Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on spontaneous movement of human neuroblastoma cells

Abstract

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Emerging therapeutic targets for neuroblastoma

“…Another NP approach using a combination of semi-synthetic cytotoxic retinoid and anti-angiogenic lenalidomide displayed excellent in vitro cytotoxicity and in vivo efficacy [165]. MXD3antisense oligonucleotide-loaded SPIONPs delivered to NB without toxicity indicated its benefit as dose-reducing agent for CT [166]. In an interesting strategy, a bismuth selenide NPs core shelled with silver was coupled with RNA 3-way junction: one leg attached to the NP, the second harbored a cell-penetrating RNA+fluorescence tag, and the third was designed to target miR-17 and RA release [58].…”

Targeting AhR as a Novel Therapeutic Modality against Inflammatory Diseases

“…Further, the physiological function of AhR has gained a wealth of attention more recently. Not only does it interact with signaling pathways involved in cell proliferation and cell cycle [ 45 , 46 ], cytokine secretion [ 47 ], cell adhesion and cell migration [ 48 ], but specifically in mammals, AhR seems to have been involved in the development and functions of the immune system and thus is present in a variety of immune cell types [ 35 , 37 , 49 ].…”