Effects of Acute and Chronic Heavy Metal (Cu, Cd, and Zn) Exposure on Sea Cucumbers (Apostichopus japonicus)

Li, Li; Tian, Xiangli; Yu, Xiaoyan; Dong, Shuanglin

doi:10.1155/2016/4532697

Cited by 13 publications

(9 citation statements)

References 31 publications

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“…To date, although several studies have reported the distribution of metal elements in sea cucumber Holothuria tubulosa, Australostichopus mollis and Apostichopus japonica (Culha et al, 2016;Li et al, 2016;Slater and Jeffs, 2010;Warnau et al, 2006), there have been few studies concerning heavy metals removal in A. leucoprocta. As an important protein source, it is necessary to assess the heavy metals levels accumulated in A. leucoprocta.…”

Section: Introductionmentioning

confidence: 99%

Distribution and Chemoenzymatic Removal of Heavy Metals in Sea Cucumber Acaudina leucoprocta

Lin

Chen

Jia

et al. 2018

FSTR

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Sea cucumbers are traditional marine food in Asian countries. In this work, the chemical elements accumulated in sea cucumber Acaudina leucoprocta from the East China Sea were measured and analyzed. The contents of Zn, Mn, Cu, As, Pb, Cd and Cr increased with the increase of weight of A. leucoprocta. The levels of Pb and As in all the examined individuals were higher than the maximum residue limits (MRLs) permitted in foodstuffs. The metals were found to be selectively distributed in the body compartments of A. leucoprocta. The highest contents of heavy metals As, Pb were found in intestines and body wall, while the lowest in anus and internal organ. An efficient chemoenzymic method by combining proteolytic enzymatic hydrolysis with citric acid soaking was established to remove the heavy metals in sea cucumber A. leucoprocta. The concentrations of both As and Pb were decreased to below 0.5 mg kg _ 1 in all the samples.

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Section: Introductionmentioning

confidence: 99%

Distribution and Chemoenzymatic Removal of Heavy Metals in Sea Cucumber Acaudina leucoprocta

Lin

Chen

Jia

et al. 2018

FSTR

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“…This may prevent the interaction between Cd 2+ and key enzymes, and luciferase, which is responsible for bioluminescence production, and ultimately decrease the toxicity of Cd towards the bacteria. In addition, based on previous literature, some metals have been proven as a detrimental element for living organisms and the main integral of metabolic enzymes, such as Zn and Cu [ 49 , 50 , 51 ]. These can be toxic to organisms when exceeding threshold levels.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Joint Effect of Acute and Chronic Toxicity for Combined Assessment of Heavy Metals on Photobacterium sp.NAA-MIE

Adnan

Halmi

Gani

et al. 2021

IJERPH

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Predicting the crucial effect of single metal pollutants against the aquatic ecosystem has been highly debatable for decades. However, dealing with complex metal mixtures management in toxicological studies creates a challenge, as heavy metals may evoke greater toxicity on interactions with other constituents rather than individually low acting concentrations. Moreover, the toxicity mechanisms are different between short term and long term exposure of the metal toxicant. In this study, acute and chronic toxicity based on luminescence inhibition assay using newly isolated Photobacterium sp.NAA-MIE as the indicator are presented. Photobacterium sp.NAA-MIE was exposed to the mixture at a predetermined ratio of 1:1. TU (Toxicity Unit) and MTI (Mixture Toxic Index) approach presented the mixture toxicity of Hg2+ + Ag+, Hg2+ + Cu2+, Ag+ + Cu2+, Hg2+ + Ag+ + Cu2+, and Cd2+ + Cu2+ showed antagonistic effect over acute and chronic test. Binary mixture of Cu2+ + Zn2+ was observed to show additive effect at acute test and antagonistic effect at chronic test while mixture of Ni2+ + Zn2+ showing antagonistic effect during acute test and synergistic effect during chronic test. Thus, the strain is suitable and their use as bioassay to predict the risk assessment of heavy metal under acute toxicity without abandoning the advantage of chronic toxicity extrapolation.

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“…: currently set at 0.07 μM for open waters). This has negative repercussions for both marine and terrestrial life 6 – 9 . It is made even more alarming given that copper pollution in the environment has become commonplace 6 – 13 .…”

Section: Introductionmentioning

confidence: 99%

Bioengineering of non-pathogenic Escherichia coli to enrich for accumulation of environmental copper

Gahlot

Taheri

Mahato

et al. 2020

Sci Rep

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Heavy metal sequestration from industrial wastes and agricultural soils is a long-standing challenge. This is more critical for copper since copper pollution is hazardous both for the environment and for human health. In this study, we applied an integrated approach of Darwin’s theory of natural selection with bacterial genetic engineering to generate a biological system with an application for the accumulation of Cu2+ ions. A library of recombinant non-pathogenic Escherichia coli strains was engineered to express seven potential Cu2+ binding peptides encoded by a ‘synthetic degenerate’ DNA motif and fused to Maltose Binding Protein (MBP). Most of these peptide-MBP chimeras conferred tolerance to high concentrations of copper sulphate, and in certain cases in the order of 160-fold higher than the recognised EC50 toxic levels of copper in soils. UV–Vis spectroscopic analysis indicated a molar ratio of peptide-copper complexes, while a combination of bioinformatics-based structure modelling, Cu2+ ion docking, and MD simulations of peptide-MBP chimeras corroborated the extent of Cu2+ binding among the peptides. Further, in silico analysis predicted the peptides possessed binding affinity toward a broad range of divalent metal ions. Thus, we report on an efficient, cost-effective, and environment-friendly prototype biological system that is potentially capable of copper bioaccumulation, and which could easily be adapted for the removal of other hazardous heavy metals or the bio-mining of rare metals.

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Effects of Acute and Chronic Heavy Metal (Cu, Cd, and Zn) Exposure on Sea Cucumbers (Apostichopus japonicus)

Cited by 13 publications

References 31 publications

Distribution and Chemoenzymatic Removal of Heavy Metals in Sea Cucumber <i>Acaudina leucoprocta</i>

Distribution and Chemoenzymatic Removal of Heavy Metals in Sea Cucumber <i>Acaudina leucoprocta</i>

Comparison of Joint Effect of Acute and Chronic Toxicity for Combined Assessment of Heavy Metals on Photobacterium sp.NAA-MIE

Bioengineering of non-pathogenic Escherichia coli to enrich for accumulation of environmental copper

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