Effects of a Skin Barrier Cream on Management of Incontinence-Associated Dermatitis in Older Women

Kon, Yuka; Ichikawa-Shigeta, Yoshie; Iuchi, Terumi; Nakajima, Yukari; Nakagami, Gojiro; Tabata, Keiko; Sanada, Hiromi; Sugama, Junko

doi:10.1097/won.0000000000000353

Cited by 26 publications

(44 citation statements)

References 28 publications

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“…On univariate analysis, Barthel Index, Braden Scale Score, NRS2002 scale score, serum albumin level, presence of infection, faecal incontinence, frequency of faecal incontinence, stool property, double incontinence and PAT scores of patients with and without IAD showed significant differences ( p < 0.05). Some of these research results are similar to those of other studies (Campbell et al., ; Chianca et al., ; Kon et al., ). However, the relationship of infection with IAD needs to be confirmed by further investigations.…”

Section: Discussionsupporting

confidence: 91%

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Incidence and risk factors of incontinence‐associated dermatitis among patients in the intensive care unit

Wang

Zhang

et al. 2018

Journal of Clinical Nursing

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Section: Discussionsupporting

confidence: 91%

“…Therefore, such skin is less capable to defend against external irritants and is susceptible to damage caused by incontinence, thereby leading to IAD. (Campbell et al, 2016;Chianca et al, 2017;Kon et al, 2017). However, the relationship of infection with IAD needs to be confirmed by further investigations.…”

Section: Discussionmentioning

confidence: 98%

Incidence and risk factors of incontinence‐associated dermatitis among patients in the intensive care unit

Wang

Zhang

et al. 2018

Journal of Clinical Nursing

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“…Traditionally, MASD/IAD is treated with the application of zinc oxide ointment or cream [4,5]. However, this requires the use of gloves and multiple zinc oxide applications to ensure adequate coverage, increasing nursing time per patient and the use of consumables.…”

Section: Discussionmentioning

confidence: 99%

“…Incontinence-associated dermatitis (IAD), the most common form of moisture-associated skin damage (MASD), is a major concern with hospitalized patients and puts them at higher risk for skin breakdown and ulceration [1-3]. Zinc oxide has traditionally been utilized to prevent and treat MASD/IAD [4,5]. Zinc oxide ointments have been applied with gloved hands directly to the area of concern, often the perianal and perineal area of patients.…”

Section: Introductionmentioning

confidence: 99%

Economic Model for Cost Containment: Evaluating the Utilization of a Touch-free Zinc Oxide in an Acute Care Hospital

Tolentino

Dick

2019

Cureus

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Introduction Incontinence-associated dermatitis (IAD), the most common form of moisture-associated skin damage (MASD), puts patients at higher risk for ulceration. Treatment of MASD/IAD includes application of zinc oxide, typically applied using gloved hands directly to the area of concern. A computational model was utilized to examine a cost comparison of a touch-free zinc oxide treatment versus traditional zinc oxide for MASD/IAD. Methods A literature search was performed using PubMed, a nursing journal database (CINAHL), and MEDLINE for publications from January 1, 2010 through November 30, 2017. Data on prevalence of MASD/IAD, average length of stay, and time to heal were extracted and utilized in the computational model. Cost per patient stay and annual total hospital costs were calculated for three and four applications of zinc oxide per patient with an averaged prevalence rate of 25% for a hypothetical hospital. Results The computational model estimated a range of cost savings between $181.88 to $2,000.63 per patient stay, and $4,728.88 to $52,016.25 over a 12-month period compared to traditional zinc oxide application. Conclusions The computational model estimated a cost savings of up to $52,016.25 per year in a hypothetical 250-bed acute care hospital compared to traditional zinc oxide application. Future prospective studies examining clinical effectiveness and health economics of touch-free zinc oxide are necessary.

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“…IAD is defined as inflammation characterised by redness, with or without blistering, and erosion that occurs with chronic or repetitive exposure to urine or faeces. 4 Despite the implementation of preventative strategies, [5][6][7] high IAD prevalence and incidence rates (ranging from 5.2% to 27%) have been reported worldwide, with cumulative incidence rates ranging from 3.4% to 50%. 8 IAD negatively affects patients by causing discomfort such as itching or pain, 8 which impacts quality of life.…”

Section: Introductionmentioning

confidence: 99%

Combination of urease inhibitor and antiseptic inhibits urea decomposition‐induced ammonia production by Proteus mirabilis

Mugita

Nakagami

Minematsu

et al. 2020

International Wound Journal

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The decomposition of urea into ammonia by urease‐producing bacterium shows an elevation in the pH level, which can lead to incontinence‐associated dermatitis (IAD). This study aimed to examine the efficacy of a combination of antiseptic and urease inhibitor in inhibiting the decomposition of urea by the urease‐producing bacterium Proteus mirabilis. We performed in vitro assays to compare the effects of a combination of antiseptic and urease inhibitor, antiseptic only, urease inhibitor only, and an untreated control with the effects of a urea‐containing solution. Cultured P. mirabilis was mixed with urea‐containing solution, followed by the addition of antiseptic and/or urease inhibitor. The main outcome used to assess the efficacy of the different treatments was ammonia concentration at 4‐hours post‐treatment initiation, and multiple comparison analysis was performed using Dunnett's test to compare the results between groups. Ammonia concentrations in samples treated with either antiseptic or urease inhibitor were lower than those in the untreated control, while the combination of antiseptic and urease inhibitor resulted in decreased ammonia concentrations compared with either treatment alone. Therefore, the application of both urease inhibitor and antiseptic is more effective for the inhibition of urea decomposition by urease‐producing bacteria. Novel preventive strategies using these reagents may be effective for preventing IAD.

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Effects of a Skin Barrier Cream on Management of Incontinence-Associated Dermatitis in Older Women

Abstract: Study findings suggest that a barrier cream designed to enhance the skin's moisture barrier and act as a skin protectant increased stratum corneum hydration, reduced cutaneous pH, and reduced erythema.

Cited by 26 publications

References 28 publications

Incidence and risk factors of incontinence‐associated dermatitis among patients in the intensive care unit

Incidence and risk factors of incontinence‐associated dermatitis among patients in the intensive care unit

Economic Model for Cost Containment: Evaluating the Utilization of a Touch-free Zinc Oxide in an Acute Care Hospital

Combination of urease inhibitor and antiseptic inhibits urea decomposition‐induced ammonia production by Proteus mirabilis

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