Effects of a 2‐year behavioral weight loss intervention on sleep and mood in obese individuals treated in primary care practice

Abstract

ObjectiveTo examine the effect of weight loss on sleep duration, sleep quality, and mood in 390 obese men and women who received one of three behavioral weight loss intervention in the Practice-based Opportunities for Weight Reduction trial at the University of Pennsylvania (POWER-UP).MethodsSleep duration and quality were assessed at baseline and months 6 and 24 by the Pittsburgh Sleep Quality Index (PSQI) questionnaire and mood by the Patient Health Questionnaire-8 (PHQ-8). Changes in sleep and mood were examined according to treatment group and based on participants’ having lost ≥5% of initial weight vs <5%.ResultsThere were few significant differences between treatment groups in changes in sleep or mood. At month 6, however, mean (±SD) min of sleep increased significantly more in participants who lost ≥5% vs <5% (21.6±7.2 vs 1.2±6.0 min, p=0.0031). PSQI total scores similarly improved (declined) more in those who lost ≥5% vs <5% (−1.2±0.2 vs −0.4±0.2, p < 0.001), as did PHQ scores (−2.5±0.4 vs −0.1±0.3, p <0.0001). At month 24, only the differences in mood remained statistically significant (p < 0.05).ConclusionLosing ≥ 5% of initial weight was associated with short-term improvements in sleep duration and sleep quality, as well as favorable short- and long-term changes in mood.

The utility of weight loss medications after bariatric surgery for weight regain or inadequate weight loss: A multi-center study

“…It is well known that a number of antidepressants and antipsychotics are associated with significant weight gain [39–42]. Studies have reported associated improvements in mood after weight loss [43–46]. Therefore, we hypothesize that the need for these potential weight promoting medications was decreased in our cohort.…”

Preventing Weight Gain Improves Sleep Quality Among Black Women: Results from a RCT

“…(28) This evidence is largely derived from improvements in sleep post bariatric surgery;(46, 47) Only a few large-scale weight loss trials have shown that weight loss, among overweight and obese individuals, improves sleep outcomes. The POWER-UP(48) trial, which tested a behavioral weight loss intervention delivered in primary care, reported an increase in sleep duration, among participants who had lost ≥5% of their baseline body weight. Moreover, the Look AHEAD Study’s Sleep AHEAD(49) trial, widely considered one of the gold standard weight loss trials in participants with obstructive sleep apnea (OSA), showed that weight loss improved both sleep duration and quality.…”

Effect of 8-h time-restricted feeding on sleep quality and duration in adults with obesity

“…Obesity is associated with poor sleep quality and shorter sleep duration (Beccuti and Pannain 2011;Hasler et al 2004;Zimberg et al 2012). Weight loss by means of dietary restriction may help improve sleep quality and quantity (Alfaris et al 2015;Martin et al 2016). Timerestricted feeding (TRF) is an intermittent fasting weight-loss strategy, which involves an ad libitum feeding window of 4-10 h and a fasting window 14-20 h per day (Rothschild et al 2014).…”