Effects of a Chayotte (Sechium edule) Extract (Macerated) on the Biochemistry of Blood of Wistar Rats and on the Action Against the Stannous Chloride Effect

Abstract

The use of natural products as medicines has been growing in the entire world. There are concerns that these products may contain potentially toxic ingredients and contaminants such as heavy metals. The labeling of blood constituents with technetium-99m has been influenced by the presence of natural extracts. We evaluated the influence of a chayotte (Sechium edule) extract (100% v/v macerated) on the labeling of blood elements with 99mTc. The animals were treated with the extract during 15 days. Samples of blood were carried out with specific blood biochemistry kits. The present study analyzed the influence ofchayotte in the survival of the strain of Escherichia coli AB1157 submitted to reactive oxygen species induced by stannous chloride. There was a reduction of the lethal effect induced by stannous chloride on the survival of the E. coli culture in the presence of chayotte. The results indicated a decrease in the level of glucose and globulin The effect of the extract could be explained by its metabolic transformation inducing the generation of oxidant metabolites. The culture of bacteria when was treated with stannous chloride and chayotte simultaneously, the extract could be reacting with stannous chloride ions, protecting them against the oxidation avoiding the generation of reactive oxygen species.

Partial characterization of novel inulin‐like prebiotic fructooligosaccharides of Sechium edule (Jacq.) Sw. (Cucurbitaceae) tuberous roots

“…Dire et al. (2007) reported that the fruit extract could reduce the plasma glucose and globulin level.…”

“…The tuberous roots polysaccharides have quality starch and fiber stability under normal cooking conditions (Shiga et al., 2015); the hydroalcoholic acetone fraction has the most vasorelaxant effect (Lombardo‐Earl et al, 2014). Moreover, this plant's different extracts also have antibacterial properties (Dire et al., 2007; Ordoñez et al., 2006; Yang et al., 2015). The above earlier studies have proven that the plant is a repository of many versatile nutritional and functional ingredients to contribute to better health.…”

Antioxidant activity, total phenolic content, and nutrient composition of Chayote shoot (Sechium edule, Jacq. Swartz) from Kundasang, Sabah

“…Researchers report that pharmacological studies confirm that leaves, fruits, and chayote seeds exhibit diuretic, antihypertensive, cardiovascular, and anti-inflammatory properties [6]. This plant is also reported to contain antibacterial [6][7][8][9][10] and antiepileptic activity [11]. Referring to the anti-cardiovascular properties of chayote, previous studies have found that flavonoids in shoots reduce serum lipid and cholesterol content and prevent atherosclerosis [9].…”