Effects of a 50 Hz electric field on plasma lipid peroxide level and antioxidant activity in rats

Harakawa, Shinji; Inoue, Noboru; Hori, Takamitsu; Tochio, Koji; Kariya, Takehiko; Takahashi, Kimiko; Doge, Fuyuki; Suzuki, Hiroshi; Nagasawa, Hideyuki

doi:10.1002/bem.20137

Cited by 55 publications

(39 citation statements)

References 24 publications

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“…Under our experimental conditions it was also possible to note a significant increase of ROS production in two tested cell lines even with a different qualitative and quantitative timecourse. It should be mentioned that "in vivo" experiments in literature also seem to confirm that chronic exposure to ELF-EMF is able to generate a stress oxidative status [32][33][34]. The "in vitro" experiments reported here, as well as the results derived from "in vivo" techniques [13,22,24,25,28,35,36] in mice, show that the presence of ELF-EMF can induce a variable and specie-specific alteration of the stress oxidative pathway.…”

Section: Discussionsupporting

confidence: 79%

ELF-EMFs INDUCED EFFECTS ON CELL LINES: CONTROLLING ELF GENERATION IN LABORATORY

Farina

Mariggiò³

et al. 2010

PIER B

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Abstract-The aim of this paper is to discuss the effects of the exposure to Extremely Low Frequency ElectroMagnetic Fields (ELFEMFs) on non-and excitable cells using in vitro cell models, namely neuron-like cell line (PC12), glioblastoma-derived GL15 cells as glial model and C2C12 myocytes as muscle model, focusing our attention on standardized protocols for ELF-EMFs generation and exposure. A major issue in laboratory -and likely in nature -studies about possible biological effects of ELF waves is the difficulty in providing standard, reproducible environmental conditions. Hence, as part of the work we have developed an exposure system including a probing scanner, able to sample a given volume and to measure the timevarying magnetic field vector. The system allows detection, monitoring and removal of electromagnetic noise sources, as well as means to assess field homogeneity in terms of intensity and polarization.

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Section: Discussionsupporting

confidence: 79%

ELF-EMFs INDUCED EFFECTS ON CELL LINES: CONTROLLING ELF GENERATION IN LABORATORY

Farina

Mariggiò³

et al. 2010

PIER B

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“…This may be due to interaction with moving charges and enzymes activities rates in cell-free systems increasing transcript levels for specific genes, or interacts directly with electrons in DNA to affect protein biosynthesis [5,49]. Exposure to a low magnetic field decreased plasma peroxide level in stressed rats [56]. It is possible that EMF can ameliorate the deleterious effects of Free radicals by decreasing the chemical reactions that caused damage to DNA, proteins and lipids [2].…”

Section: Effect Of Magnetic Water On Biochemical Parametersmentioning

confidence: 99%

Biological Effects of Magnetic Water on Human and Animals

Ebrahim¹

2017

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Abstract:The aim of the present study was to investigate the beneficial effects of magnetized water for human and animals. There was an improvement in water quality when exposed to the magnetic field with considerable change in the pH, total dissolved solids, total hardness, conductivity, salinity, dissolved oxygen, evaporating temperature, minerals, organic matter and total count of bacteria. Therefore it's penetration into cell wall would be facilitated which can accelerate ordinary diffusion of water that is vital for growth of different organs. Patients uses magnetic water for digestive, urinary and nervous problems, ailments like mastitis, pains and swellings, painful urination and many other disorders. Magnetized water has been found effective in alleviating colds, coughs, bronchitis, all types of fever and more, arthritis pain, reducing blood pressure, recovering quickly from a stroke, and it helpful in the regularization of women's menses. Also, treatment with magnetic water was very effective in breaking up kidney and gall bladder stones into small particles. The water also prevented further formation of stones in the kidneys and gallbladder. Magnetic water may prevent aging and fatigue by increasing the cell membrane permeability. Effectiveness of magnetized water in the prevention and treatment of atherosclerosis has been shown in some animal and human studies. It has been reported that magnetic water help unclog the arteries and veins of deposits of cholesterol and salts and normalize the circulatory system. Also, magnetized water can be helpful in weight control, as an adjutant to a correct diet because this water improves metabolic activity, it may be helpful in burning up excessive fatty tissue. Magnetized drinking water improves nutrient digestibility, saves water consumption, optimizing rumen fermentation parameters, and it could an effective way to reduce methane production and contributing to mitigate environmental impact in livestock, positive animal health, which is reflected in the increase in milk yield and its component and improves blood picture and antioxidant status. Magnetized drinking water caused increase milk production, mutton, and wool in sheep not only that, but more weight gain in geese and egg production and hatchability in turkey can be achieved, and increasing in milk yields in dairy cows and ewes. It can be concluded that magnetic water treatment improved blood picture, biochemical parameters, semen quality, and antioxidant status in human and animals. So, magnetic water must be used to mitigate the harmful effects of drugs, toxins, and environmental pollutant on human and animals.

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“…These include effects on energy metabolism, specifically glycolysis, in restriction stressed rats [17]. In addition, we have also found that lipid peroxide level increase with the oxidizing agent was reduced by EF [19]. Therefore, we hypothesized that an EF might have an effect on the energy metabolism of organisms undergoing stress.…”

Section: Discussionmentioning

confidence: 94%

Effects of Exposure to a 50Hz Electric Field on Plasma Levels of Lactate, Glucose, Free Fatty Acids, Triglycerides and Creatine Phosphokinase Activity in Hind-Limb Ischemic Rats

Harakawa

Inoue

Hori

et al. 2005

The Journal of Veterinary Medical Science

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ABSTRACT. We previously reported that extremely low frequency electric fields (ELF-EFs) affect energy metabolism in stressed conditions. To further confirm this, the effect of exposure to ELF-EFs on the experimental ischemic rat was examined. The test was based on a comparison of rats treated with EF alone, ischemic surgery alone, the combination of EF with ischemic surgery, or no treatment (double sham). The EF condition used in this study was an alternating current of 50 Hz EF at 17 500 V/m intensity for 15 min per day. The exposure to EF in ischemic rats significantly decreased plasma levels of free fatty acids and triglycerides, compared to those of the no treatment or EF alone group. The plasma lactate levels of two ischemic groups peaked on experimental day-4 and gradually decreased until the end of the study. The changes in the lactate levels induced by ischemia did not show any difference between rats treated with ischemia alone or a combination of ischemia with an EF. Any changes in plasma levels of glucose and creatine phosphokinase activity were not influenced by EF treatment. These results indicate that the EF effect on glycolysis parameters, plasma lactate or glucose levels, does not appear in a highly stressed condition and that EF effects varied dependent on the condition of organism but ELF-EF used in this study have impact on lipid metabolism parameter in a hind-limb ischemic rat. However, further studies are needed to elucidate the association of ELF-EF with the lipid metabolism system. KEY WORDS: bioelectromagnetism, electric field, 50 Hz, ischemia, lipid metabolism.J. Vet. Med. Sci. 67(10): 969-974, 2005 The biological effects of an extremely low frequency electric field (ELF-EF) have become a matter of interest and debate as worldwide distribution of electricity, which markedly increased during the last half century, resulted in increased human exposure to electromagnetic fields (EMFs) [36]. Clinical techniques using electric fields (EFs) have been developed in disciplines such as complementary and integrative medical therapies [13][14][15][16]27]. In Japan, EF therapy has been utilized since 1972, when Hara et al. developed EF exposure equipment (Healthtron TM , Hakuju Institute for Health Science, Tokyo, Japan) [15], which was approved by the Ministry of Health, Labour and Welfare (Approval number 14700BZZ00904). Recently, the palliative effects of EF therapy on several types of pain (headache, stiff shoulders and stomachache) in over a thousand cases have been reported [16]. Publications explaining the mechanism(s) of the response of an exposure to an EF have suggested that either the EF-induced electric current or the perception of the EF through the skin surface acts as a trigger on cellular, humoral or behavioral responses [17, 18, 22-24, 32, 40, 44, 45].In a recent study, we reported evidence that an EF participates in the response to stress and also affects energy metabolism by suppressing the anabolism of lactate, not the acceleration of the catabolism of lactate [17]. However, ...

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Effects of a 50 Hz electric field on plasma lipid peroxide level and antioxidant activity in rats

Cited by 55 publications

References 24 publications

ELF-EMFs INDUCED EFFECTS ON CELL LINES: CONTROLLING ELF GENERATION IN LABORATORY

ELF-EMFs INDUCED EFFECTS ON CELL LINES: CONTROLLING ELF GENERATION IN LABORATORY

Biological Effects of Magnetic Water on Human and Animals

Effects of Exposure to a 50Hz Electric Field on Plasma Levels of Lactate, Glucose, Free Fatty Acids, Triglycerides and Creatine Phosphokinase Activity in Hind-Limb Ischemic Rats

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