Effects of Aerobic Exercise on Uric Acid, Total Antioxidant Activity, Oxidative Stress, and Nitric Oxide in Human Saliva

González, D.; Marquina, Ramón; Rondón, Norelis; Rodrı́guez-Malaver, Antonio J.; Reyes, Rafael

doi:10.1080/15438620802103700

Cited by 53 publications

(72 citation statements)

References 42 publications

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“…Saliva samples were collected before and 5 min after the RAST as suggested by several papers [11][12][13]. After being collected, the samples were transported on ice to the laboratory and centrifuged at 3,000 × g for 10 min at 4°C.…”

Section: Collection Of Salivamentioning

confidence: 99%

Anaerobic exercise affects the saliva antioxidant/oxidant balance in high-performance pentathlon athletes

Sant’Anna¹,

Casimiro-Lopes²,

Boaventura³

et al. 2018

Hum Mov.

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Purpose. Investigate free radical production and antioxidant buffering in military pentathletes' saliva after their performance of a standardized, running-based anaerobic sprint test (RAST). Methods. Seven members of the Brazilian Navy pentathlon team were recruited to perform a running-based anaerobic test (~90 sec). The participants provided samples of saliva before and after the test that were analyzed for biomarkers of oxidative stress such as lipid peroxidation, total antioxidant capacity and the quantity of two specific antioxidants, glutathione and uric acid. Results. The lipid peroxidation increased ~2 fold after RAST, despite an increase in total antioxidant capacity (46%). The concentration of reduced glutathione did not change, while the uric acid concentration increased by 65%. Conclusions. The evaluation in saliva following a sprint test that lasted no more than 90 sec was sensitive enough to reveal changes in redox state.

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Section: Collection Of Salivamentioning

confidence: 99%

Anaerobic exercise affects the saliva antioxidant/oxidant balance in high-performance pentathlon athletes

Sant’Anna¹,

Casimiro-Lopes²,

Boaventura³

et al. 2018

Hum Mov.

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“…Similarly, Ajmani et al (2003) stated that maximal running exercise increased LOOH level significantly. On the other hand, González et al (2008) reported that the Table 2. Changes in LOOH, LDH, GPx and CAT levels in the control and training groups before and after exhaustive exercise in the pre-and post-training periods.…”

Section: Discussionmentioning

confidence: 99%

Effects of endurance training on exhaustive exercise-induced oxidative stress markers

Revan¹,

Erol²

2011

Afr. J. Pharm. Pharmacol.

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This study was aimed to investigate the effects of endurance training on lipid peroxidation and antioxidant enzyme levels in young adults. Twenty four male students participated in this study. Subjects were divided into two groups as training group (n=12) and control group (n=12). Subjects in the training groups performed running exercise 25 to 60 min/day, three days/week for eight weeks at an intensity of 50 to 70% of target heart rate. Blood samples collected at rest and after exhaustive exercise before and after 8 weeks, were analyzed for the determination of plasma lipid hydroperoxide (LOOH) level, and activities of glutathione peroxidase (GPx), catalase (CAT) and lactate dehydrogenase (LDH). LOOH level in the training group significantly decreased after the post-training period (p<0.05), but did not alter in the control group (p>0.05). LDH activities significantly increased both control and training groups after the exhaustive exercise (p<0.05). LDH activity was found significantly higher in control group than training group both at rest and after exhaustive exercise (p<0.05). GPx was not significantly altered by training and exhaustive exercise in both groups (p>0.05). In the training group, exhaustive exercise significantly increased CAT level after training period (p<0.05). Consequently, it can be said that endurance training is effective in prevention of lipid peroxidation caused by exhaustive exercise.

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“…Its quantification has been deployed in monitoring the effects of hemodialysis (6) and in the assessment of patients with gout (47) . Acute exercise promotes increases in salivary uric acid levels (19,47) and total antioxidant capacity when compared with baseline (19) . Nevertheless, Youssef et al (61) demonstrated that the total salivary antioxidant capacity of triathletes fell significantly by the end of the season when the values were compared with the beginning of the training period.…”

Section: Non-protein Organic Compoundsmentioning

confidence: 99%

Saliva as a diagnostic fluid in sports medicine: potential and limitations

Nunes¹,

Macedo²

2013

J. Bras. Patol. Med. Lab.

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The use of saliva in the diagnosis of pathologies and/or monitoring of athletes in competitions or trainings is an attractive alternative due to the fact that samples are easily obtained and it is mostly a less invasive method in comparison with venous blood collection. The saliva is a hypotonic fluid in relation to plasma, containing compounds produced in the salivary glands (immunoglobulin A [IgA] and α-amylase) as well as compounds diffused in the plasma (water, electrolytes, proteins, metabolites and hormones). It plays a pivotal role in the protection of oral mucosa against microbes and in food digestion. Its production and composition depend on the sympathetic and parasympathetic nervous system activity, whose antagonistic action may result in different saliva volumes with distinct ionic and protein profiles. The aim of this review was to present a critical analysis of the potential and limitations of saliva as a diagnostic tool in sports medicine. Although there are studies that have deployed it to monitor athletes in training and doping, the standardization of some preanalytical variables are still required, among which the following ones are worth mentioning: the accurate choice of collection system, which allows the easy quantification of volume with adequate sample recovery; well-defined collection schedules in accordance with the circadian variations of the analyte; prevention of sample contamination with blood from oral mucosa lesions. Another key point for its application in sports is the establishment of reference intervals for analytes quantified in the saliva, collected from a population that comprises healthy individual that exercise regularly and systematically, with physical activity progression.

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Effects of Aerobic Exercise on Uric Acid, Total Antioxidant Activity, Oxidative Stress, and Nitric Oxide in Human Saliva

Cited by 53 publications

References 42 publications

Anaerobic exercise affects the saliva antioxidant/oxidant balance in high-performance pentathlon athletes

Anaerobic exercise affects the saliva antioxidant/oxidant balance in high-performance pentathlon athletes

Effects of endurance training on exhaustive exercise-induced oxidative stress markers

Saliva as a diagnostic fluid in sports medicine: potential and limitations

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