Effects comparison between the secondary nanoplastics released from biodegradable and conventional plastics on the transfer of antibiotic resistance genes between bacteria

Liu, Xiaomei; Wang, Xiaolong; Wang, RenJun; Guo, Shengli; Ahmad, Shakeel; Yao, Song; Gao, Peike; Chen, Junfeng; Liu, Chunchen; Ding, Ning

doi:10.1016/j.envpol.2022.120680

Cited by 12 publications

(3 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…22,23 They also significantly increase the transfer efficiency of antibiotic-resistance genes (ARGs). 24 Ortega et al found that MPs can act as carriers of coexisting contaminants in the atmosphere, yielding a better understanding of the dangers and risks of atmospheric and airborne MPs or NPs, their impacts, cotransport capacity, and interaction with the environment. 25…”

Section: Effects Of Mps/nps On the Respiratory Pathwaymentioning

confidence: 99%

Microplastics exposure and immunologic response

Urrutia-Pereira,

Guidos-Fogelbach,

Chong-Neto

et al. 2023

Allergol Immunopathol

View full text Add to dashboard Cite

Objective: To assess the impact of microplastics (MPs) on human health. Data Source: The authors conducted a non-systematic review of articles published in English, Portuguese, French, and Spanish in the last decade in the following databases: PubMed, Google Scholar, EMBASE, and SciELO. The keywords used were: microplastics OR nanoplastics OR marine litter OR toxicology OR additives AND human health OR children OR adults. Data summary: MPs are a group of emerging contaminants that have attracted scientific interest and societal attention in the last decade due to their ubiquitous detection in all environments. Humans can primarily be exposed to MPs and nanoplastics via oral and inhalation routes, but dermal contact cannot be overlooked, especially in young children. The possible toxic effects of plastic particles are due to their potential toxicity, often combined with that of leachable additives and adsorbed contaminants. Conclusions: Unless the plastic value chain is transformed over the next two decades, the risks to species, marine ecosystems, climate, health, economy, and communities will be unmanageable. However, along with these risks are the unique opportunities to help transition to a more sustainable world.

show abstract

Section: Effects Of Mps/nps On the Respiratory Pathwaymentioning

confidence: 99%

Microplastics exposure and immunologic response

Urrutia-Pereira,

Guidos-Fogelbach,

Chong-Neto

et al. 2023

Allergol Immunopathol

View full text Add to dashboard Cite

show abstract

“…Moreover, the micro/nanoplastics inevitably undergo aging processes, which can be caused by mechanical fragmentation, high temperature, UV degradation, and biological digestion in the environment. 17 The aging process can significantly alter the surface properties of micro/ nanoplastics, such as oxygen content, molecular weight, and surface appearance, 18 and thereby affects the adsorption capacity toward other chemicals and pollutants, 19 such as heavy metals, 18 organic contaminants (phenanthrene), 20 antibiotics, 21 and humic acid. 22 Therefore, aged micro/ nanoplastics are predicted to change the environmental behavior of the coexisting pollutants and are likely to alter the toxic effects induced by micro/nanoplastics or the pollutants.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Hasegawa et al proved that plastic additives carried by polyethylene microplastics can accumulate in Myoxocephalus brandti organs, while Stienbarger et al prepared polyethylene microplastics loaded with phenanthrene and found that the absorbed pollutants did not increase the polyethylene microplastics toxicity to Centropristis striata . Moreover, the micro/nanoplastics inevitably undergo aging processes, which can be caused by mechanical fragmentation, high temperature, UV degradation, and biological digestion in the environment . The aging process can significantly alter the surface properties of micro/nanoplastics, such as oxygen content, molecular weight, and surface appearance, and thereby affects the adsorption capacity toward other chemicals and pollutants, such as heavy metals, organic contaminants (phenanthrene), antibiotics, and humic acid .…”

Section: Introductionmentioning

confidence: 99%

Microcystins-Loaded Aged Nanoplastics Provoke a Metabolic Shift in Human Liver Cells

Shen

Salam

et al. 2023

Environ. Sci. Technol.

View full text Add to dashboard Cite

Studies concerning the toxicity of pollutant-loaded nanoplastics (NPs) toward humans are still in their infancy. Here, we evaluated the adsorption of microcystins (MCs) by pristine and aged polystyrene nanoplastics (PSNPs), prepared MCs-loaded aged PSNPS (1, 5, 10, 15, and 19 μg/mg), and systematically mapped the key molecular changes induced by aged and MCs-loaded PSNPs to human hepatoblastoma (HepG2) cells. According to the results, MC-LR adsorption is increased 2.64-fold by aging, and PSNP accumulation is detected in HepG2 cells. The cytotoxicity of the MC-LR-loaded aged PSNPs showed a positive relationship with the MC-LR amount, as the cell viability in the 19 μg/mg loading treatment (aPS-MC19) was 10.84% lower than aged PSNPs; meanwhile, more severe oxidative damage was observed. Primary approaches involved stressing the endoplasmic reticulum and reducing protein synthesis that the aged PSNPs posed for HepG2 cells, while the aggravated cytotoxicity in aPS-MC19 treatment was a combined result of the metabolic energy disorder, oxidative damage, endoplasmic reticulum stress, and downregulation of the MC-LR target protein. Our results confirm that the aged PSNPs could bring more MC-LR into the HepG2 cells, significantly interfere with biological processes, and provide new insight into deciphering the risk of NPs to humans.

show abstract