Effectivenesss of some Feed Additives for Detoxification of Aflatoxin B1 in Laying Hens

A consortium of detoxifying bacteria mitigates the aflatoxin B1 toxicosis on performance, health, and blood constituents of laying hens

“…Our results of ameliorating the effects of AFB1 on BW and higher EP, EM, and EW are also in agreement with the study in which AFB1-detoxifying agents (hydrated sodium calcium aluminosilicate ( HSCAS ), mannan oligosaccharides ( MOS ), and Lactobacillus acidophilus ( LA )) significantly mitigated the deleterious effects of AFB1 on final BW and BW gain of laying hens and increased EP, EW, and EM ( Sherif et al, 2018 ). Similar to our study, their result of FCR was also improved.…”

“…A study using feed additives as detoxifiers such as HSCAS, MOS, and LA along with AFB1 reflected an increase in yolk weight, shell percentage, shell thickness, and yolk color ( Sherif et al, 2018 ) which are partially in agreement with our results in which no significant differences were observed in yolk weight and shell thickness but MF group produced a significant rise in shell percentage, and an increase in yolk weight was manifested in only PC treatment. These discrepancies might be owing to the concentration and the type of detoxifiers.…”

“…The result of increased serum globulin by the treatments in the current study is in line with the study in laying hens offered AFB1 and supplementing HSCAS, MOS, and LA as detoxifiers ( Sherif et al, 2018 ) while the results of serum albumin, total protein, cholesterol, and uric acid were different, in which a drop in albumin level and a rise in uric acid and no significant difference in total protein and cholesterol were observed. A reduction in serum glucose, which is shown by PC group in the current trial, might be associated with the nephrotoxic effects of AFs, indicating a damage to the liver cells ( Manafi, 2018 ), which is mitigated by other treatments.…”

“…Furthermore, a linear correlation is reported between poor egg quality, which exhibited in PC group in the current trial, and consuming AF ( Manafi, 2018 ). The yolk color variation, as shown in the current study, is postulated to be associated with AFB1 intervention with lipid metabolism, deposition, and absorption of carotenoid in yolk ( Sherif et al, 2018 ). In general, a disruption by AFB1 in reproductive performance and physiological systems has already been reported by Bagherzadeh Kasmani et al (2018) .…”

“… Manafi (2018) has also found a lighter EW by AFB1 and heavier EW in a group receiving a toxin-binder (NBM) along with AFB1. Probiotics are believed to alter microbiota populations and the pH of GIT in favor of augmenting the activity of intestinal enzymes and nutrients’ digestibility, leading to an increase in ADFI and altering metabolic profile ( Sherif et al, 2018 ).…”