Rare ILD/DPLD 2019
DOI: 10.1183/13993003.congress-2019.oa2142
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Effectiveness of various therapy regimens for patients with pulmonary Langerhans cell histiocytosis during long-term follow-up

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“…No association was identified between the presence of this mutation and disease presentation or outcome, in contrast to what has been reported in paediatric LCH populations who have higher risk of organ involvement. Two large retrospective studies, one from Russia and one from Poland, found a lack of response to corticosteroid therapy in LCH; conversely, cladribine was reported to be associated with 88-100% stabilisation/regression of the disease [69,70].…”
Section: Rare Ilds/dpldsmentioning
confidence: 98%
“…No association was identified between the presence of this mutation and disease presentation or outcome, in contrast to what has been reported in paediatric LCH populations who have higher risk of organ involvement. Two large retrospective studies, one from Russia and one from Poland, found a lack of response to corticosteroid therapy in LCH; conversely, cladribine was reported to be associated with 88-100% stabilisation/regression of the disease [69,70].…”
Section: Rare Ilds/dpldsmentioning
confidence: 98%