Effects of a solid formulation containing lectin-rich fraction of Moringa oleifera seeds on egg hatching and development of Aedes aegypti larvae

Silva, Livia Lais de Santana; Silva, Stella Cristina Cabral; Oliveira, Ana Patrícia Silva de; Nascimento, Jéssica da Silva; Silva, Emerson de Oliveira; Coelho, Luana Cassandra Breitenbach Barroso; Neto, Pedró José Rolim; Navarro, Daniela Maria do Amaral Ferraz; Napoleão, Thiago Henrique

doi:10.1016/j.actatropica.2020.105789

Cited by 8 publications

(3 citation statements)

References 32 publications

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“…[4] Lectins are proteins widely distributed in nature, which found in animals, plants, bacteria and viruses, have selective binding sites to carbohydrates or glycan portions from glycoconjugates. [5,6] Lectin-carbohydrate interactions become a viable tool for the analysis of biological phenomena [7] seeking to observe physiological responses to these systems, such as mitogenic doi.org/10.1002/cbdv.202200515 activity and cell-cell interaction. [8,9] These interactions occur due to the existence of different intermolecular forces, including hydrogen bonds, Van der Walls and hydrophobic interactions.…”

Section: Introductionmentioning

confidence: 99%

Biosensor Characterization from Cratylia mollis Seed Lectin (Cramoll)‐MOF and Specific Carbohydrate Interactions in an Electrochemical Model

Carvalho

Araújo

Silva

et al. 2022

Chemistry & Biodiversity

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Biosensors are small devices known for their selectivity, high specificity and sensitivity to the respective analyte, at low concentrations. We developed an electrochemical biosensor using the crystalline polymer MOF-[Cu 3 (BTC) 2 (H 2 O) 2 ] n to characterize Cratylia mollis seed lectin (Cramoll) and its interaction with free carbohydrate (glucose) and carbohydrates on the surface of rabbit erythrocytes. The electrochemical potentials presented by the exponential curves that vary from 96 to 142 mV in relation to concentrations of 10 to 20 mM of glucose are decisive for the use of the system containing gold electrode/MOF/Cramoll for the characterization of biological models due to its high sensitivity. As well as the kinetic behavior presented in the cyclic voltammograms, with a cathodic current response of 0.000 3 A for a glucose concentration of 15 mM. These results were due to the high specificity of Cramoll under these conditions, promoting stability of surface charges at the Cramoll/electrode interface. This phenomenon facilitates the monitoring of the interaction with free glucose present in the electrolyte medium by potentiometric and amperometric methods and with carbohydrates present on the surface of rabbit erythrocytes through the potentiometric method. Through scanning electron microscopy (SEM) it was possible to observe Cramoll immobilized on the MOF surface, proving the specificity of the ligand (glucose-lectin) through the morphological lectin changes in this process. This electrochemical model, Cramoll/ MOF biosensor, is effective for evaluating free lectin/carbohydrate or in the erythrocyte membrane.

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Section: Introductionmentioning

confidence: 99%

Biosensor Characterization from Cratylia mollis Seed Lectin (Cramoll)‐MOF and Specific Carbohydrate Interactions in an Electrochemical Model

Carvalho

Araújo

Silva

et al. 2022

Chemistry & Biodiversity

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“…aegypti mosquitoes, and this formulation method is proposed as a new control strategy for Ae. aegypti populations [214]. Phytochemicals break down rapidly and this causes a need for continuous and more frequent applications in the field for a satisfactory impact on mosquito control.…”

Section: How To Improve Plant-based Bioinsecticide Efficacy In Mosqui...mentioning

confidence: 99%

Plant-Based Bioinsecticides for Mosquito Control: Impact on Insecticide Resistance and Disease Transmission

Demirak

Canpolat

2022

Insects

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The use of synthetic insecticides has been a solution to reduce mosquito-borne disease transmission for decades. Currently, no single intervention is sufficient to reduce the global disease burden caused by mosquitoes. Problems associated with extensive usage of synthetic compounds have increased substantially which makes mosquito-borne disease elimination and prevention more difficult over the years. Thus, it is crucial that much safer and effective mosquito control strategies are developed. Natural compounds from plants have been efficiently used to fight insect pests for a long time. Plant-based bioinsecticides are now considered a much safer and less toxic alternative to synthetic compounds. Here, we discuss candidate plant-based compounds that show larvicidal, adulticidal, and repellent properties. Our discussion also includes their mode of action and potential impact in mosquito disease transmission and circumvention of resistance. This review improves our knowledge on plant-based bioinsecticides and the potential for the development of state-of-the-art mosquito control strategies.

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“…and their major constituents (geranial and d-limonene) exhibited strong ovicidal activity against many mosquitoes species like Anopheles indica 7 , Ae. aegypti [20][21][22] , and Culex quinquefasciatus 23 . Furthermore, combined formulations of EOs and EO constituents showed even higher e cacy than their individual EOs [24][25] .…”

Section: Introductionmentioning

confidence: 99%

Ovicidal toxicity of plant essential oils and their major constituents against two mosquito vectors and their non-target aquatic predators

Moungthipmalai

Puwanard

Aungtikun

et al. 2022

Preprint

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Plant essential oil (EO) is a natural alternative to synthetic chemical insecticides for mosquito control. EOs from Citrus aurantium L., Cymbopogon citratus (Stapf.), and Cinnamomum verum (J. Presl.) were selected for topical assay of their ovicidal activity against Aedes aegypti L. and Aedes albopictus (Skuse). Their efficacy was compared to that of 1% (w/w) temephos. In addition, their non-toxicity against aquatic mosquito predators, Poecilia latipinna and Poecilia reticulate, was tested. Found by GC-MS analysis, the major constituent of C. verum EO was trans- cinnamaldehyde, of C. aurantium EO was d-limonene, and of C. citratus EO was geranial. Both C. verum EO and trans-cinnamaldehyde at a high concentration (30,000 ppm) exhibited high ovicidal activity against Ae. aegypti and Ae. albopictus eggs after 48 h of incubation with an inhibition rate of 91.0–93.0% for C. verum EO and 96.7–95.2% for trans-cinnamaldehyde. The combination of C. verum EO + geranial exhibited the strongest synergistic inhibition activity (100%) against the two mosquito vectors and was five times more effective than temephos. Moreover, they were not toxic to the non-target fishes. As a safe ovicidal agent for mosquito egg control, the combination of C. verum EO + geranial has excellent potential.

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Effects of a solid formulation containing lectin-rich fraction of Moringa oleifera seeds on egg hatching and development of Aedes aegypti larvae

Cited by 8 publications

References 32 publications

Biosensor Characterization from Cratylia mollis Seed Lectin (Cramoll)‐MOF and Specific Carbohydrate Interactions in an Electrochemical Model

Biosensor Characterization from Cratylia mollis Seed Lectin (Cramoll)‐MOF and Specific Carbohydrate Interactions in an Electrochemical Model

Plant-Based Bioinsecticides for Mosquito Control: Impact on Insecticide Resistance and Disease Transmission

Ovicidal toxicity of plant essential oils and their major constituents against two mosquito vectors and their non-target aquatic predators

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