Effectiveness of apixaban in warfarin hepatotoxicity: A case report

Abstract

Background: Apixaban is a direct and competitive inhibitor of factor Xa. It has been shown to be effective and safe to Prevent Stroke in Atrial Fibrillation Patients. This study is a case report of warfarin-induced cholestasis that occurred one week after starting warfarin for deep venous thrombosis, in which the cholestasis improved after the offending drug was stopped but worsened after beginning apixaban.