Effectiveness of Duloxetine on Oxaliplatin-induced Allodynia and Hyperalgesia in Rats
Monica A. Wagner,
Ellen M. Lavoie Smith,
Naji Ayyash
et al.
Abstract:Development of painful oxaliplatin-induced peripheral neuropathy (OIPN) is a major problem in people who receive oxaliplatin as part of cancer treatment. The pain experienced by those with OIPN can be seriously debilitating and lead to discontinuation of an otherwise successful treatment. Duloxetine is currently the only recommended treatment for established painful OIPN recommended by the American Society of Clinical Oncology, but its preventative ability is still not clear. This study examined the ability of… Show more
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