Effectiveness of Periurethral Injection on Stress Urinary Incontinence

Abstract

A AB BS S T TR RA AC CT T O Ob b j je ec c t ti i v ve e: : To determine one-year subjective and objective evaluation results of periurethral injection (PUI) applied to women suffering from stress urinary incontinence (SUI). M Ma a t te e r ri i a al l a an nd d M Me et t h ho od ds s: Twenty five patients with complaints of SUI have participated in our study. Preoperative and postoperative results of urinalysis, stress and Q-tip tests, post voiding residual volumes (RV) and survey of incontinence quality of life (I-QOL) criteria were recorded. Later on, Urodex ® (Cross-linked hyaluronic acid, detxranomere) was injected to them. The cases were monitored at regular intervals for a mean of 14 ± 5.84 months. R Re es su ul lt ts s: : Eighteen (72%) out of all cases were encountered during menopausal period. Eight of the patients had previous gynecologic operations. Mean age was 53.97 ± 13.01 years. Mean application period of PUI was 6.95 ± 1.46 minutes. Differences between the preoperative and postoperative results of RV and I-QOL were not statistically significant. From subjective success point of view; 17 (68%) of the patients claimed no change on their incontinence problem, two (8%) of the patients claimed that their conditions were slightly improved, and six (24%) of the patients claimed that their conditions significantly improved. When objective success is considered, there was success in seven (28%) patients, and failure in 18 (72%) patients. C Co on nc cl lu us si io on n: : PUI is a minimally invasive treatment method used in all types of SUI. PUI treatment might be preferred for the old, obese patients with additional health problems, having incontinence dependent on hypermobility at which the open surgery incurs a great risk. However, as the new techniques are not readily available, a periurethral injection technique may still be a valid choice in patients who have poor surgical risks, and to whom the low success rate has been adequately explained.K Ke ey y W Wo or rd ds s: : Urinary incontinence, stress; urinary bladder neck obstruction Ö ÖZ ZE ET T A Am ma aç ç: : Stres üriner inkontinansı (SUI) kadınlarda uygulanan periüretral enjeksiyonun (PUI) sonuçlarının subjektif ve objektif olarak değerlendirilmesi. G Ge e r re eç ç v ve e Y Yö ön n t te em m l le er r: SUI nedeniyle başvuran 25 hasta çalışmaya alındı. Preoperatif ve postoperatif olarak idrar tetkiki, stres ve Q-tip testleri, post-voiding rezidü volümleri (RV) ve inkontinans yaşam kalitesi anket (I-QOL) ölçümleri incelendi. Daha sonra bu hastalarda Urodex ® (Cross-linked hyaluronic acid, dekstranomere) enjeksiyonu uygulandı. Hastalar ortalama 14 ± 5.84 ay süresince düzenli aralıklarla izlendi. B Bu ul l g gu u --l la ar r: Tüm olguların 18'i (%72) menopozal dönemde çalışmaya alınmıştı. Hastaların sekizi daha önceden jinekolojik operasyon geçirmişti. Yaş ortalaması 53.97 ± 13.01 idi. Ortalama PUI uygulama süresi 6.95 ± 1.46 dk. idi. Preoperatif ve postoperatif dönemdeki RV ve I-QOL arasında anlamlı farklılık gözlenmedi. Subjektif yarar açısından b...