Effectiveness of Cognitive-behavioral Therapy and Mental Imagery Exercises on Health-related Quality of Life of Patients With Leukemia and Lymphoma

Abstract

Background: Patients with cancer experience high levels of psychological distress, which leads to depressive symptoms, severe anxiety, and decreased quality of life. The present study aimed to determine the effectiveness of cognitive-behavioral therapy (CBT) and mental imagery exercises (MIE) on health-related quality of life (HRQOL) of patients with leukemia and lymphoma in Babol province- Iran. Methods: It was a field trial with a pretest-posttest design and a control group. The statistical population consisted of all male and female patients with leukemia and lymphoma referring to the hematology department of Ayatollah Rouhani Hospital of Babol province in 2019. A total of 45 patients were recruited based on the inclusion criteria and were randomly assigned into two experimental groups and one control group (15 per group). The first experimental group received eight 90-minute sessions of individual CBT and the second experimental group received ten 90-minute sessions of MIE. The control group received no intervention. Data were collected by the 36-Item Short Form Survey (SF-36) before and also 45 days after the last treatment session and were analyzed using descriptive and inferential statistics, such as mean, standard deviation, and analysis of covariance (ANCOVA) in SPSS software version 23.0. Results: The results indicated that CBT and MIE had a positive significant effect on HRQOL in patients with leukemia and lymphoma (P<0.001). There was no significant difference between the effectiveness of the two therapies. Conclusions: Considering the effectiveness of the CBT and MIE on HRQOL in patients with cancer, they are suggested to be utilized extensively along with medical and clinical interventions in order to improve the HRQOL of cancer patients.