Effectiveness of Hemcon Dental Dressing Versus Conventional Method of Haemostasis in 40 Patients on Oral Antiplatelet Drugs

Abstract

abstract:Objectives: The purpose of the study was to evaluate the effectiveness of the HemCon Dental Dressing (HDD) in controlling post extraction bleeding and to ascertain its role in healing of extraction wounds, as compared to control. Methods: The 40 participants in the study were all receiving oral antiplatelet therapy (OAT). A total of 80 extractions were conducted without altering the patients' drug therapy. The extraction sites were divided into 2 groups: one group received a HDD, and the control group where the conventional method of pressure pack with sterile gauze under biting pressure (followed by suturing if required) was used to achieve haemostasis. Results: All HemCon treated sites achieved haemostasis sooner (mean = 53 seconds) than the control sites (mean = 918 seconds) which was statistically significant (P <0.001). Postoperative pain in the HDD group (1.74) was also significantly lower than in the control group (5.26) (P <0.001). Approximately 72.5% of HDD-treated sites showed significantly better postoperative healing when compared to the control site (P <0.001). Conclusion: HDD proved to be an excellent haemostatic agent that significantly shortened the bleeding time following dental extraction in patients on OAT. Additionally, HDD offered significantly improved post-operative healing of the extraction socket and less postoperative pain. Keywords

Evaluating Effectiveness of Axiostat Hemostatic Material in achieving Hemostasis and Healing of Extraction Wounds in Patients on Oral Antiplatelet Drugs

“…21,22 Comparing the results of this study with our previous study on HemCon Dental Dressing (HDD), the mean time taken to achieve hemostasis is significantly lower when ADD (73 seconds) or HDD (53 seconds) was used compared with conventional method. 4 Increase in the time to achieve hemostasis using ADD is attributed to the fact that the patients with INR up to 3.5 were included in this study in contrast to our previous study on Hemcon dressing where INR limit was 3. On comparing the results of postoperative healing and pain between ADD and Hemcon dressing, both showed similar potential of superior healing and minimal postextraction pain and complications.…”

“…On comparing the results of this study with our previous study on HDD, Axiostat Dental Dressing is found to be as effective and at par in achieving hemostasis in patients on oral antiplatelet therapy. 4 …”

“…Despite the numerous benefits of antiplatelet drugs they are not without risk, i.e., tendency to bleed excessively. 4,5 According to Nichols and Bowie, 6 frequency of patients on antiplatelet therapy seeking dental treatment is increasing day by day worldwide and with the availability of medical facilities it is going to increase further. The use of international normalized ratio (INR) is the gold standard for monitoring patients on antiplatelet therapy, recommended by the American Heart Association and the British Society for Hematology.…”

The effectiveness of a new method using an extra-alveolar hemostatic agent after dental extractions in older patients on oral anticoagulation treatment: an intrapatient study

“…The overall evaluation of all the above-mentioned parameters for each site allowed definition of the type of healing, as better, worse, or equal compared with the control site (Table I). 21 Any postoperative complications were noted in the clinical record.…”

“…7,[15][16][17][18][19] A new adhesive agent, HemCon Dental Dressing (HDD) (Zimmer Holdings, HemCon Medical Technologies, Inc., Beaverton, OR), has been recently introduced into oral surgery and already used for tooth extractions in patients taking antithrombotic drugs. 20,21 It derives from the agent used by the U.S. forces during the wars in Iraq and Afghanistan, which is based on chitosan, a natural biocompatible polysaccharide extracted from the shell of crustaceans. It has proven ability to quickly seal the wound, stabilizing the clot and protecting the mucosa during the healing period, and has an efficient antimicrobial activity against many bacterial species.…”