Effectiveness of combined botulinum toxin and fissurectomy on chronic anal fissures – a systematic review
Rakesh Quinn,
Giuleta Jamsari,
Gary KK Low
et al.
Abstract:BackgroundAnal fissures are a debilitating benign condition, thought to be due to the hypertonicity of the internal anal sphincter resulting in localized ischaemia inhibiting healing. There are several surgical and non‐surgical treatment options for chronic anal fissures. Clinical practice surveys report a trend toward sphincter‐sparing options, reserving the more successful treatment of lateral sphincterotomy, with an incontinence rate up to 10%, for refractory fissures.MethodsA search of MEDLINE, Cochrane Da… Show more
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