Effects of a novel probiotic, <i>Bifidobacterium longum bv. infantis</i> CCUG 52486 with prebiotic on the B-cell response to influenza vaccination

Enani, Sumia; Childs, Caroline E.; Przemska, A.; Maidens, Catherine; Dong, Honglin; Rowland, Ian; Tuohy, Kieran; Todd, Susan; Gosney, Margot; Yaqoob, Parveen

doi:10.1017/s0029665114000238

Cited by 3 publications

(1 citation statement)

References 1 publication

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“…Bifidobacterium longum bv infantis CCUG 52486 kökeninin grip aşısı vd. aşılara yanıt olarak IgG üreten bellek B hücrelerinin sayısını artırması buna en güzel örnektir (36).…”

Section: B2 Probiyotikler Ve B Lenfositleriunclassified

Gıda Kaynaklı İmmünomodülatörler

Özbalak¹

2020

Experimed

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Let food be thy medicine and let medicine be thy food." This aphorism refers to the pivotal role played by nutrition in medicine. The door of a "nutrition renaissance" has been opened with the striking disclosure of the relationship between nutrition and microbiota in the pathogenesis of many diseases, which has been better understood in the recent years. A person, once again, is "what he/ she eats. " Foods become "functional" after their integration into the unique features of the intestinal immune system, such as oral tolerance, secretory Immunoglobulin A, local lymphoid foci, regulator cellular immunity, and diversity of commensal microbiome. It is possible to achieve strong immunomodulatory effects through an appropriate selection of probiotics, prebiotics, and synbiotics. Animal proteins and plant-derived peptides also exert immunomodulatory effects. It has been reported that the use of glutamine supplements from wheat protein (gluten) in patients helps in lowering the nosocomial infection rate and the duration of mechanical ventilation. Vitamin A contributes immensely in maintaining the mucosal epithelial integrity and aids in strengthening the neutrophil response to infectious agents. Vitamin B12 has a strong immunomodulatory effect and facilitates the increase in CD8 + T lymphocyte count and natural killer cell activity. Vitamin C has well-defined antioxidant efficacy. Vitamin D strengthens the innate immune response by stimulating cell proliferation and differentiation. The regulatory effects of many foods and food ingredients such as turmeric, garlic, carrot, eggplant, kiwi, and honey in our kitchen on both innate and adaptive immunity serve as the foundation for anticancer, anti-inflammatory, and antioxidant nutrition therapies. Thus, our food continues to be our medicine.

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“…Bifidobacterium longum bv infantis CCUG 52486 kökeninin grip aşısı vd. aşılara yanıt olarak IgG üreten bellek B hücrelerinin sayısını artırması buna en güzel örnektir (36).…”

Section: B2 Probiyotikler Ve B Lenfositleriunclassified

Gıda Kaynaklı İmmünomodülatörler

Özbalak¹

2020

Experimed

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Role of probiotics and prebiotics in immunomodulation

Yahfoufi

Mallet

Graham

et al. 2018

Current Opinion in Food Science

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Gut Dysbiosis and Diabetic Foot Ulcer: Role of Probiotics

et al. 2022

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Diabetic foot ulcer (DFU) is a multifactorial disease and one of the complications of diabetes. The global burden of DFU in the health sector is increasing at a tremendous rate due to its cost management related to hospitalization, medical costs and foot amputation. Hence, to manage DFU/DWs, various attempts have been made, including treating wounds systematically/topically using synthetic drugs, herbal drugs, or tissue engineering based surgical dressings. However, less attention has been paid to the intrinsic factors that are also the leading cause of diabetes mellitus (DM) and its complications. One such factor is gut dysbiosis, which is one of the major causes of enhancing the counts of Gram-negative bacteria. These bacteria produce lipopolysaccharides, which are a major contributing factor toward insulin resistance and inflammation due to the generation of oxidative stress and immunopathy. These all lead to DM and DFU. Probiotics are the commercial form of beneficial gut microbes that are taken as nutraceuticals by people of all ages to improve gut immunity and prevent gut dysbiosis. However, the role of probiotics has been less explored in the management of DFU. Hence, the therapeutic potential of probiotics in managing DFU is fully described in the current review. This report covers the linkage between gut dysbiosis and DFU, sources of probiotics, the mechanisms of probiotics in DW healing, and the impact of probiotic supplementation in treating DFU. In addition, techniques for the stabilization of probiotics, market status, and patents related to probiotics have been also covered. The relevant data were gathered from PubMed, Scopus, Taylor and Francis, Science Direct, and Google Scholar. Our systematic review discusses the utilization of probiotic supplementation as a nutraceutical for the management of DFU.

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Effects of a novel probiotic, Bifidobacterium longum bv. infantis CCUG 52486 with prebiotic on the B-cell response to influenza vaccination

Cited by 3 publications

References 1 publication

Gıda Kaynaklı İmmünomodülatörler

Gıda Kaynaklı İmmünomodülatörler

Role of probiotics and prebiotics in immunomodulation

Gut Dysbiosis and Diabetic Foot Ulcer: Role of Probiotics

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