Effects of 17β-estradiol, Interleukin-1β, and Human Chorionic Gonadotropin on Activity and mRNA Expression of Plasminogen Activators in Porcine Endometrial Cells
Abstract:This study aimed to investigate changes in the activity and mRNA expression of
plasminogen activators (PAs) induced by 17β-estradiol (E2),
human chorionic gonadotropin (hCG), and interleukin-1β (IL-1β) in
porcine endometrial cells. Endometrial cells were isolated from the epithelium
and cultured to 80% confluence. They were then treated for 24 h with
E2 (0.2, 2, 20, and 200 ng/mL), IL-1β (0.1, 1, 10, and 100
ng/mL), and hCG (0.5, 1, 1.5 and 2 IU/mL). mRNA expressions of urokinase-type
(uPA) and tissue-type (tP… Show more
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