Effectiveness of Electroacupuncture and Electroconvulsive Therapy as Additional Treatment in Hospitalized Patients With Schizophrenia: A Retrospective Controlled Study

Jia, Jie; Sakata, Jun; Liu, Feihu; Wong, Hai Ming; Yang, Xinjing; Wu, Q.; Zhang, Hui; Wang, Huaning; Tan, Qihua; Zhang, Zhang-Jin

doi:10.3389/fpsyg.2019.02306

Cited by 4 publications

(15 citation statements)

References 43 publications

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“…Patients receiving electroacupuncture along with electroconvulsive therapies were shown to have fewer schizophrenic symptoms than controls. In addition, patients receiving electroacupuncture showed reduced weight as well as reduction in headaches, insomnia, dry mouth, and electrocardiographic abnormalities (Jia et al, 2019).…”

Section: Non-western and Novel Treatments For Schizophreniamentioning

confidence: 99%

Schizophrenia: Epidemiology, Causes, Neurobiology, Pathophysiology, and Treatment

Volkan¹

2020

jhms

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Schizophrenia is a severe mental illness that has devastating consequences for those who suffer from the disorder. The epidemiology of schizophrenia indicates that it occurs relatively often, in many different contexts, and in conjunction with other disorders, decreasing quality of life and causing premature death. There has been an enormous amount of research into the causes of schizophrenia and there is now have a much better understanding of the genetic, environmental, and psychological factors that contribute to the disease. While there are numerous ways to understand and conceptualize schizophrenia, a unified picture of the neurobiology, changes in brain structure, cognitive and social-cognitive impairments related to the disorder has yet to emerge. Convulsive therapies and psychosurgery were used unsuccessfully, indiscriminately and without scientific validation in the past to treat schizophrenia. Medical advances including advanced imaging technology have now provided the ability to perform specifically focused neuromodulation and psychosurgery in severe and treatment resistant cases of schizophrenia. While still at a preliminary stage, these approaches have the potential to yield effective treatments in the future. For the last 70 years antipsychotic medication has become the prevailing treatment for schizophrenia. However, many people suffering from the disorder have trouble with side-effects and adhering to a regimen of antipsychotic medication. Newer pharmacological agents are being developed and include not only novel antipsychotic drugs, but anti-inflammatory and immunomodulating agents as well. These new agents, used either alone or in combination, have the potential to improve outcomes for people suffering from schizophrenia. Nevertheless, conclusively better pharmacotherapies will likely not arise until there is better understanding of the pathophysiology underlying schizophrenia. After the development of antipsychotic medication, psychotherapeutic methods for treating schizophrenia fell out of favor, but there is currently some reversal of this trend. The use of newer psychotherapies and modified forms of older therapeutic treatments are not only targeting the symptoms of schizophrenia but are also now focusing on recovery from the disorder. These newer approaches as well as efforts at preventing schizophrenia show promise in reducing the suffering caused by this disease.

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Section: Non-western and Novel Treatments For Schizophreniamentioning

confidence: 99%

Schizophrenia: Epidemiology, Causes, Neurobiology, Pathophysiology, and Treatment

Volkan¹

2020

jhms

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“…From the 35 included publications investigating the effect of ECT on schizophrenia, 16 were prospective interventional studies (Chanpattana & Chakrabhand, 2001a;Chanpattana & Kramer, 2003;Chanpattana & Sackeim, 2010;Ipekcioglu et al, 2018;Jia et al, 2019;Kho et al, 2004;Li et al, 2016;Masoudzadeh et al, 2007;Pawełczyk et al, 2014aPawełczyk et al, , 2014bPetrides et al, 2015;Tang & Ungvari, 2001Zhang et al, 2012), two naturalistic observation studies (Kim et al, 2018;Usta Saglam et al, (Bansod et al, 2018), one retrospective controlled study (Jia et al, 2019) and one retrospective chart review (Xiang et al, 2015). Six literature reviews (Chanpattana, 2007;Chanpattana & Andrade, 2006;Dokucu, 2015;Hasan et al, 2015b;Lehnhardt et al, 2012;Remington et al, 2016), two systematic reviews (Sinclair et al, 2019;Tharyan & Adams, 2005) and two meta-analyses (Ahmed et al, 2017;Zheng et al, 2016), giving an overview of some aspects of the effect of ECT on schizophrenia, were also included in this review.…”

Section: Study Characteristics and Designmentioning

confidence: 99%

“…Five of these prospective interventional studies also used a controlled study design (Li et al, 2016;Petrides et al, 2015;Tang & Ungvari, 2002;Zhang et al, 2012), but these studies were limited by control groups with patients who refused ECT and instead only received pharmacotherapy. The only retrospective study during the period from 2000 to 2021 was a controlled study comparing ECT to electroacupuncture and a control group (Jia et al, 2019).…”

Section: Study Characteristics and Designmentioning

confidence: 99%

“…Exclusion criteria were less heterogeneous between the studies, with eleven of them excluding patients with a severe medical disorder in which ECT is contra-indicated or current use of alcohol or substance abuse (Chanpattana & Chakrabhand, 2001a;Chanpattana & Kramer, 2003;Chanpattana & Sackeim, 2010;Davarinejad et al, 2019;Ipekcioglu et al, 2018;Jia et al, 2019;Kim et al, 2018;Pawełczyk et al, 2014aPawełczyk et al, , 2014bPetrides et al, 2015;Tang & Ungvari, 2002Xiang et al, 2015;Zhang et al, 2012). The ages of the patients in the included publications ranged from 15 to 75 years.…”

Section: Sample Characteristicsmentioning

confidence: 99%

“…In 16 of the 21 studies, the patients received ECT three times a week in the acute phase (Chanpattana & Chakrabhand, 2001a;Chanpattana & Kramer, 2003;Chanpattana & Sackeim, 2010;Ipekcioglu et al, 2018;Jia et al, 2019;Kho et al, 2004; Records identified: database searching (n=86); reference lists of included studies (n=2); expert recommendations (n=3) Record abstracts and summaries screened after the removal of duplicates (n=56)…”

Section: Treatment Plansmentioning

confidence: 99%

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Electroconvulsive therapy for negative symptoms in schizophrenia: a literature review from 2000 to 2021

et al. 2021

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Negative symptoms in schizophrenia remain a clinical challenge with small effect sizes and evidence for pharmacological or psychotherapeutic treatment approaches. Studies suggest that electroconvulsive therapy (ECT) holds some promise as a treatment option of often persistent negative symptoms with clinically meaningful effects. This review summarizes the existing evidence on the efficacy of ECT on negative symptoms in patients with schizophrenia. Thirty-five publications were included in this literature review comprising 21 studies, two meta-analyses, eight reviews and four case reports. Conclusions should be interpreted cautiously, given the small number and methodological shortcomings of the included publications with a variation of study designs and missing standardized protocols. Implications for future research and practice are critically discussed. Recommendations are given to provide more evidence that will meet the clinical challenge of reducing the negative symptoms in schizophrenia. Study designs that focus explicitly on negative symptoms and assess patients over longer follow up periods could be helpful. Future research should include control groups, and possibly establish international multicentered studies to get a sufficient study population. Findings suggest that patients with schizophrenia resistant to pharmacological treatment might benefit from ECT. A risk and benefit assessment speaks in favour of the ECT treatment. Future practice of ECT should include a combination treatment with antipsychotics. Whereas the use of anaesthetics and electrode placement does not seem to play a role, the recommendation regarding frequency of ECT treatments is currently three times a week, For the assessment of negative symptoms the assessment tool should be chosen carefully.

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Akupunktur in der Psychiatrie – Chancen und Grenzen

Musil¹,

Hofer²,

Colling³

2021

Zeitschrift für Komplementärmedizin

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SummaryAkupunktur wird in zunehmendem Umfang an deutschen psychiatrischen Kliniken angeboten. Die Evidenz in der publizierten Literatur hat über die letzten Jahre deutlich zugenommen. Die Qualität der Studien muss sich allerdings weiterhin verbessern, um zu klaren Ergebnissen und Empfehlungen in Metaanalysen zu kommen. Insbesondere bei depressiven Erkrankungen und Traumafolgestörungen könnte Akupunktur durch seine Nebenwirkungsarmut in Zukunft einen größeren Stellenwert gewinnen. Akupunktur lässt sich in unterschiedliche Behandlungsstrategien relativ einfach integrieren. Eine große Hürde stellt allerdings die geringe Verbreitung einer ausreichenden Ausbildung bei Behandlern in psychiatrischen und psychosomatischen Kliniken dar.

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Effectiveness of Electroacupuncture and Electroconvulsive Therapy as Additional Treatment in Hospitalized Patients With Schizophrenia: A Retrospective Controlled Study

Cited by 4 publications

References 43 publications

Schizophrenia: Epidemiology, Causes, Neurobiology, Pathophysiology, and Treatment

Schizophrenia: Epidemiology, Causes, Neurobiology, Pathophysiology, and Treatment

Electroconvulsive therapy for negative symptoms in schizophrenia: a literature review from 2000 to 2021

Akupunktur in der Psychiatrie – Chancen und Grenzen

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