Effectiveness of scheduled postoperative intravenous acetaminophen for colon cancer surgery pain

Horita, Eiji; Takahashi, Yûji; Takashima, Kojiro; Saito, Kenichiro; Takashima, Yoshinori; Munemoto, Yoshinori

doi:10.1186/s40780-018-0115-1

Cited by 3 publications

(2 citation statements)

References 8 publications

(11 reference statements)

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“…Caution is needed in the frail patient, especially in the context of coexisting liver disease. For an amount of acetaminophen infusion sufficient to ensure a significant reduction in postoperative pain compared with groups without treatment ( P = 0.008), an increase in alanine aminotransferase has been observed ( P = 0.043) [ 50 ].…”

Section: Methodsmentioning

confidence: 99%

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Postoperative pain management in non-traumatic emergency general surgery: WSES-GAIS-SIAARTI-AAST guidelines

Coccolini

Corradi²,

Sartelli

et al. 2022

World J Emerg Surg

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Background Non-traumatic emergency general surgery involves a heterogeneous population that may present with several underlying diseases. Timeous emergency surgical treatment should be supplemented with high-quality perioperative care, ideally performed by multidisciplinary teams trained to identify and handle complex postoperative courses. Uncontrolled or poorly controlled acute postoperative pain may result in significant complications. While pain management after elective surgery has been standardized in perioperative pathways, the traditional perioperative treatment of patients undergoing emergency surgery is often a haphazard practice. The present recommended pain management guidelines are for pain management after non-traumatic emergency surgical intervention. It is meant to provide clinicians a list of indications to prescribe the optimal analgesics even in the absence of a multidisciplinary pain team. Material and methods An international expert panel discussed the different issues in subsequent rounds. Four international recognized scientific societies: World Society of Emergency Surgery (WSES), Global Alliance for Infection in Surgery (GAIS), Italian Society of Anesthesia, Analgesia Intensive Care (SIAARTI), and American Association for the Surgery of Trauma (AAST), endorsed the project and approved the final manuscript. Conclusion Dealing with acute postoperative pain in the emergency abdominal surgery setting is complex, requires special attention, and should be multidisciplinary. Several tools are available, and their combination is mandatory whenever is possible. Analgesic approach to the various situations and conditions should be patient based and tailored according to procedure, pathology, age, response, and available expertise. A better understanding of the patho-mechanisms of postoperative pain for short- and long-term outcomes is necessary to improve prophylactic and treatment strategies.

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Section: Methodsmentioning

confidence: 99%

“…49 ICU Department, P. Giaccone Hospital, Palermo, Italy. 50 ICU Department, San Martino Hospital, Genoa, Italy. 51 General, Emergency and Trauma Surgery Department, Vicenza Hospital, Vicenza, Italy.…”

Section: Abbreviationsmentioning

confidence: 99%

Postoperative pain management in non-traumatic emergency general surgery: WSES-GAIS-SIAARTI-AAST guidelines

Coccolini

Corradi²,

Sartelli

et al. 2022

World J Emerg Surg

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2018

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Efficacy of Oral Gabapentin and Acetaminophen for Postoperative Analgesia in Anorectal Surgery: A Fuzzy Logic Evaluation

Ishagh Hosseini,

Derakhshan Barjoei,

Bahadorzadeh

et al. 2024

Middle East J Dig Dis

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Background: The present study attempted to evaluate the effect of oral gabapentin and acetaminophen for postoperative analgesia in anorectal surgery. Methods: This double-blind clinical trial was carried out on 144 patients who were candidates for anorectal surgery. The patients were randomly assigned into three groups of control, acetaminophen 500 mg, and gabapentin 300 mg for two hours before the surgery. Data on pain severity based on the visual analog scale (VAS) were evaluated and analyzed. Results: The results of the current study indicated that in patients taking acetaminophen and gabapentin tablets before surgery, the amount of postoperative pain decreased, and the amount of decrease in postoperative pain in the patients who received acetaminophen and gabapentin tablets compared with the placebo group was significant (P<0.001). Also, an evaluation was done using a proposed fuzzy logic model. Conclusion: Taking acetaminophen and gabapentin tablets one hour before the operation causes a significant reduction in postoperative pain in patients who are candidates for anorectal surgery. The results are promising and encourage one to pay attention to more studies with the goal of possibly using them as a decision-support model in the future.

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Effectiveness of scheduled postoperative intravenous acetaminophen for colon cancer surgery pain

Cited by 3 publications

References 8 publications

Postoperative pain management in non-traumatic emergency general surgery: WSES-GAIS-SIAARTI-AAST guidelines

Postoperative pain management in non-traumatic emergency general surgery: WSES-GAIS-SIAARTI-AAST guidelines

Pentazocine

Efficacy of Oral Gabapentin and Acetaminophen for Postoperative Analgesia in Anorectal Surgery: A Fuzzy Logic Evaluation

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