Effectiveness of Secondary Alveolar Bone Graft on Canine Eruption: Systematic Review

Abstract

There are controversies related to the effects of bone grafts on tooth eruption and impaction in patients with cleft lip and palate. The aim of this systematic review was to evaluate the effectiveness of bone grafting on eruption of canines in patients with unilateral cleft lip and palate (UCLP). An electronic search was conducted in six electronic databases and gray literature, without limitations on year of publication or language. The primary outcome was the increase in rate of canine eruption; the secondary outcomes were success of the bone graft, canine impaction due to agenesis of the lateral incisor, and effect of orthodontic treatment before and after bone grafting. The risk of bias was analyzed by means of the tool Cochrane risk of bias in nonrandomized controlled trials (NRCTs) of interventions (ROBINS-I). The certainty of the evidence was assessed for outcomes reported through a narrative synthesis using grading of recommendations, assessment, development and evaluation (GRADE) approach. Four NRCTs were included, with a total of 360 patients, 283 UCLP and 77 bilateral cleft lip and palate (BCLP). The studies reported association between the increase in the rate of tooth eruption and bone graft with very low certainty of evidence, and greater experience of surgical success, with low certainty of evidence. The majority of the studies found an association between increase in the rate of canine impaction and agenesis of the lateral incisor, with very low certainty of evidence. There was very low certainty of the efficacy of secondary alveolar bone grafting for increasing the rates of eruption and reducing impaction of the maxillary canine.

Effect of Yellow Propolis on Biocompatibility of Cements: Morphological and Immunohistochemistry Analysis

“…Its biological effect has the potential to inflammatory control and repair of gingival tissues in different clinical conditions. 46 47 Clinical experiments with humans could check the efficacy of what appears to be a highly promising method for obtaining an antibacterial GIC.…”

A CBCT Based Assessment of Canine Eruption and Development Following Alveolar Bone Grafting in Patients Born With Unilateral Cleft lip and/or Palate

“…However, other studies have instead found a positive relationship between agenesis of the lateral incisor and canine impaction, confirming the effect of the lateral incisor in guiding the canine to the normal eruption path (Enemark et al, 2001; Simões Holz et al, 2018). A recent systematic review found that there is very low certainty of evidence confirming the association between the agenesis of the lateral incisors and the impaction of the canines (Lacerda-Santos et al, 2021).…”

Pilot study of factors contributing to canine impaction after secondary alveolar bone grafting in unilateral cleft lip and palate patients

“…They didn’t find any association between congenital absence of lateral incisors and canine root completion, canine eruption failure. Meanwhile, some studies found an association between increase in the rate of canine impaction and agenesis of lateral incisor, with very low certainty of evidence 12 . Some studies mentioned insufficient arch space of CLP patients is proposed to be associated with canine impactions 13 others mentioned there is no relationship between canine impaction and dental crowding 14 .…”