Effectiveness of current therapy of bacterial vaginosis

Andreeva, P; Omar, Hatim A.

doi:10.1515/ijamh.2002.14.2.145

Cited by 10 publications

(5 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, it is recommended to take dietary suplements such are probiotics. Probiotics are very important factors in various infections prevention 17,18 . Due to hormone level changes before menstrual bleeding and during pregnancy, the growth of yeast can be enhanced due to vaginal pH changes.…”

Section: Discussionmentioning

confidence: 99%

The influence of probiotics on the cervical malignancy diagnostics quality

et al. 2011

View full text Add to dashboard Cite

The application of probiotic strains Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 concomitantly with specific anti-infective agents provides more reliable cytological diagnostics, reduces the number of false positive and false negative findings on cervical malignancy and normalizes vaginal microflora in higher percentage of patients with vaginal infections comapred with therapy including antiinfective agents only.

show abstract

Section: Discussionmentioning

confidence: 99%

The influence of probiotics on the cervical malignancy diagnostics quality

et al. 2011

View full text Add to dashboard Cite

show abstract

“…The vaginal clindamycin cream appears less efficacious than the metronidazole regimens” (91), statements that do not agree with our review of published data and recently published studies with cure rates below 50% (39, 45). The treatment recommended by the WHO – use of single‐dose metronidazole – showed in an open study that 39% of the 31 women who came back for a follow‐up visit already after 1–3 weeks needed new treatment for BV (92). The question arises whether the true cure rate is even lower than this.…”

Section: Discussionmentioning

confidence: 99%

Bacterial vaginosis – a disturbed bacterial flora and treatment enigma

Larsson

Forsum

2005

APMIS

View full text Add to dashboard Cite

The syndrome bacterial vaginosis (BV) is characterized by a disturbed vaginal microflora in which the normally occurring lactobacilli yield quantitatively to an overgrowth of mainly anaerobic bacteria. As BV is a possible cause of obstetrics complications and gynaecological disease--as well as a nuisance to the affected women--there is a strong impetus to find a cure. In BV treatment studies, the diagnosis criteria for diagnosis of BV vary considerably and different methods are used for cure evaluation. The design of study protocols varies and there is no consensus respecting a suitable time for follow-up visits. For the purpose of this review, available data were recalculated for 4-week post treatment cure rates. For oral metronidazole the 4-week cure rate was found not to exceed 60-70%. Treatment regimens with topical clindamycin or topical metronidazole have the same cure rates. It can thus be said that no sound scientific basis exists for recommending any particular treatment. There is no evidence of beneficial effects on BV engendered by partner treatment, or by addition of probiotics or buffered gel. Long-term follow-up (longer than 4 weeks) shows a relapse rate of 70%. With a primary cure rate of 60-70%, and a similar relapse rate documented in the reviewed literature, clinicians simply do not have adequate data for determining treatment or designing clinical studies. This is unfortunate since--apart from the obvious patient benefits--clinical studies can often serve as a guide for more basic studies in the quest for underlying disease mechanisms. In the case of BV there is still a need for continued basic studies on the vaginal flora, local immunity to the flora and host-parasite interactions as an aid when designing informative clinical studies.

show abstract

“…Although actual incidence figures are impossible to obtain, bacterial vaginosis is regarded as the most common cause of vaginal symptoms. This infection is commonly found in women aged 17-30 years of age, 6 but is also prevalent in older women. Bacterial vaginosis may occur in women without any symptomatology, but it is generally associated with a homogenous white vaginal discharge.…”

Section: Bacterial Vaginosismentioning

confidence: 99%

Urogenital infections in women: can probiotics help?

Reid

Bruce

2003

Postgraduate Medical Journal

122

View full text Add to dashboard Cite

Urogenital infections not caused by sexual transmission, namely yeast vaginitis, bacterial vaginosis, and urinary tract infection remain a major medical problem in terms of the number of women afflicted each year. Although antimicrobial therapy is generally effective at eradicating these infections, there is still a high incidence of recurrence. The patient’s quality of life is affected and many women become frustrated by the cycle of repeated antimicrobial agents whose effectiveness is diminishing due to increasing development of microbial resistance. There is good clinical evidence to show that the intestinal and urogenital microbial flora have a central role in maintaining both the health and wellbeing of humans. Furthermore, the use of “good bacteria” to replace or augment bacterial populations is gradually achieving scientific acceptance. This application is termed probiotics: “live micro-organisms which when administered in adequate amounts confer a health benefit on the host”. The role of the intestinal, vaginal, and urethral flora and probiotics in urogenital health will be the focus of this review.

show abstract

Effectiveness of current therapy of bacterial vaginosis

Cited by 10 publications

References 10 publications

The influence of probiotics on the cervical malignancy diagnostics quality

The influence of probiotics on the cervical malignancy diagnostics quality

Bacterial vaginosis – a disturbed bacterial flora and treatment enigma

Urogenital infections in women: can probiotics help?

Contact Info

Product

Resources

About