Effectiveness of Sildenafil in Pulmonary Hypertension Secondary to Valvular Heart Disease: A Systematic Review and Meta-Analysis

Ghaffar, Farizan Abdul; Redzuan, Adyani Md; Makmor-Bakry, Mohd

doi:10.51847/tcievrcfgf

Cited by 4 publications

(2 citation statements)

References 40 publications

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“…Rivaroxaban is taken for three weeks in doses of 15 mg twice daily, then 20 mg once daily. Treatment lasts for six months, but if a temporary major risk factor is present, it may be reduced to three months, or it may last indefinitely there are persistent major risk factors (e.g., cancer, recurrent unprovoked pulmonary embolism) (EINSTEIN-PE Investigators et al, 2012;Ghaffar et al, 2021).…”

Section: Anticoagulationmentioning

confidence: 99%

Review on Pulmonary Embolism Diagnosis and Management Approach

Elsayed¹,

Humaidan²,

Hawsawi³

et al. 2022

World J Environ Biosci

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A frequent illness, pulmonary embolism can cause considerable morbidity and mortality. Certain inherited and acquired risk factors predispose vulnerable individuals, and the clinical situation can arouse suspicion. Studies involving people who had non-alcoholic fatty liver disease were sought after in the Medline, Pubmed, Embase, NCBI, and Cochrane databases. Analysis was done on incidence, etiology, and treatment options. Because PE presents differently in each patient, it is important to take that into account. The accuracy of the diagnosis decreases with patient age. The diagnosis is difficult because of comorbidities like bronchopneumonia, Chronic Obstructive Pulmonary Disease (COPD), asthma, or chronic fibrosing pulmonary processes The clinical diagnosis of pulmonary embolism is extremely ambiguous because none of the symptoms or signs related to pulmonary embolism are distinctive and can all be caused by other cardiorespiratory illnesses. Patients who have an abnormal perfusion lung scan require more sophisticated care. It can be difficult to diagnose conditions when they have comorbid conditions like bronchopneumonia, chronic obstructive pulmonary disease (COPD), asthma, or chronic fibrosing pulmonary processes. The diagnosis of PE can be made quickly in patients who have DVT, though. Thrombosis of the renal, iliac, and inferior vena cava veins, as well as DVT, were the main causes of up to 85% of PE cases.

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Section: Anticoagulationmentioning

confidence: 99%

Review on Pulmonary Embolism Diagnosis and Management Approach

Elsayed¹,

Humaidan²,

Hawsawi³

et al. 2022

World J Environ Biosci

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“…Ischemic heart disease is defined by decreased cardiac blood flow, which throws off the balance between the oxygen supply and demand in the myocardium [1][2][3]. Most typically, coronary artery disease (CAD), caused by atherosclerotic spasm or blockage of the epicardial coronary arteries, or microvascular dysfunction, is the underlying clinical mechanism.…”

Section: Introductionmentioning

confidence: 99%

The Role of Cold Exposure on Ischemic Heart Disease: A Systematic Review

Sabah¹,

Alarim²,

Alarim³

2022

Pharmacophore

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The primary aim of this systematic review is to examine the published research on the connection between cold exposure and ischemic heart disease (IHD). We conducted a systematic search through PubMed, Web of Science, Science Direct, EBSCO, and the Cochrane library. Using Rayyan QCRI, study articles were first screened by title and abstract before a full-text analysis was implemented. A total of six studies with 281979 patients were included. We comprised various cold events, including cold work environments among workers, cold spells, usual cold exposure, and prolonged extreme cold. Two studies reported that cold exposure among workers and the general population increases the risk of mortality rate due to myocardial infarction (MI). In CAD patients, prolonged severe cold exposure worsens coronary events (signs and symptoms). This comprehensive review indicated that exposure to the cold increased the risk of MI-related death in both workers and the general population. Furthermore, continuous exposure to extremely cold conditions makes coronary events worse in people with CAD.

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