Effects of 8 hemodynamic conditions on direct blood pressure values obtained simultaneously from the carotid, femoral and dorsal pedal arteries in dogs

Monteiro, Eduardo Raposo; Campagnol, Daniela; Bajotto, Gustavo Cancian; Simoes, C.; Rassele, Alice Corrêa

doi:10.1016/j.jvc.2013.07.002

Cited by 14 publications

(8 citation statements)

References 15 publications

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“…Based on the previous study [ 12 ], we measured the pulmonary artery pressure successfully according to the protocol. In briefly, we inserted 6F sheath guiding us into the femoral vein percutaneously, and then we can find the pulmonary artery.…”

Section: Methodsmentioning

confidence: 99%

Chronic obstructive sleep apnea accelerates pulmonary remodeling via TGF-β/miR-185/CoLA1 signaling in a canine model

Ding

Liu

et al. 2016

Oncotarget

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Chronic obstructive sleep apnea syndrome (OSAS) is considered to be associated with pulmonary diseases. However, the roles and mechanisms of OSA in pulmonary remodeling remain ambiguous. Thus, this study was aimed to elucidate the morphological and mechanical action of OSA in lung remodeling. In the present study, we employed a novel OSA model to mimic the OSA patient and investigate the role of OSA in pulmonary remodeling. We showed that pulmonary artery pressure of OSA group has no significant increased compared with the sham group. Nevertheless, we found that fibrotic tissue was predominantly located around the bronchi and vascular in the lung. Additionally, inflammatory cell infiltration was also detected in the peribonchial and perivascular space. The morphological change in OSA canines was ascertained by ultrastructure variation characterized by mitochondrial swelling, lamellar bodies degeneration and vascular smooth muscle incrassation. Moreover, sympathetic nerve sprouting was markedly increased in OSA group. Mechanistically, we showed that several pivotal proteins including collagen type I(CoLA1), GAP-43, TH and NGF were highly expressed in OSA groups. Furthermore, we found OSA could activated the expression of TGF-β, which subsequently suppressed miR-185 and promoted CoL A1 expression. This signaling cascade leads to pulmonary remodeling. In conclusion, Our data demonstrates that OSA can accelerate the progression of pulmonary remodeling through TGF-β/miR-185/CoLA1 signaling, which would potentially provide therapeutic strategies for chronic OSAS.

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Section: Methodsmentioning

confidence: 99%

Chronic obstructive sleep apnea accelerates pulmonary remodeling via TGF-β/miR-185/CoLA1 signaling in a canine model

Ding

Liu

et al. 2016

Oncotarget

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“…Third, previous studies indicate that the concentration of heparin does not affect the duration of arterial catheter patency within 24 h of arterial catheter placement in humans ( 23 ). Although some specific heparin concentrations are described in veterinary literature such as 1–2 IU/mL ( 9 ), 4 IU/mL ( 14 ), and 5 IU/mL ( 27 ), there is no consensus regarding the minimal heparin concentration to maintain the arterial catheter patency in dogs. In this study, the HS used had a concentration of 4 IU/mL, and this is considered much higher than that commonly used in human patients during direct arterial blood pressure measurements ( 2 ).…”

Section: Discussionmentioning

confidence: 99%

Heparinized Saline Solution vs. Saline Solution (0.9% Sodium Chloride) for the Maintenance of Dorsal Pedal Arterial Catheter Patency in Dogs Undergoing General Anesthesia: A Pilot Study

2020

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“…Essa diferença de local de mensuração por si pode resultar em valores de pressão arterial distintos. Estudos anteriores realizados em cães revelaram valores de pressão arterial diferentes quando mensurados simultaneamente em artérias localizadas em áreas distintas e as diferenças parecem ser maiores nos valores de PAS [5,6,9]. Segundo, os critérios utilizados para a validação de dispositivos de pressão arterial não invasiva são direcionados para a PAS e não para PAM e PAD [1].…”

Section: Análise Estatísticaunclassified

Evaluation of the Accuracy and Precision of the GE Dash 4000 Oscillometric Monitor for Blood Pressure Measurement in Anesthetized Female Dogs

Ferronatto

Monteiro

Correia

et al. 2018

Acta Scientiae. Vet.

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Background: Indirect measurement of arterial blood pressure, such as the oscillometric method, is the most commonly used in clinical practice of dogs and cats. This method measures blood pressure values that are estimates of direct (invasive) arterial blood pressure values. Oscillometric devices are easy to use even for non-experienced personnel. However, there is considerable variation in accuracy and precision of blood pressure values measured by different oscillometric monitors. The present study aimed to determine the accuracy and precision of the GE Dash 4000 oscillometric monitor for arterial blood pressure measurement in anesthetized female dogs. Materials, Methods & Results:Sixteen healthy adult female dogs received 0.3 mg/kg morphine as premedication and were anesthetized with propofol and isoflurane. A 22-gauge catheter was introduced into the dorsal pedal artery and connected to a rigid tubular system and a pressure transducer filled with heparinized solution to allow direct (invasive) measurement of systolic (SAP), mean (MAP) and diastolic arterial pressure (DAP). A blood pressure cuff was positioned proximal to the carpus and connected to the oscillometric device (GE-DASH 4000 monitor) in order to obtain indirect measurements of SAP, MAP and DAP. Cuff width was 40% of limb circumference. During anesthesia, invasive arterial blood pressure values were measured and recorded simultaneously with the oscillometric method. The Bland Altman method was used to evaluate agreement between the methods by calculating the bias (invasive -oscillometric) and limits of agreement. Percentages of differences between the methods with an error ≤ 10 mmHg and ≤ 20 mmHg were calculated. Results were compared with the criteria from the American College of Veterinary Internal Medicine (ACVIM) for validation of noninvasive blood pressure methods. Weight and age of dogs were 7.6 ± 2.2 kg and 20 ± 17 months, respectively. A total of 195 pairs of measurements were obtained from 16 animals. Of these pairs, 146 were classified as normotension (SAP: 90 to 140 mmHg), 28 as hypertension (SAP > 140 mmHg) and 21 as hypotension (SAP < 90 mmHg). Bias values ± SD (95% limits of agreement) were: SAP, 5.0 ± 16.5 mmHg (-27.3 to 37.4 mmHg); MAP, -3.4 ± 14.3 mmHg (-31.4 to 24.6 mmHg); and DAP, 4.2 ± 11.8 mmHg . According to the ACVIM criteria, maximum values accepted for bias (± SD) are 10 ± 15 mmHg. Percentages of differences ≤ 10 mmHg and ≤ 20 mmHg were: SAP, 41% and 80%; MAP, 54% and 84%; and DAP, 64% and 91%. ACVIM recommendations are ≥ 50% for errors within 10 mmHg and ≥ 80% for errors within 20 mmHg. Discussion: MAP and DAP values obtained by the GE-DASH 4000 monitor matched the ACVIM criteria for validation of noninvasive methods. Conversely, SAP values did not meet all the criteria, and were not considered reliable. Limitations of the study include: a) most dogs were of low weight; b) the ACVIM criteria refer to SAP measurements, but in the present study, the same criteria were applied to MAP and DAP measurements; c) the majority of ob...

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Effects of 8 hemodynamic conditions on direct blood pressure values obtained simultaneously from the carotid, femoral and dorsal pedal arteries in dogs

Cited by 14 publications

References 15 publications

Chronic obstructive sleep apnea accelerates pulmonary remodeling via TGF-β/miR-185/CoLA1 signaling in a canine model

Chronic obstructive sleep apnea accelerates pulmonary remodeling via TGF-β/miR-185/CoLA1 signaling in a canine model

Heparinized Saline Solution vs. Saline Solution (0.9% Sodium Chloride) for the Maintenance of Dorsal Pedal Arterial Catheter Patency in Dogs Undergoing General Anesthesia: A Pilot Study

Evaluation of the Accuracy and Precision of the GE Dash 4000 Oscillometric Monitor for Blood Pressure Measurement in Anesthetized Female Dogs

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