Effectiveness of Physical Activity and Exercise on Ambulatory Blood Pressure in Adults with Resistant Hypertension: A Systematic Review and Meta-Analysis

Dassanayake, Suranga; Sole, Gisela; Wilkins, Gerard T.; Gray, Emily; Skinner, Margot

doi:10.1007/s40292-022-00517-6

Cited by 9 publications

(7 citation statements)

References 43 publications

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“…With regard to blood pressure, a recent meta-analysis of data from 1207 hypertensive patients showed a significant reduction in systolic (−10 mmHg) and diastolic (−5.5 mmHg) blood pressure in subjects following aerobic training programs [ 23 ], with High-Intensity Interval Training (HIIT) also showing a significant reduction in older patients [ 24 ]; in addition, it has recently been shown that physical activity and exercise added to the usual care may further reduce BP in patients with resistant hypertension [ 25 ]; similar results have been observed in T2DM patients [ 26 ]. Similarly, strength training, by resulting in skeletal muscle hypertrophy, can lead to increased tissue responsiveness to insulin in terms of glucose storage and utilization.…”

Section: Cardiovascular Benefits Of Exercisementioning

confidence: 99%

Effects of Exercise on Heart Failure with Preserved Ejection Fraction: An Updated Review of Literature

Crisci

Luca

D’Assante

et al. 2022

JCDD

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Heart failure with preserved ejection fraction (HFpEF) represents the most common HF phenotype of patients aged > 65 years, with an incidence and a prevalence that are constantly growing. The HFpEF cardinal symptom is exercise intolerance (EI), defined as the impaired ability to perform physical activity and to reach the predicted age-related level of exercise duration in the absence of symptoms—such as fatigue or dyspnea—and is associated with a poor quality of life, a higher number of hospitalizations, and poor outcomes. The evidence of the protective effect between exercise and adverse cardiovascular outcomes is numerous and long-established. Regular exercise is known to reduce cardiovascular events and overall mortality both in apparently healthy individuals and in patients with established cardiovascular disease, representing a cornerstone in the prevention and treatment of many cardio-metabolic conditions. Several studies have investigated the role of exercise in HFpEF patients. The present review aims to dwell upon the effects of exercise on HFpEF. For this purpose, the relevant data from a literature search (PubMed, EMBASE, and Medline) were reviewed. The analysis of these studies underlines the fact that exercise training programs improve the cardiorespiratory performance of HFpEF patients in terms of the increase in peak oxygen uptake, the 6 min walk test distance, and the ventilatory threshold; on the other hand, diastolic or systolic functions are generally unchanged or only partially modified by exercise, suggesting that multiple mechanisms contribute to the improvement of exercise tolerance in HFpEF patients. In conclusion, considering that exercise training programs are able to improve the cardiorespiratory performance of HFpEF patients, the prescription of exercise training programs should be encouraged in stable HFpEF patients, and further research is needed to better elucidate the pathophysiological mechanisms underpinning the beneficial effects described.

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Section: Cardiovascular Benefits Of Exercisementioning

confidence: 99%

Effects of Exercise on Heart Failure with Preserved Ejection Fraction: An Updated Review of Literature

Crisci

Luca

D’Assante

et al. 2022

JCDD

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“…Several potential mechanisms may explain the association between aerobic activity and mortality. Aerobic physical activity is associated with lower blood pressure [ 30 , 31 ], reduced inflammation [ 32 – 34 ], insulin sensitivity [ 35 , 36 ], and improved lipid profile [ 34 , 37 ] and endothelial function [ 38 , 39 ], leading to lower risks of atherosclerosis and thrombosis. Aerobic physical activity is also associated with lower body fat [ 2 , 3 ], while excess body fat is an important risk factor for cardiovascular disease [ 40 , 41 ] and certain cancer sites [ 42 , 43 ].…”

Section: Discussionmentioning

confidence: 99%

Aerobic, muscle-strengthening, and flexibility physical activity and risks of all-cause and cause-specific mortality: a population-based prospective cohort of Korean adults

et al. 2023

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Background Studies have shown that aerobic and muscle-strengthening physical activities reduce mortality risk. However, little is known about the joint associations of the two activity types and whether other type of physical activity, such as flexibility activity, can provide similar mortality risk reduction. Objectives We examined the independent associations of aerobic, muscle-strengthening, and flexibility physical activities with all-cause and cause-specific mortality in a population-based prospective cohort of Korean men and women. We also examined the joint associations of aerobic and muscle-strengthening activities, the two physical activity types that are recommended by the current World Health Organization physical activity guidelines. Design This analysis included 34,379 Korea National Health and Nutrition Examination Survey 2007–2013 participants (aged 20–79 years) with mortality data linkage through December 31, 2019. Engagement in walking, aerobic, muscle-strengthening, and flexibility physical activities was self-reported at baseline. Cox proportional hazards model was performed to estimate hazard ratios (HRs) and 95% confidence intervals (CIs), adjusting for potential confounders. Results Flexibility physical activity (≥ 5 vs. 0 d/wk) was inversely associated with all-cause (HR [95% CI] = 0.80 [0.70–0.92]; P-trend < 0.001) and cardiovascular mortality (0.75 [0.55–1.03], P-trend = 0.02). Moderate- to vigorous-intensity aerobic physical activity (≥ 50.0 vs. 0 MET-h/wk) was also associated with lower all-cause (HR [95% CI] = 0.82 [0.70–0.95]; P-trend < 0.001) and cardiovascular mortality (0.55 [0.37–0.80]; P-trend < 0.001). Similar inverse associations were observed with total aerobic physical activity, including walking. Muscle-strengthening activity (≥ 5 vs. 0 d/wk) was inversely associated with all-cause mortality (HR [95% CI] = 0.83 [0.68–1.02]; P-trend = 0.01) but was not associated with cancer or cardiovascular mortality. Compared to participants meeting the highest guidelines for both moderate- to vigorous-intensity aerobic and muscle-strengthening physical activities, those not meeting in any guideline were associated with higher all-cause (1.34 [1.09–1.64]) and cardiovascular mortality (1.68 [1.00-2.82]). Conclusions Our data suggest that aerobic, muscle-strengthening, and flexibility activities are associated with lower risk of mortality.

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“…зменшує ризик інсульту на 27%, ІХС на 17%, ХСН на 28% і смертності від усіх причин на 13% [1, 5, 23,25] . У систематичному огляді, опублікованому в 2022 році, було виявлено, що фізичні вправи виявляються ефективними для зниження АТ для пацієнтів з резистентною до лікування АГ [26] . Крім того, регулярна аеробна фізична активність зменшує безсоння і покращує тривалість та якість нічного сну, що сприяє поліпшенню метаболічних порушень [9, 12-25] .…”

Section: сприятливий вплив фізичної активності на артеріальну гіперте...unclassified

“…У пацієнтів з АГ регулярна фізична активність пов'язана з регресом або профілактикою гіпертрофії лівого шлуночка (ГЛШ) . Цей позитивний вплив на ремоделювання гіпертензивного серця не залежить від маси тіла та змін АТ під час фізичного навантаження [26] . Результати досліджень підтвердили, що оптимізація способу життя може знизити АТ у тій же мірі, що і деякі антигіпертензивні препарати .…”

Section: сприятливий вплив фізичної активності на артеріальну гіперте...unclassified

“…За умов дотримання гіпокалорійної дієти і регулярної фізичної активності на оптимальному рівні, у пацієнтів з порушенням толерантності до глюкози ризик розвитку ЦД-2 знижується на 40%-60% [22,26,27] . У пацієнтів з ЦД-2 зміна малорухливого способу життя на оптимальну фізичну активність сут-тєво знижує рівень HbA1c незалежно від змін маси тіла [31] .…”

Section: вплив фізичної активності на ір та її прогресування до цд-2 ...unclassified

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Insulin resistance and cardiovascular diseases: focus on common in pathogenesis and treatment.

Zhuravlyova,

Rohachova,

Sokolnikova

et al. 2023

Shidnoevr. z. vnutr. simejnoi med.

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The prevalence of cardiovascular disease and type 2 diabetes has increased dramatically worldwide over the past 30 years. These diseases have become a worldwide epidemic and the main cause of disability and premature death. The reasons for these negative trends are the wide distribution of improper nutrition, sedentary lifestyle, smoking, lack of sleep, which lead to the development of insulin resistance. Insulin resistance underlies the development of multiple metabolic disorders: hyperinsulinemia, hyperglycemia, proatherogenic dyslipidemia, and inflammation, which lead to cardiovascular disease and type 2 diabetes. With this in mind, scientists and medical professionals should focus on the development and implementation of effective methods for the prevention and treatment of insulin resistance. An important tasks are the implementation of a healthy lifestyle, namely proper nutrition and regular physical activity, the use of pharmacological drugs that improve cardiovascular risk factors. However, there remains a need for further research and improvement of these treatment methods, as well as the development of new methods of prevention and treatment of cardiovascular diseases and type 2 diabetes.

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Effectiveness of Physical Activity and Exercise on Ambulatory Blood Pressure in Adults with Resistant Hypertension: A Systematic Review and Meta-Analysis

Cited by 9 publications

References 43 publications

Effects of Exercise on Heart Failure with Preserved Ejection Fraction: An Updated Review of Literature

Effects of Exercise on Heart Failure with Preserved Ejection Fraction: An Updated Review of Literature

Aerobic, muscle-strengthening, and flexibility physical activity and risks of all-cause and cause-specific mortality: a population-based prospective cohort of Korean adults

Insulin resistance and cardiovascular diseases: focus on common in pathogenesis and treatment.

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