Effects of aerobic physical exercise in the elderly with type 2 diabetes mellitus

Tessier, Daniel; Ménard, Julie; Fülöp, Tamás; Ardilouze, Jean-Luc; Roy, Marie-Andrée; Dubuc, Nicole; Dubois, Marie‐France; Gauthier, Pierre

doi:10.1016/s0167-4943(00)00076-5

Cited by 130 publications

(136 citation statements)

References 36 publications

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“…In contrast, in the eight comparisons with exercise intensities less than or equal to 70% of VO 2max there was a much smaller 9.5% (range: 2.6%-18.4%) increase in VO 2max in the exercise group (post intervention standardized mean difference =0.40 SD, p=0.003). A sensitivity analysis revealed no differences between the trials that measured VO 2max directly [18,20,21,24] and those that calculated VO 2max according to validated equations [19,22,23].…”

Section: Resultsmentioning

confidence: 95%

“…All of the trials were randomized controlled trials, none of the trials was double blinded or had adequate allocation concealment. Five trials had adequately described dropouts [18,19,22,23,24], there were no dropouts in one of the studies [20], and one of the studies did not comment on dropouts [21]. The compliance to the exercise interventions was relatively high.…”

Section: Resultsmentioning

confidence: 99%

“…The compliance to the exercise interventions was relatively high. In four studies [18,19,22,24] the mean participation rate was above 90%, one article [23] simply indicated that compliance was good and one study did not comment on compliance [20]. In one study [21], compliance was relatively low.…”

Section: Resultsmentioning

confidence: 99%

“…The exercise interventions included The intensity of aerobic exercise was moderate in most studies and typically consisted of walking or cycling. One study added light resistance training with elastic bands (TheraBand) to their aerobic training program [19]. As expected, most studies did not describe having specific criteria, such as the ACSM criteria [61], to establish a true VO 2max .…”

Section: Resultsmentioning

confidence: 99%

“…Unfortunately previous randomized control trials that have measured the effects of structured exercise training on VO 2max in adults with Type 2 diabetes have had small sample sizes and have led to variable results [18,19,20,21,22,23,24]. Therefore, the main objective of this study is to use the meta-analysis procedure to systematically review the effects of exercise training on VO 2max .…”

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Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus

et al. 2003

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Aims/hypothesis. Low cardiorespiratory fitness is a powerful and independent predictor of mortality in people with diabetes. Several studies have examined the effects of exercise on cardiorespiratory fitness in Type 2 diabetic individuals. However, these studies had relatively small sample sizes and highly variable results. Therefore the aim of this study was to systematically review and quantify the effects of exercise on cardiorespiratory fitness in Type 2 diabetic individuals. Methods. MEDLINE, EMBASE, and four other databases were searched up to March 2002 for randomized, controlled trials evaluating effects of structured aerobic exercise interventions of 8 weeks or more on cardiorespiratory fitness in adults with Type 2 diabetes. Cardiorespiratory fitness was defined as maximal oxygen uptake (VO 2max ) during a maximal exercise test.Results. Seven studies, presenting data for nine randomized trials comparing exercise and control groups (overall n=266), met the inclusion criteria. Mean exercise characteristics were as follows: 3.4 sessions per week, 49 min per session for 20 weeks. Exercise intensity ranged from 50% to 75% of VO 2max . There was an 11.8% increase in VO 2max in the exercise group and a 1.0% decrease in the control group (post intervention standardized mean difference =0.53, p<0.003). Studies with higher exercise intensities tended to produce larger improvements in VO 2max . Exercise intensity predicted post-intervention weighted mean difference in HbA 1c (r=−0.91, p=0.002 Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus N. G. Boulé 1 , G. P. Kenny 1 , E. Haddad 2 , G. A. Wells 3, 4 , R. J. Sigal 1, 3 1 School of Human Kinetics, University of Ottawa, Ottawa, Ontario, Canada 2 Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada 3 Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada 4 Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada pacities of athletes. In recent decades, VO 2max has had a growing importance in clinical settings and has become the gold standard measure of cardiovascular fitness and exercise capacity [1]. There is evidence from large cohort studies that low cardiorespiratory fitness is a powerful and independent predictor of long-term cardiac mortality in people with diabetes [2,3,4], even after controlling for traditional risk factors such as age, hypercholesterolaemia, smoking, and hypertension and excluding individuals with evidence of coronary ischaemia during testing. Furthermore, in non-diabetic subjects undergoing repeated maximalThe maximal amount of oxygen consumed during exercise (VO 2max ) has been used for decades by exercise physiologists to determine the maximum exercise ca-

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Section: Resultsmentioning

confidence: 95%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

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Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus

et al. 2003

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Physical Activity Advice Only or Structured Exercise Training and Association With HbA_1cLevels in Type 2 Diabetes

Umpierre

Ribeiro²,

Kramer³

et al. 2011

JAMA

1,060

750

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Structured exercise training that consists of aerobic exercise, resistance training, or both combined is associated with HbA(1c) reduction in patients with type 2 diabetes. Structured exercise training of more than 150 minutes per week is associated with greater HbA(1c) declines than that of 150 minutes or less per week. Physical activity advice is associated with lower HbA(1c), but only when combined with dietary advice.

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Effects of Exercise on Glycemic Control and Body Mass in Type 2 Diabetes Mellitus

Boulé¹,

Haddad

Kenny

et al. 2001

JAMA

1,486

435

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Effects of aerobic physical exercise in the elderly with type 2 diabetes mellitus

Cited by 130 publications

References 36 publications

Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus

Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus

Physical Activity Advice Only or Structured Exercise Training and Association With HbA_1cLevels in Type 2 Diabetes

Effects of Exercise on Glycemic Control and Body Mass in Type 2 Diabetes Mellitus

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Effects of aerobic physical exercise in the elderly with type 2 diabetes mellitus

Cited by 130 publications

References 36 publications

Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus

Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus

Physical Activity Advice Only or Structured Exercise Training and Association With HbA1cLevels in Type 2 Diabetes

Effects of Exercise on Glycemic Control and Body Mass in Type 2 Diabetes Mellitus

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Physical Activity Advice Only or Structured Exercise Training and Association With HbA_1cLevels in Type 2 Diabetes