Effectiveness of Hospital Pharmacist Interventions for COPD Patients: A Systematic Literature Review and Logic Model

Abstract

Purpose This review aimed to summarize empirical evidence about pharmacist-led interventions for chronic obstructive pulmonary disease (COPD) patients in hospital settings and to identify the components of a logic model (including input, interventions, output, outcome and contextual factors) to inform the development of hospital pharmacist’s role in COPD management. Methods A systematic review of literature retrieved from four English databases (PubMed, Web of Science, Scopus, ScienceDirect) and one Chinese database (CNKI) were conducted to identify eligible studies published from inception to March 2022. Studies concerning pharmacist and COPD were identified to screen for randomized controlled studies that focused on pharmacist interventions for COPD at the hospital setting. Results Twenty-nine studies were included in this review. The components of interventions identified were categorized according to the six service domains in the International Pharmaceutical Federation’s Basel Statements, and mainly concerned prescribing, preparation, administration and monitoring but not procurement and training. Extended interventions were also identified including life guidance, psychological counseling, and respiratory function exercise. The most common outputs reported were improvement in medication adherence, rational drug use, level of knowledge, and inhalation technique. The clinical outcomes (symptomatic control, lung function, rates of hospital readmission, length of hospital stay, and adverse drug adverse reactions), humanistic outcomes (quality of life and patient satisfaction), and economic outcomes (drug costs, hospitalization costs, antibiotic costs, and direct costs) were reported only in some studies. The contextual factors mainly included geographical factors, education level of patients, socio-economic factors, and no-smoking policy. Conclusion The evidence for hospital pharmacists’ interventions in improving COPD patients’ outcome is growing. However, considering the challenges of COPD management, hospital pharmacists should further leverage the advantages of cross-sector and multi-disciplinary collaboration in order to provide more comprehensive support to better address the needs of their patients.

Global research trends and hotspots in pharmaceutical care: a bibliometric analysis and visualisation using CiteSpace and VOSviewer

“…Hospital pharmacists have taken advantage of cross-departmental and multidisciplinary collaboration to educate and manage the disease status of patients,27 use remote medication procedures to monitor and guide patients’ medication,8 and conduct cognitive screening for elderly patients with metabolic diseases to eliminate hidden dangers of medication 29. Different levels of graded pharmaceutical care measures are implemented at different stages of the disease,30 which can identify and intervene in drug-related problems in a timely manner in the treatment of COPD and other diseases 31. In addition, it enables correct understanding of the connotation of pharmacy services, forming good values, encouraging innovative strategies such as personalised pharmaceutical care to improve patient satisfaction and improve prognosis 32–34…”

“…29 Different levels of graded pharmaceutical care measures are implemented at different stages of the disease, 30 which can identify and intervene in drug-related problems in a timely manner in the treatment of COPD and other diseases. 31 In addition, it enables correct understanding of the connotation of pharmacy services, forming good values, encouraging innovative strategies such as personalised pharmaceutical care to improve patient satisfaction and improve prognosis. [32][33][34]…”

Exploring the perception and the needs of pharmaceutical care perceived by family caregivers of pediatric asthma patients in Guangdong Province, China: a cross-sectional survey study

“…The design of the questionnaire was based on a previous literature review on pharmacist intervention for pediatric asthma 20 . The questionnaire consisted of 5 sections, including participant quali cation con rmation (1 question), demographics (9 questions), caregivers' perception of asthma-related knowledge (19 questions), the burden on caregivers due to pediatric asthma (5 questions), and their needs of pharmaceutical care provided by community pharmacists (12 questions).…”

Education on Inhaler Technique by Pharmacists To Improve The Quality of Life of COPD Patients: A Systematic Review and Meta-Analysis

“…10,11 Only one systematic review with a randomized controlled trial study reported that the pharmacist's role in the hospital has contributed to various aspects of COPD management, both inpatient and outpatient. 13 Therefore, this systematic review aimed to evaluate specifically the impact of providing education on the technique of using inhalers by hospital pharmacists in improving the quality of life of inpatient and outpatient COPD patients. The purpose of selecting inpatients and outpatients is to assist patients in enhancing treatment safety, patient outcomes, and drug quality over time and to prevent readmissions in inpatient settings.…”