang dengan riwayat penyakit jantung harus menyadari risikonya dan melakukan tindakan pencegahan. Changes in pressure, temperature, humidity levels, immobilization, noise, turbulence, and expansion of air in the body cavity associated with air travel can all have an impact on the human body. Passengers with a history of heart disease must be aware of the risks and take the necessary precautions.

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Section: Clinical Studies Across the World That Reported The Effect O...mentioning

confidence: 99%

“…The effect of altitude on people with established chronic kidney disease oxygen which might lead to acute hypobaric hypoxia (43). This state will cause a redistribution of the blood to the main organs, the heart and the brain, inducing tachycardia and a decrease of the kidney perfusion as well as peripheral cyanosis (43). This is different from another entity called decompression sickness which is secondary to the formation of nitrogen bubbles in tissues and blood when exposed to an acute decrease in environmental pressure (43).…”

Section: Clinical Studies Across the World That Reported The Effect O...mentioning

confidence: 99%

Where do you live and what do you do? Two questions that might impact your kidney health

Aoun¹,

Chelala²

2022

Front. Nephrol.

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In many cases the social determinants of health need to be assessed through their interaction with environmental factors. This review looks at the impact of physical location and occupation of individuals on their kidney health. It examines the effect of living at high altitude on kidney function and the relationship between extreme cold or hot temperatures and the incidence of kidney injury. It reviews as well the many occupations that have been linked to kidney disease in high-income and low-and-middle-income countries. As a conclusion, this overview proposes preventive recommendations that could be individualized based on weather, altitude, socio-economic level of the country and occupation of the individual.

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Effects of aerospace environments on the cardiovascular system

Cited by 18 publications

References 1 publication

Machine-Learning Workflow for Edge Computed Arrhythmia Detection in Exploration-Class Missions

Machine-Learning Workflow for Edge Computed Arrhythmia Detection in Exploration-Class Missions

Perjalanan Udara pada Penderita Penyakit Jantung: Amankah?

Where do you live and what do you do? Two questions that might impact your kidney health

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