Effectiveness of intranasal steroids on rhinitis symptoms, sleep quality, and quality of life in patients with perennial allergic rhinitis

Abdelhafeez, Marwa

doi:10.1007/s00405-021-06818-1

Cited by 9 publications

(8 citation statements)

References 29 publications

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“…Intranasal corticosteroids and oral antihistamines can be used alone or in combination for the treatment of allergic rhinitis. 1,2,12 All 3 of the present study’s treatment groups exhibited significant improvement after treatment; however; group 1 (intranasal steroids alone) had the least benefit from treatment, which is in contrast to some studies that recommend intranasal corticosteroids over oral antihistamines. 13 -15 In group 1 the pre-treatment to post-treatment decrease in the INS score and symptom severity scores was less than in groups 2 and 3, and the difference was significant.…”

Section: Discussioncontrasting

confidence: 95%

Intranasal Schirmer Test in Allergic Rhinitis: Relationship to Symptom Scores and Role in Determining Response to Treatment

Çelebi

Server

Kırgezen

et al. 2023

Ann Otol Rhinol Laryngol

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Objectives: The Intranasal Schirmer test (INS) is an easy to administer test that can yield objective measurement of the quantity of nasal secretion and has been studied in patients with various nasal and systemic pathologies; however, the role of INS in patients with allergic rhinitis remains unclear. Our aim was to determine the relationship between various allergic symptoms and the Intranasal Schirmer Test (INS) score and to evaluate the utility of INS in determining treatment effect in patients with allergic rhinitis. Methods: This prospective study included patients with allergic rhinitis who were randomly divided into 3 treatment groups (nasal steroid only, oral antihistamine only, nasal steroid and oral antihistamine). For all patients, Total Nasal Symptom Score (TNSS) was used to measure symptom severity and INS was administered before and after treatment. Pre-treatment and post treatment TNSS and INS scores were compared between different treatment groups and within each group. Results: The study included 120 patients, with 40 patients in each group. There were significant differences both in pre-treatment and post-treatment symptom severity score with changes of INS scores between treatment groups ( P < .001 and P = .002, respectively). There was a significant difference between pre-treatment and post-treatment symptom severity scores and the INS score in each treatment group ( P < .001). There was also a significant positive correlation between INS score and TNSS ( r = .591 and P < .001). Conclusion: The Intranasal Schirmer Test can be used as an objective tool for patients with allergic rhinitis as an adjunct to subjective patient symptom reports and can also be used to determine the response to treatment.

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Section: Discussioncontrasting

confidence: 95%

Intranasal Schirmer Test in Allergic Rhinitis: Relationship to Symptom Scores and Role in Determining Response to Treatment

Çelebi

Server

Kırgezen

et al. 2023

Ann Otol Rhinol Laryngol

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“…Patients with seasonal and perennial AR complain of disturbed sleep at night, as well as symptoms of awakening in the morning. 1 The earliest chronobiological characterization of AR was by Trousseau in 1865. Since then, many studies have examined the day-night variation and intensity of AR, 2 with several controversial issues remaining under debate.…”

Section: Introductionmentioning

confidence: 99%

Allergic rhinitis and sleep disorders in children – coexistence and reciprocal interactions

D’Elia

Gozal

Bruni

et al. 2022

Jornal de Pediatria

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“…Their results showed that intranasal corticosteroids improved nasal symptoms of sleep quality, somnolence, and daytime fatigue, and had positive impacts on the QoL of the patients. 31 In Phinyo et al's 32 meta-analysis, they reported that 50% or more intranasal corticosteroid doses showed a similar efficacy as regular intranasal corticosteroids in improving QoL and nasal symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…Other effects may also be involved. [25][26][27][28][29][30] Abdelhafeez 31 investigated the effect of intra-nasal corticosteroids on QoL of the patients with perennial allergic rhinitis. Patients used budesonide topical aqueous nasal spray for 8 weeks.…”

Section: Discussionmentioning

confidence: 99%

Effects of Anatolian Propolis and Hypertonic Saline Combination Nasal Spray on Allergic Rhinitis Symptoms: A Prospective, Multicenter Study

Cingi,

Bayar Muluk,

Çukurova

et al. 2024

Ear Nose Throat J

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Objectives: This study aimed to evaluate how Rhinapi nasal spray affects symptoms of allergic rhinitis. Methods: In this prospective, multicenter, observational study, 10,000 patients (comprising 5028 males and 4972 females) exhibiting symptoms of allergic rhinitis (namely, nasal discharge, sneezing, nasal itching, and nasal obstruction) from different centers in different regions of Turkey were enrolled in the study between March 2022 and March 2023. All the patients wanted to participate in the study and were administered Rhinapi one puff to each nostril three times a day, for a period of 3 weeks. Total symptom scores, quality of life (QoL) scores, and otolaryngological examination scores were evaluated before and 3 weeks after treatment. Results: The scores for discharge from the nose, sneezing, nasal pruritus, and blockage of the nose all indicated improvement when compared to pre-medication and post-medication. This difference achieved statistical significance ( P < .001). The mean total symptom score fell following treatment ( P < .001): whilst the score was 11.09 ± 3.41 before administering Rhinapi; after administration, the average score was 6.23 ± 2.41. The mean QoL scores also altered after medication ( P < .001), improving from a mean value of 6.44 ± 1.55 to a mean of 7.31 ± 1.24. Significant improvement was also noted in the scores for conchal color and degree of edema after the treatment had been administered ( P < .001). Conclusion: The study demonstrates that Rhinapi nasal spray decreases total symptom scores, and results in improved QoL and otolaryngological examination scores. Propolis spray may be recommended for patients with allergic rhinitis alongside other treatments.

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Effectiveness of intranasal steroids on rhinitis symptoms, sleep quality, and quality of life in patients with perennial allergic rhinitis

Cited by 9 publications

References 29 publications

Intranasal Schirmer Test in Allergic Rhinitis: Relationship to Symptom Scores and Role in Determining Response to Treatment

Intranasal Schirmer Test in Allergic Rhinitis: Relationship to Symptom Scores and Role in Determining Response to Treatment

Allergic rhinitis and sleep disorders in children – coexistence and reciprocal interactions

Effects of Anatolian Propolis and Hypertonic Saline Combination Nasal Spray on Allergic Rhinitis Symptoms: A Prospective, Multicenter Study

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