Effects of a supplementary diet with specially processed cereals in patients with short bowel syndrome

Pagoldh, Maria; Eriksson, Anders; Heimtun, Erling; Kvifors, Eva; Sternby, Berit; Blomquist, Lars; Lapidus, Annika; Suhr, Ole B.; Lange, Stefan; Karlbom, Urban; Nordström, Daniel; Rettrup, Björn

doi:10.1097/meg.0b013e328303c00a

Cited by 4 publications

(3 citation statements)

References 29 publications

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“…Pagoldh et al ( 87 ) conducted a double-blind trial to investigate the effects of diet supplemented with SPC or with non-processed cereals on health-related quality of life in a heterogeneous group of patients affected by SBS of various aetiologies. Patients differed by short bowel length and intestinal surgical techniques.…”

Section: Antisecretory Factor-inducing Feed In Animal Nutritionmentioning

confidence: 99%

“…Compared with SPC, the non-processed cereals were more effective in reducing daily faecal volume, especially in patients with ulcerative colitis, probably due to the high content of gel-forming dietary fibre that improved fluid absorption. The surgical techniques influenced the clinical effects of the cereal supplementation ( 87 ) . Moreover, the effects of the diet supplementation were more evident in the last part of the trial, probably due to a sensitisation process of the mucosa, which was independent from the type of cereals used in the first part of the trial ( 87 ) .…”

Section: Antisecretory Factor-inducing Feed In Animal Nutritionmentioning

confidence: 99%

“…The surgical techniques influenced the clinical effects of the cereal supplementation ( 87 ) . Moreover, the effects of the diet supplementation were more evident in the last part of the trial, probably due to a sensitisation process of the mucosa, which was independent from the type of cereals used in the first part of the trial ( 87 ) . According to the authors, an interesting approach to SBS would be a diet supplementation targeting increased viscosity of the intestinal content that could prolong the transit time and thus improve the uptake of nutrients ( 85 ) .…”

Section: Antisecretory Factor-inducing Feed In Animal Nutritionmentioning

confidence: 99%

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Antisecretory factor as a potential health-promoting molecule in man and animals

2010

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Antisecretory factor (AF) is a protein secreted in plasma and other tissue fluids in mammals with proven antisecretory and anti-inflammatory activity; its immunohistological distribution suggests a role in the immune system. The expression level and the distribution of AF protein are altered during an immunological response. Exposure to bacterial toxins induces secretion of AF in plasma, probably reflecting a natural defence mechanism to agents causing diarrhoea, thereby contributing to a favourable clinical outcome and disease termination. An increase of AF levels in plasma by dietary means, such as specially processed cereals (SPC), has been demonstrated in human subjects and animals. Administration of SPC to patients affected by inflammatory bowel disease, gastroenteritis and Ménière's disease relieved symptoms and improved quality of life. A recent study showed the positive effect of SPC diet supplementation on prevention of the effects of exposure to low levels of blast overpressure in rats, reducing the extent of intracranial pressure increase and cognitive function impairment. AF-rich egg yolk powder improved health status in children suffering acute and chronic diarrhoea, reducing the frequency and increasing the consistency of stools. This kind of functional food could be used for prophylaxis in populations exposed to a high risk of morbidity and mortality caused by diarrhoea and as a complementary therapy in patients affected by chronic intestinal inflammatory disease to improve well-being. In pig husbandry AF-inducing diets, owing to their antisecretory activity and anti-inflammatory action, are a suitable option as an alternative to antibiotic growth promoters to counteract post-weaning diarrhoea.

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Section: Antisecretory Factor-inducing Feed In Animal Nutritionmentioning

confidence: 99%

Section: Antisecretory Factor-inducing Feed In Animal Nutritionmentioning

confidence: 99%

Section: Antisecretory Factor-inducing Feed In Animal Nutritionmentioning

confidence: 99%

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Antisecretory factor as a potential health-promoting molecule in man and animals

2010

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Enteral approaches in malabsorption

Avitzur

Courtney‐Martin

2016

Best Practice & Research Clinical Gastroenterology

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Short bowel syndrome: searching for the proper diet

Tilg¹

2008

European Journal of Gastroenterology & Hepatology

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Short bowel syndrome occurs subsequent to anatomical and/or functional loss of mainly small bowel. This often-devastating disease leads to weight loss and immune dysfunction. Proper medical management involves adequate substitution and maintenance of fluid, electrolytes, and nutrients. Although several pharmacological therapies such as clonidine, growth hormone, or octreotide have shown promising results in short bowel syndrome, optimal nutritional management is the most important factor in these patients. If enteral nutrition is possible, diet should consist mainly of fat, followed by protein, and less intake of carbohydrates. Supplementary nonprocessed cereals may be beneficial in a certain subgroup of patients. With the recent developments in medical therapy, a balanced diet may allow many patients to become nutritionally autonomous.

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Effects of a supplementary diet with specially processed cereals in patients with short bowel syndrome

Cited by 4 publications

References 29 publications

Antisecretory factor as a potential health-promoting molecule in man and animals

Antisecretory factor as a potential health-promoting molecule in man and animals

Enteral approaches in malabsorption

Short bowel syndrome: searching for the proper diet

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