Effects Different Levels of Nanoparticles Chromium Picolinate Supplementation on Growth Performance, Mineral Retention, and Immune Responses in Broiler Chickens

Abstract

This study was conducted to investigate the effects of different levels nanoparticles of chromium picolinate (NanoCrPic) on the performance, immune responses, mineral retention, and tissues accumulation of chickens. A total of 180 broilers were randomly allocated into 0 (control), 500 ppb (µg kg -1 ) Cr and 3000 ppb Cr groups with 6 replicates (10 birds/pen) for a 35-day experiment, the Cr is nanoparticles of chromium picolinate (NanoCrPic). In addition, 36 birds were used for metabolic experimental investigation. The results of the experimentation indicated that there were no significant differences in average body weight gain between groups, but feed conversion ratio (FCR) in 3000 ppb group was better than control group during 1-21 days. The carcass yields slightly lower in 3000 ppb group than control (p<0.1). Retention ratio of Zn, Fe, Mn, Ca, and P were significantly (p<0.05) increased in the 500 ppb Cr group. The addition of NanoCrPic caused increased mineral concentrations, such as Cr, Ca and P in the subjects' livers. Furthermore, the addition of NanoCrPic significantly increased lymphocytes and decreased both heterophils and H/L ratio (p<0.05). The ND (Newcastle disease) antibody titer was not affected in the broilers. In conclusion, supplemental NanoCrPic improved the retention of Zn, Fe Ca, notably it increased the concentration of Cr and Ca in the liver, and also increased the number of lymphocytes in broiler chickens.

Effect of Different Levels of Nanoparticles Chromium Picolinate Supplementation on Performance, Egg Quality, Mineral Retention, and Tissues Minerals Accumulation in Layer Chickens

“…In addition, Cr has been shown that supplemental chromium led to increased Cr and Zn in serum, liver, kidney and longissimus muscle of laying hens and Japanese quails (Sahin et al, 2002a;Sahin et al, 2002b), but Fe concentrations were not affected in Japanese quails. Our previous study also indicated that NanoCrPic supplementation in broilers diet increased the concentration of Cr and Ca in the liver (Sirirat et al, 2012). Those reports were agreed with our results.…”

“…Our results are in agreement with the results of Sahin and Sahin (2002), who reported that the retention of Zn was improved by supplemental Cr and ascorbic acid. In our previous study with broiler also indicated that supplemental NanoCrPic improved the retention of Zn (Sirirat et al, 2012), which may be owing to the Zn excretion being reduced in NanoCrPic group. Amatya et al (2004) also reported that supplemental Cr had effect on the retention of Zn and Mn in broilers.…”

Effect of dietary supplementation of vitamin E, zinc, and chromium supplementation on growth performance and hematological characteristics of broiler chickens

“…They however observed no statistically significant differences (p>0.05) on monophil, esonophil and basophil percentages between treatment groups supplemented with vitamin E and control groups. Sirirat et al (2012), in a study conducted to investigate the effects of different levels nanoparticles of chromium picolinate (NanoCrPic) on the performance, immune responses, mineral retention, and tissues accumulation of chickens reported significant increase in lymphocytes (p<0.0004) as the level of Cr supplementation increased to 3000ppb. Zha et al (2008) observed lympho proliferative response in rats feed supplementary Cr of 150, 300 and 450 ppb.…”

Krom (III) Pikolinat ve Krom (III) Pikolinat Nanopartikül Katkısının Siklik Isı Stresine Maruz Kalan Broiler Civcivlerde Büyüme Performansı, Organ Ağırlığı ve Bağışıklık Fonksiyonları Üzerine Etkileri

“…Recently, nanotechnology has rapidly been developing different scientific areas and nanoscale of materials has interested extention because nano-formulation particulates exhibit novel distinguishing quality such as a size, shape, large surface area, high surface activity, high catalytic efficiency and strong adsorbing ability [21] . Limited published data in various experimental conditions implicated higher absorption and bioavailability of chromium nanoparticles [22][23][24] . Previous researches have shown that chromium nanoparticles had beneficial properties on growth performance, body composition, as well as augmented tissue concentrations of Cr in selected muscles [25] and serum [24] .…”