Effects of a structured counselling-based intervention to improve physical activity behaviour of adolescents and young adult cancer survivors – the randomized phase II Motivate AYA – MAYA trial

Abstract

Objective: To explore whether a structured counselling-based intervention increases vigorous physical activity behaviour of adolescent and young adult cancer survivors. Design: Randomized controlled phase II trial. Setting: University Cancer Center Hamburg, Germany. Subjects: Eighty-nine participants (mean age 24.1 ± 6.3) were randomized to control ( n = 44) or intervention group ( n = 45). Interventions: The intervention group was consulted about physical activity behaviour via interview (week 0), and telephone counselling (weeks 1, 3 and 12). The control group only received general physical activity guidelines for cancer survivors (week 0). Main measures: The primary outcome was the rate of participants with ⩾9 metabolic equivalent (MET)-hours per week of vigorous activity post-intervention, measured with the International Physical Activity Questionnaire. Secondary outcomes included assessing physical activity behaviour (e.g. amount and type of physical activity) and quality of life. Assessments were completed in weeks 0 (baseline), 12 (post-intervention) and 52 (follow-up). Results: Sixty-nine participants completed the post-intervention- and 47 the follow-up-assessment. The rate of participants performing vigorous physical activity increased from baseline to post-intervention for both without differing significantly ( P = 0.541). Both increased their total metabolic equivalent from baseline to post-intervention (intervention group from 55.2 ± 43.7 to 61.7 ± 29.4, control group from 75.3 ± 81.4 to 88.3 ± 80.2). At follow-up the intervention group (73.7 ± 80.2) was more active than baseline when compared to the control group (78.5 ± 50.0). Conclusions: A structured counselling-based physical activity intervention did not significantly impact the level of vigorous physical activity behaviour in adolescent and young adult cancer survivors.

The Effectiveness of Interventions to Reduce Sedentary Time in Different Target Groups and Settings in Germany: Systematic Review, Meta-Analysis and Recommendations on Interventions

“…Ten studies [ 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 ] referred to published protocols [ 79 , 80 , 81 , 82 , 83 , 84 ] or trial registry records (trial IDs reported in Table 1 ) which were consulted in these cases. Nine studies [ 69 , 70 , 73 , 76 , 77 , 78 , 85 , 86 , 87 ] were judged to be of high risk of bias and four studies [ 71 , 72 , 74 , 75 ] to have some concerns. No studies were judged to be of low risk of bias.…”

“…In two instances [ 88 , 89 ], the authors referred to an additional paper containing more detailed information on the respective study [ 90 , 91 ]. Of the 15 included studies, 14 studies [ 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 85 , 87 , 88 , 89 ] were published in peer-reviewed journals, 14 were written in English [ 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 85 , 87 , 88 , 89 ] and one [ 86 ] in German. The country of origin was Germany for 13 studies [ 69 , 70 , 71 , 73 , 74 , 75 , 76 , 77 , 78 , 85 , 86 , 87 , 88 ] and Belgium [ 89 ] and the UK [ 72 ] for one study each.…”

“…One study [ 72 ] did not report the exact number of participants included. One study focused on toddlers [ 89 ], three on preschoolers [ 75 , 88 , 89 ], three on school children [ 78 , 87 , 89 ], one on teenagers [ 76 ], two on adults [ 70 , 72 ], three on older adults [ 69 , 71 , 77 ], one on office workers [ 85 ] and three on people with chronic diseases [ 73 , 74 , 86 ].…”

“…The intervention duration was less than six months in nine studies [ 69 , 70 , 71 , 73 , 74 , 76 , 85 , 86 , 87 ], at least six months but less than twelve months in three cases [ 72 , 75 , 77 ] and it lasted twelve months or longer in three studies [ 78 , 88 , 89 ]. Five studies encompassed follow-up after the outcome assessment at the end of the intervention to assess long-term effects [ 70 , 73 , 74 , 75 , 86 ].…”

“…The intervention duration was less than six months in nine studies [ 69 , 70 , 71 , 73 , 74 , 76 , 85 , 86 , 87 ], at least six months but less than twelve months in three cases [ 72 , 75 , 77 ] and it lasted twelve months or longer in three studies [ 78 , 88 , 89 ]. Five studies encompassed follow-up after the outcome assessment at the end of the intervention to assess long-term effects [ 70 , 73 , 74 , 75 , 86 ]. Six studies examined multicomponent interventions [ 75 , 76 , 78 , 85 , 88 , 89 ], eight studies focused on personal behavior interventions [ 69 , 70 , 71 , 72 , 73 , 74 , 77 , 86 ] and one targeted the physical environment [ 87 ].…”