Effects of a single high dose of Chlorpyrifos in long-term feeding, ethanol consumption and ethanol preference in male Wistar rats with a previous history of continued ethanol drinking

Chronic exposure to chlorpyrifos triggered body weight increase and memory impairment depending on human apoE polymorphisms in a targeted replacement mouse model

“…To date numerous studies have endorsed the neurotoxic and behavioral effects of CPF in both human [6,20,21,55,62] and animal models [10,37,40,63,67]. CPF exerts its insecticidal activity by irreversibly inhibiting cholinesterases (ChE) and disrupting cholinergic function in the nervous system.…”