Abstract:Ten-week-old C57B1/6J mice were given an intraperitoneal injection of 100 microCi radiostrontium (89Sr). One and two weeks following injection, the cellular composition of marrow and spleen was examined for cellularity, types of lymphoid cells, and incidences of small lymphocytes bearing sIgM, FcR, and CR. Strontium-89 treatment yielded a significant cell depletion in marrow, whereas spleen cellularity initially increased before returning to normal level in the second week. The increase in spleen cellularity w… Show more
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