Effectiveness of a short video-based educational intervention on factors related to clinical trial participation in adolescents and young adults: a pre-test/post-test design

Abstract

BackgroundPoor clinical trial enrollment continues to be pervasive and is especially problematic among young adults and youth, and among minorities. Efforts to address barriers to enrollment have been predominantly focused on adult diseased populations. Because older adults may already have established attitudes, it is imperative to identify strategies that target adolescents and young adults. The purpose of this study was to test the effectiveness of an educational video on factors related to clinical trial participation among a healthy adolescent and young adult population.MethodsParticipants completed a 49-item pre-test, viewed a 10-min video, and completed a 45-item post-test to assess changes in attitudes, knowledge, self-efficacy, receptivity to, and intention to participate (primary outcome) in clinical trials. Descriptive statistics, paired samples t-tests, and Wilcoxon signed-rank tests were conducted.ResultsThe final analyses included 935 participants. The mean age was 20.7 years, with almost 70% aged 18 to 20 years. The majority were female (73%), non-Hispanic (92.2%), white (70%), or African American (20%). Participants indicated a higher intention to participate in a clinical trial (p < 0.0001) and receptivity to hearing more about a clinical trial (p < 0.0001) after seeing the video. Intention to participate (definitely yes and probably yes) increased by an absolute 18% (95% confidence interval 15–22%). There were significant improvements in attitudes, knowledge, and self-efficacy scores for all participants (p < 0.0001).ConclusionsThe results of this study showed strong evidence for the effectiveness of a brief intervention on factors related to participation in clinical trials. This supports the use of a brief intervention, in a traditional educational setting, to impact the immediate attitudes, knowledge, self-efficacy, and intention to participate in clinical trial research among diverse, healthy adolescents and young adults.

A qualitative study of barriers and facilitators to adolescents and young adults’ participation in cancer clinical trials: Oncologist and patient perspectives

“…Our findings are supported by a recent systematic review, which found that health illiteracy and poor communication between health providers and AYA cancer patients are major barriers for CT enrollment 3 . Educational interventions, such as a short video with information about CTs, may increase AYAs willingness to learn about and participate in CTs 38 . Additionally, strategies to increase educational resources can help clinicians to better advise their patients about CTs 3 …”

“…3 Educational interventions, such as a short video with information about CTs, may increase AYAs willingness to learn about and participate in CTs. 38 Additionally, strategies to increase educational resources can help clinicians to better advise their patients about CTs. 3 Other hospital staff such as research nurses and clinical research coordinators are key to provide additional education on CTs for AYAs.…”

Evaluation of Adolescents’ and Young Adults’ Attitudes Toward Participation in Cancer Clinical Trials

“…Short video educational tools have been shown to be effective in increasing receptivity to hearing about and participating in clinical trials in the healthy AYA population. 34 Although there are reports that AYAs perceive their inclusion in clinical trials may lead to improved quality of care 35 or that they participate for altruistic reasons, 10 only limited data suggest that CCT involvement actually leads to reduced quality of life. 36 Ensuring communication of accurate information about trials and that trials for AYAs minimize additional patient burden where allowed can address concerns about trials making "treatment more difficult" and "more trouble than standard care."…”

A Decade of Short Videos for Foreign Language Teaching and Learning: A Review

“…In the same year, short videos, with their characteristics of simplicity, effectiveness, and ease of access and dissemination, had a significant and consistent impact on students' emotions in a nutrition education intervention [11]. Following that, the effectiveness of the intervention's effects on clinical education-related factors was also confirmed [12]. Furthermore, short videos, in addition to direct interventions during teaching, served as feedback interventions to assess students' learning situations [13].…”