Effects of 25-hydroxycholecalciferol on performance, gut health, and bone quality of broilers fed with reduced calcium and phosphorus diet during Eimeria challenge

Lopes, T.S.B.; Shi, H.; White, D.; Araújo, I.C.S.; Kim, W.K.

doi:10.1016/j.psj.2023.103267

Cited by 5 publications

(3 citation statements)

References 73 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, VitD 3 increases the Ca + ions transport from the apical to the basal membrane, being a coordinator of Ca uptake from the intestinal lumen into the plasma (Fatemi et al, 2021). However, other scenarios such as dietary Ca and P levels (Brito et al, 2010;Gómez-Verduzco et al, 2013) and protozoan (Shanmugasundaram et al, 2019;Lopes et al, 2024) and bacterial challenges (Morris et al, 2014;Nunes et al, 2020) can change the dietary vitamin D level required to maintain health and performance.…”

Section: Discussionmentioning

confidence: 99%

“…On the other hand, excess VitD 3 can cause bone diseases, such as osteopetrosis and osteochondrosis or TD (Aguirre et al, 2005). Therefore, investigations into VitD 3 levels that promote the best performance of broilers have been the subject of studies for several years (Edwards et al, 1992;Fritts and Waldroup, 2003;Castro et al, 2018;Lopes et al, 2024). However, the level of VitD 3 that promotes the best performance, in terms of feed efficiency and performance, will not always promote bone health (Leyva-Jimenez et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Performance and bone health of broilers reared under artificial lighting and supplemented with different levels of vitamin D3

Lopes,

Vasconcelos,

Costa

et al. 2024

Revista Brasileira De Zootecnia

Self Cite

View full text Add to dashboard Cite

This study aimed to investigate the effects of different levels of vitamin D 3 in broiler diets on performance and bone health. A total of 360 one-day old male Cobb500 ® broiler chicks were subjected to five treatments of different levels of vitamin D 3 in diets during two rearing phases: 0 IU/kg in both phases; 625 IU/kg in starter and 500 IU/kg in grower phase (25% of commercial inclusion); 1,250 IU/kg in starter and 1,000 IU/kg in grower phase (50% of commercial inclusion); 1,875 IU/kg in starter and 1,500 IU/kg in grower phase (75% of commercial inclusion); and 2,500 IU/kg in starter and 2,000 IU/kg in grower phase (100% of commercial inclusion). The traits studied weekly were feed intake, body weight, feed conversion, and viability. At 21 and 35 days of age, tibiae and femurs were removed, dissected, and evaluated for dry matter (DM), ash (%MM), calcium (%Ca), phosphorus (%P) and breaking strength. At 35 days of age, the bones were subjected to histopathological analysis for macroand microscopic morphological evaluation. Data were subjected to regression analysis, using α = 0.05. The variables of percentage %MM, %Ca, %P, and breaking strength experienced a positive linear effect up to the supplementation levels of approximately 25% of inclusion. The histopathological analysis found that the group that received the diet with 100% inclusion of vitamin D 3 presented lesions compatible with osteopetrosis and tibial dyschondroplasia. The observed results showed that for isonutritive diets, reduced levels of vitamin D 3 guaranteed performance during the evaluated period while the use of 100% of vitamin D 3 , as commonly used, can cause bone diseases and harm the welfare of broilers.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Performance and bone health of broilers reared under artificial lighting and supplemented with different levels of vitamin D3

Lopes,

Vasconcelos,

Costa

et al. 2024

Revista Brasileira De Zootecnia

Self Cite

View full text Add to dashboard Cite

show abstract

“…In broilers challenged with either E. maxima or mixed Eimeria spp. and fed reduced calcium/phosphorus diets, supplementation of 25(OH)D 3 at the rate of either 3000 IU/kg or 4000 IU/kg has been shown to improve bone mineralization [83,84,93]. Furthermore, in laying hens challenged with lipopolysaccharides, 25(OH)D 3 supplementation improved egg production by improving follicular development and oocyte maturation by increasing the expression of VDR in oocytes, maintaining the plasma estradiol/progesterone and luteinizing hormone levels [94][95][96][97].…”

Section: Vaccinationmentioning

confidence: 99%

Coccidiosis in Egg-Laying Hens and Potential Nutritional Strategies to Modulate Performance, Gut Health, and Immune Response

Sharma,

Kim

2024

Animals

Self Cite

View full text Add to dashboard Cite

Avian coccidiosis, despite advancements in management, nutrition, genetics, and immunology, still remains the most impactful disease, imposing substantial economic losses to the poultry industry. Coccidiosis may strike any avian species, and it may be mild to severe, depending on the pathogenicity of Eimeria spp. and the number of oocysts ingested by the bird. Unlike broilers, low emphasis has been given to laying hens. Coccidiosis in laying hens damages the gastrointestinal tract and causes physiological changes, including oxidative stress, immunosuppression, and inflammatory changes, leading to reduced feed intake and a drastic drop in egg production. Several countries around the world have large numbers of hens raised in cage-free/free-range facilities, and coccidiosis has already become one of the many problems that producers have to face in the future. However, limited research has been conducted on egg-laying hens, and our understanding of the physiological changes following coccidiosis in hens relies heavily on studies conducted on broilers. The aim of this review is to summarize the effect of coccidiosis in laying hens to an extent and correlate it with the physiological changes that occur in broilers following coccidiosis. Additionally, this review tries to explore the nutritional strategies successfully used in broilers to mitigate the negative effects of coccidiosis in improving the gut health and performance of broilers and if they can be used in laying hens.

show abstract

Interactive effects of calcium, phosphorus, and exogenous phytase on growth performance and bone ash in broilers under Eimeria or necrotic enteritis infections: a systemic review and meta-analysis

Shi,

Wang,

Kim

2024

Journal of Applied Poultry Research

View full text Add to dashboard Cite

Effects of 25-hydroxycholecalciferol on performance, gut health, and bone quality of broilers fed with reduced calcium and phosphorus diet during Eimeria challenge

Cited by 5 publications

References 73 publications

Performance and bone health of broilers reared under artificial lighting and supplemented with different levels of vitamin D3

Performance and bone health of broilers reared under artificial lighting and supplemented with different levels of vitamin D3

Coccidiosis in Egg-Laying Hens and Potential Nutritional Strategies to Modulate Performance, Gut Health, and Immune Response

Interactive effects of calcium, phosphorus, and exogenous phytase on growth performance and bone ash in broilers under Eimeria or necrotic enteritis infections: a systemic review and meta-analysis

Contact Info

Product

Resources

About