Effects of 7S and 11S on the intestine of weaned piglets after injection and oral administration of soybean antigen protein

Abstract

Soybeans are used increasingly in food products because of their health benefits. In this study, we investigated the effect of soybean antigen protein on weaned piglet intestine. Seventy piglets were randomly divided into seven groups with 10 piglets each. At 7 and 14 days of age, groups A–C were injected with saline, and D–G were intramuscularly injected with or orally administered 7S or 11S. Groups B–G were artificially sensitized by dietary 7S or 11S. At 27 days, the small intestinal tissues were collected to determine levels of histamine, sIgA protein, and IgA mRNA. Histamine in B–G was significantly decreased in the duodenum and ileum. Moreover, sIgA expression was higher in all groups than in A, with B/C>D–G and F/G>D/E; the trend in IgA expression was similar. Collectively, these results indicated that soybean antigen protein‐immunizing agents decrease sIgA and IgA levels. Additionally, the effect of injection immunization occurred prior to that of oral immunization.

Effects of Supplementing Intestinal Autochthonous Bacteria in Plant-Based Diets on Growth, Nutrient Digestibility, and Gut Health of Bullfrogs (Lithobates catesbeianus)

“…et al, 2017;Naylor et al, 2021). However, due to their general drawbacks such as low palatability, imbalanced amino acid profile, and presence of anti-nutritional factors (Liu et al, 2019;Peng et al, 2019;Yao et al, 2019), an excess proportion of plant proteins in diets usually induce immune dysfunction, gut inflammation, and subsequent growth inhibition in animals (Sahlmann et al, 2013;Wang et al, 2020).…”

Antigenic activity and epitope analysis of β‐conglycinin hydrolyzed by pepsin

“…Reports indicate that 5–8% of all infants and 2% of all adults in the USA and Europe are allergic to soybean protein 14 . In the feed industry, hypersensitivity caused by soybean antigens is fairly prevalent among young mammals 15–18 . Recent research has therefore focused on the antigenic protein components of soybean and methods to eliminate their antigenicity.…”

“…14 In the feed industry, hypersensitivity caused by soybean antigens is fairly prevalent among young mammals. [15][16][17][18] Recent research has therefore focused on the antigenic protein components of soybean and methods to eliminate their antigenicity.…”