Effects of a rumen protected B vitamin blend  substituted for biotin upon milk production and  component yield in lactating dairy cows

Evans, E.; Mair, D.T.

doi:10.4236/ojas.2013.32014

Cited by 5 publications

(4 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is noteworthy that our findings align with previous research [ 39 , 40 , 41 ], because the essential role of B vitamins in critical metabolic processes such as gluconeogenesis, fatty acid synthesis, and protein synthesis in dairy cows is well-established. Furthermore, the components of INC, specifically active dry yeast and Selenomethionine, may have played pivotal roles in the observed improvements in milk production performance [ 42 , 43 ].…”

Section: Discussionsupporting

confidence: 92%

Supplementation with Combined Additive Improved the Production of Dairy Cows and Their Offspring with Maintenance of Antioxidative Stability

Zhang,

Nuermaimaiti,

Hao

et al. 2024

Antioxidants

View full text Add to dashboard Cite

Oxidative stress damage in periparturient cows decreases both production and their health; supplementation with complex additives during the periparturient period has been used as an important strategy to enhance the antioxidant status and production of dairy cows. The periparturient cows not only risk a negative energy balance due to reduced dry matter intake but also represent a sensitive period for oxidative stress. Therefore, we have developed an immunomodulatory and nutritional regulation combined additive (INC) that hopefully can improve the immune status and production of cows during the periparturient period and their offspring health and growth by improving their antioxidant stress status. The INC comprised a diverse array of additives, including water-soluble and fat-soluble vitamins, Selenomethionine, and active dry Saccharomyces cerevisiae. Forty-five multiparous Holstein cows were randomly assigned to three treatments: CON (no INC supplementation, n = 15), INC30 (30 g/d INC supplementation, n = 15), and INC60 (60 g/d INC supplementation, n = 15) based on last lactation milk yield, body condition score, and parity. Newborn calves were administered 4 L of maternal colostrum originating from the corresponding treatment and categorized based on the treatment received by their respective dams. The INC not only served to maintain the antioxidative stress system of dairy cows during the periparturient period but also showed a tendency to improve the immune response (lower tumor necrosis factor and interleukin-6) during the perinatal period. A linear decrease in concentrations of alkaline phosphatase postpartum and β-hydroxybutyrate was observed with INC supplementation. Milk fat yield, milk protein yield, and energy-corrected milk yield were also increased linearly with increasing additive supplementation. Calves in the INC30 group exhibited greater wither height and chest girth but no significant effect on average daily gain or body weight. The diarrhea frequency was linearly decreased with the incremental level of INC. Results indicate that supplementation with INC in peripartum dairy cows could be a major strategy to improve immune response, decrease inflammation, maintain antioxidant stress status in transition dairy cows, and have merit in their calves. In conclusion, this study underlines the benefits of INC supplementation during the transition period, as it improved anti-inflammatory capacity, could positively impact antioxidative stress capacity, and eventually enhanced the production performance of dairy cows and the health and growth of calves.

show abstract

Section: Discussionsupporting

confidence: 92%

Supplementation with Combined Additive Improved the Production of Dairy Cows and Their Offspring with Maintenance of Antioxidative Stability

Zhang,

Nuermaimaiti,

Hao

et al. 2024

Antioxidants

View full text Add to dashboard Cite

show abstract

“…Because of the novelty of the RPFA evaluated and in the absence of other corroborating information making definitive conclusions regarding the potential efficacy of providing a rumen-protected source of FA or other B vitamins is not currently feasible. Other studies where a rumen-protected source of FA ( Li et al, 2016 ; Wang et al, 2016 ) or a rumen-protected blend of B vitamins have been fed ( Evans and Mair, 2013 ; Kaur et al, 2018 ) have reported positive responses. Previous research as well as the more recent information provided by Deters et al (2021) in addition to the present research would indicate blood levels of both FA and vitamin B 12 may be inadequate at critical times to meet demands for reproduction, lactation, growth, or health in dairy and beef cattle.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of feeding ruminal-protected folate and cobalt pectinate on growth performance, carcass characteristics and plasma vitamin B12 and folate status in finishing beef steers

Word¹,

Holland²,

Karr³

et al. 2022

Translational Animal Science

View full text Add to dashboard Cite

A large pen feedlot study was conducted to evaluate response of yearling steers fed novel sources of rumen-protected folate (RPFA) and cobalt (cobalt pectinate; Co-PECT) on plasma levels of vitamin B12 and folate, growth performance and carcass characteristics. A total of 2,100 steers (initial BW = 381 ± 45.2 kg.) were enrolled in the study at the time of randomization with 2,091 steers started on treatment diets following transition to the finishing diet. A generalized randomized block design with sampling error (GRBD) with two treatments and 15 pen replications per treatment (5 blocks x 6 pens/block; 30 pens total with 70 steers/pen) were evaluated with pen serving as the experimental unit. A control (CON) treatment consisted of the standard finishing diet while the test diet consisted of the standard finishing diet providing 3.0 mg∙kg -1 DM of RPFA and 1.0 mg∙kg -1 DM total supplemental cobalt with approximately half coming from Co-PECT (TEST). Blood samples were collected from 60 randomly selected steers at study initiation and prior to shipping for plasma B12 and folate measurement. Data were analyzed with the model including fixed effects of treatment, block, and treatment within block interaction. Live growth performance was not affected by treatment; however, carcass-adjusted performance and hot carcass weight were numerically improved by TEST in 3 of the 5 blocks (treatment x within block interaction, P ≤ 0.03) of cattle. Plasma levels for both folic acid and vitamin B12 were extremely low at study initiation and increased over the course of the feeding period. Feeding TEST increased (P < 0.01) plasma B12 levels compared to CON by the completion of the trial; however, mean levels would still be considered marginal. Plasma folate was lower (P < 0.05) in TEST steers at the beginning of the study, with no difference between treatments by the time cattle were shipped. Results suggested that cattle coming into the feedlot may be of low or marginal status in both plasma folate and vitamin B12. While status of folate and B12 improved in both CON and TEST with days on feed, providing RPFA and Co-PECT further helped improve vitamin B12 status; although, overall levels remained low, which may have affected the overall response to RPFA. Additional research is required to better understand the role of B vitamin supplementation for growing-finishing feedlot and develop methods for assessing status and improving potential responses.

show abstract

“…The NRC (2001) calculated an estimate and reported only folic acid and pantothenic acid to be the limiting B vitamins. However, in the recent past, numerous studies have shown an increase in milk production or component yield (or both) when cows are supplemented with vitamin B compounds (Sacadura et al, 2008;Chen et al, 2011;Evans and Mair, 2013). Similarly, a positive effect of supplementation on health has also been reported, especially in early lactation dairy cows (Graulet et al, 2007;Duplessis et al, 2014;Li et al, 2016), which is achieved via improvement in metabolic efficacy.…”

Section: Introductionmentioning

confidence: 99%

Rumen-protected B vitamin complex supplementation during the transition period and early lactation alters endometrium mRNA expression on day 14 of gestation in lactating dairy cows

Kaur

Hartling

Burnett

et al. 2019

Journal of Dairy Science

View full text Add to dashboard Cite

Greater metabolic demands in high-producing dairy cows are believed to be a cause of sub-fertility in these animals. Previously, supplementation with vitamin B complex molecules has shown benefits in improving milk production, health, and reproductive efficiency of dairy cows. The primary aim of this project was to determine the effects of rumen-protected vitamin B complex supplementation of 100 g of Transition VB (Jefo, St. Hyacinthe, QC, Canada) and 4 g of Lactation VB (VB; Jefo), during the transition and early lactation periods, respectively, compared with a control diet containing no supplementation on d 14 endometrial outcomes of pregnancy. In the vitamin B supplemented cows, we expect to see a change in the mark-up of endometrial genes important for embryo survival before implantation. Multiparous Holstein cows were enrolled into the study 3 wk before parturition and were randomly assigned to either the VB or control treatment. Twice-a-week blood samples, weekly milk samples, and daily feed intake were collected. Cows were enrolled onto a double-ovsynch protocol at 33 ± 3 d postpartum and inseminated by timed artificial insemination. Milk production and components, concentrations of BHB, haptoglobin, and progesterone in serum, and ovarian dynamics were also measured, but no treatment effect was observed. The uterus was flushed on d 14 after artificial insemination (around 72 DIM) for conceptus collection, and endometrial samples were collected at the same time. Overall, 42 cows were flushed and 13 embryos were collected. Analysis of mRNA expression of genes related to embryo development, immune system, adhesion, and regulation of vitamin B molecules showed that OXTR, MUC5B, MUC1, IL1B, SPP, TRD, FZD8, and FOLR1 genes were significantly upregulated in the VB group. Vitamin B supplementation had no effect on the size of the embryo and ovulatory follicle or corpus luteum diameter at embryo collection. In conclusion, the benefits of strategic dietary VB supplementation during the transition and early lactation might be directly linked to endometrial functions required for embryo survival during the peri-implantation period.

show abstract

Effects of a rumen protected B vitamin blend substituted for biotin upon milk production and component yield in lactating dairy cows

Cited by 5 publications

References 11 publications

Supplementation with Combined Additive Improved the Production of Dairy Cows and Their Offspring with Maintenance of Antioxidative Stability

Supplementation with Combined Additive Improved the Production of Dairy Cows and Their Offspring with Maintenance of Antioxidative Stability

Evaluation of feeding ruminal-protected folate and cobalt pectinate on growth performance, carcass characteristics and plasma vitamin B12 and folate status in finishing beef steers

Rumen-protected B vitamin complex supplementation during the transition period and early lactation alters endometrium mRNA expression on day 14 of gestation in lactating dairy cows

Contact Info

Product

Resources

About