Effectiveness of proprioceptive neuromuscular facilitation therapy and strength training among post-menopausal women with thumb carpometacarpal osteoarthritis. A randomized trial

Campos-Villegas, Cristina; Pérez‐Alenda, Sofía; Carrasco, Juan J.; Camacho, Celedonia Igual; Tomás-Miguel, José Manuel; Cortés‐Amador, Sara

doi:10.1016/j.jht.2022.07.005

Cited by 5 publications

(6 citation statements)

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“…The most significant underlying mechanism for this phenomenon is considered the activation of descending inhibitory pathways resulting in widespread hypoalgesia even after a single bout of exercise [31,43]. Considering that significant widespread sensitization has been identified in patients with CMCJ OA, exercise-induced hypoalgesia can be a valuable option to improve the treatment outcomes in patients with the condition [19]. Also, exercise-based interventions have been reported to relieve several pathological mechanisms of OA [43].…”

Section: Exercise-based Interventions Have Better Results Than No Tre...mentioning

confidence: 99%

“…Subsequent screening of titles and abstracts resulted in 29 eligible publications for full-text assessment. Fifteen studies did not satisfy the inclusion criteria and fourteen RCTs were finally included [19][20][21][22][23][24][25][26][27][28][29][30][31][32]. The flow chart of the study selection is presented in Figure 1.…”

Section: Studies Selectionmentioning

confidence: 99%

“…Exercise as an intervention was used alone or in combination with a multimodal physiotherapy programme [20][21][22][26][27][28][29][30] and orthotic devices [20,22,23,[25][26][27]32]. Eight trials evaluated the use of exercises against a multimodal therapeutic programme [20][21][22][23]26,27,30,31], another exercise programme [19,24], no treatment [29,32], joint protection alone [25] or corticosteroid injections [28]. Exercise-based therapy programmes were used for between 2 and 12 weeks.…”

Section: Description Of the Studiesmentioning

confidence: 99%

“…Exercise-based therapy programmes were used for between 2 and 12 weeks. Nine of the eligible trials evaluated the use of proprioceptive exercise programmes [19][20][21][22][23][24][25][26][27]. Three of the eligible trials evaluated the use of mobility and strengthening exercises while two trials focused on the use of neurodynamic exercises (Table 1).…”

Section: Description Of the Studiesmentioning

confidence: 99%

“…Figure 4. Forest plot for the effectiveness of the use of proprioceptive training compared with standard treatment in wrist disability in patients with thumb carpometacarpal osteoarthritis[19,20,[22][23][24]26,27].…”

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confidence: 99%

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Exercise-Based Interventions Are Effective in the Management of Patients with Thumb Carpometacarpal Osteoarthritis: A Systematic Review and Meta-Analysis of Randomised Controlled Trials

Karanasios,

Mertyri,

Karydis

et al. 2024

Healthcare

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Exercise-based interventions are a common management strategy in patients with thumb carpometacarpal joint osteoarthritis (CMCJ OA); however, their exact effect on or the use of an optimal training programme for reducing pain and disability remains unclear. Our purpose was to evaluate the effectiveness of exercise-based interventions compared with other conservative interventions in patients with CMCJ OA. We performed a systematic review and meta-analysis based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Fourteen randomised clinical trials with 1280 patients were finally included. Exercise-based interventions present statistically and clinically better outcomes in reducing pain intensity (mean difference [MD]: −21.91; 95% confidence interval [CI]: −36.59, −7.24; p = 0.003) and wrist disability (MD: −8.1, 95% CI: −4.6, −11.5; p = 0.02) compared with no treatment at short-term follow-up. Proprioceptive exercises have statistically and clinically better outcomes compared with standard care only in pain intensity at very short-term (standardised mean difference [SMD]: −0.76; 95% CI: −1.30, −0.21; p = 0.007) and short-term (SMD: −0.93; 95% CI: −1.86, −0.01; p = 0.049) follow-up and statistically better results in wrist disability at very short-term (SMD: −0.94; 95% CI: −1.68, −0.21; p = 0.01) follow-up. No differences were found between the comparators at mid- and long-term follow-up. Low to moderate certainty of evidence suggests that exercise-based interventions can provide clinically better outcomes compared with no treatment in patients with thumb CMCJ OA, at least in the short term.

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