Effects of acute exposure to environmentally realistic tebuconazole concentrations on stress responses of kidney and digestive gland of Lymnaea stagnalis

Somuncu, Sezgi; Atmaca, Harika; Ilhan, Suleyman

doi:10.1016/j.etap.2023.104352

Cited by 1 publication

(1 citation statement)

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“…This may be due to the activation of snail metabolism by metaldehyde. TAC represents the combined antioxidant activity of all antioxidants present in biological samples, including both enzymatic and non-enzymatic antioxidants, and the determination of TAC has been widely used as a tool for evaluating the state of redox reactions and the level of total antioxidant capacity in organisms [ 47 ]. Our results found that the treatment increased TAC activity at 24 and 48 h, only female spirochetes decreased after 48 h in the 1/4 LC 50 concentration, and TAC activity was higher at 24 h than at 48 h. This is in line with the findings of Cossi et al [ 48 ] who found that TAC activity in Biomphalaria straminea increases under the influence of organophosphorus insecticides.…”

Section: Discussionmentioning

confidence: 99%

Effect of Metaldehyde on Survival, Enzyme Activities, and Histopathology of the Apple Snail Pomacea canaliculata (Lamarck 1822)

Liu,

Chen,

Zhang

et al. 2024

Biology

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Pomacea canaliculata, as an invasive exotic species in Asia, can adversely affect crop yields, eco-environment, and human health. Application of molluscicides containing metaldehyde is one effective method for controlling P. canaliculata. In order to investigate the effects of metaldehyde on adult snails, we conducted acute toxicological experiments to investigate the changes in enzyme activities and histopathology after 24 h and 48 h of metaldehyde action. The results showed that the median lethal concentrations (LC) of metaldehyde on P. canaliculata were 3.792, 2.195, 1.833, and 1.706 mg/L at exposure times of 24, 48, 72, and 96 h, respectively. Treatment and time significantly affected acetylcholinesterase (AChE), glutathione S-transferase (GST), and total antioxidant capacity (TAC) activity, with sex significantly affecting AChE, GST, and TAC activity and time significantly affecting carboxylesterase (CarE). In addition, the interaction of treatment and time significantly affected the activity of GST, CarE and TAC. In addition, histopathological changes occurred in the digestive glands, gills and gastropods of apple snail exposed to metaldehyde. Histological examination of the digestive glands included atrophy of the digestive cells, widening of the hemolymph gap, and an increase in basophils. In treated snails, the hemolymph gap in the gills was widely dilated, the columnar cells were disorganized or even necrotic, and the columnar muscle cells in the ventral foot were loosely arranged and the muscle fibers reduced. The findings of this study can provide some references for controlling the toxicity mechanism of invasive species.

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Section: Discussionmentioning

confidence: 99%