Effectiveness of a manual therapy protocol based on articulatory techniques in migraine patients. A randomized controlled trial

Muñoz-Gómez, Elena; Inglés, Marta; Serra-Añó, Pilar; Espí-López, Gemma Victoria

doi:10.1016/j.msksp.2021.102386

Cited by 15 publications

(12 citation statements)

References 51 publications

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“…One recent migraine study of articulatory techniques reported a similar level of clinically signi cant improvement with 52% of the active participants having 'much improved or very much improved' after four weeks with one session per week [112]. A recent calcitonin gene-related peptide (CGRP) study has provided PGIC results for chronic migraine with 64% of the participants "much improved" or "very much improved" when treated with the best performing active Eptinezumab against placebo results of 38% [113].…”

Section: Patient Global Impression Of Change (Pgic)respondersmentioning

confidence: 91%

Effectiveness of Manual Therapy as an Adjunct to Care as Normal in Female Chronic Migraine Patients. A Randomised Controlled Trial

O'Dell¹,

Branney²,

Hunnisett³

2022

Preprint

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Background and purpose The aim of this study was to explore the effectiveness of manual therapy as an adjunctive treatment to usual care in females severely affected with chronic migraine. Methods This was a pragmatic, randomised controlled trial (RCT) in a tertiary headache clinic in the UK. Sixty-four female participants with severe chronic migraine were randomised into two groups: Onabotulinum A (Botox TM) and Botox TM with manual therapy. The Botox TM was given to both groups at the start on a 12-week schedule. The manual therapy was a combination of mobilisation, manipulation and soft tissue release technique and was given 5 times over 12 weeks. The RCT consisted of 3 months intervention with primary outcome measures taken at the end of the study period. The primary outcome was the between-group difference in change scores using the Headache Impact Test (HIT6). Secondary outcomes were Patient Global Impression of Change (PGIC) and responder rates. Results The primary outcome favoured the use of manual therapy as an adjunct to usual tertiary care over usual tertiary care (BotoxTM)alone with a significant difference in between-group HIT6 change scores (p=0.006, d=0.51) The manual therapy group also had significantly more responders based on HIT6 (p=0.006) and PGIC (p= 0.002) outcomes. Conclusions This study has found that manual therapy is an effective adjunct to the usual tertiary care (BotoxTM) of chronic migraine in women. Trial Registration The trial received a favourable opinion from the UK Health Research Authority (IRAS 228901) and is registered at ClinicalTrials.gov.number NCT03395457. Registered 1st March 2018.

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Section: Patient Global Impression Of Change (Pgic)respondersmentioning

confidence: 91%

Effectiveness of Manual Therapy as an Adjunct to Care as Normal in Female Chronic Migraine Patients. A Randomised Controlled Trial

O'Dell¹,

Branney²,

Hunnisett³

2022

Preprint

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“…The intervention protocols performed in this study have been previously described by our research group [ 16 , 20 ]. Briefly, the treatment protocol applied to the STG consisted of the suboccipital inhibition technique, frontal technique, sphenoid technique, fourth ventricle technique and lumbosacral technique.…”

Section: Methodsmentioning

confidence: 99%

“…Regarding articulatory techniques, it has been reported that they may have effects on central nervous system mechanisms responsible for pain control [ 17 ], as well as on the autonomic nervous system, reflected as changes in heart rate variability and skin conductance [ 18 ]. Articulatory techniques have shown beneficial effects on pain, frequency, disability and medication use [ 19 , 20 ]. We also observed that a protocol consisting of articulatory techniques could reduce pain, overall disability and medication intake, and improve the quality of life of migraine patients [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

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Potential Add-On Effects of Manual Therapy Techniques in Migraine Patients: A Randomised Controlled Trial

Muñoz-Gómez

Serra-Añó

Mollà-Casanova

et al. 2022

JCM

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Objective: To ascertain whether the combination of soft tissue and articulatory manual techniques is more effective than either one of these techniques alone for reducing migraine impact; Methods: Seventy-five participants with migraine were randomly divided into three groups (n = 25 per group): (i) soft tissue (STG), (ii) articulatory (AG), and (iii) combined treatment (STAG). Pain, frequency of occurrence, duration, disability and impact, depression and anxiety levels, and perception of change were analysed at baseline, post intervention (T2) and at four-week follow-up (T3); Results: STAG showed a significantly greater reduction in pain versus STG and AG at T2 (p < 0.001; p = 0.014) and at T3 (p < 0.001; p = 0.01). Furthermore, STAG achieved a significantly greater reduction in pain duration versus STG at T2 (p = 0.020) and T3 (p = 0.026) and a greater impression of change versus STG (p = 0.004) and AG (p = 0.037) at T3. Similar effects were observed in all groups for frequency of occurrence, migraine disability, impact, and depression and anxiety levels; Conclusions: A combined manual therapy protocol including soft tissue and articulatory techniques yields larger improvements on pain and perception of change than either technique alone, yet the three therapeutic approaches show similar benefits for reducing pain, disability and impact caused by the migraine, depression or anxiety levels.

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“…This variable was registered as the number of pills per day. The percentage of medication intake reduction was calculated as previously described [43].…”

Section: Assessmentsmentioning

confidence: 99%

Effect of a Craniosacral Therapy Protocol in People with Migraine: A Randomized Controlled Trial

Muñoz-Gómez

Inglés

Aguilar‐Rodríguez

et al. 2022

JCM

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Background: Migraine is a common neurological disorder, and it is the second leading cause of disability worldwide. Manual techniques based on physical therapy have been proposed to improve migraine aspects; however, further research is needed on their effectiveness. The aim of this study was to evaluate the effectiveness of a craniosacral therapy protocol on different features in migraine patients. Methods: Fifty individuals with migraine were randomly divided into two groups (n = 25 per group): (i) craniosacral therapy group (CTG), following a craniosacral therapy protocol, and (ii) sham control group (SCG), with a sham treatment. The analyzed variables were pain, migraine severity and frequency of episodes, functional, emotional, and overall disability, medication intake, and self-reported perceived changes, at baseline, after a 4 week intervention, and at 8 week follow-up. Results: After the intervention, the CTG significantly reduced pain (p = 0.01), frequency of episodes (p = 0.001), functional (p = 0.001) and overall disability (p = 0.02), and medication intake (p = 0.01), as well as led to a significantly higher self-reported perception of change (p = 0.01), when compared to SCG. In addition, the results were maintained at follow-up evaluation in all variables. Conclusions: A protocol based on craniosacral therapy is effective in improving pain, frequency of episodes, functional and overall disability, and medication intake in migraineurs. This protocol may be considered as a therapeutic approach in migraine patients.

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Effectiveness of a manual therapy protocol based on articulatory techniques in migraine patients. A randomized controlled trial

Cited by 15 publications

References 51 publications

Effectiveness of Manual Therapy as an Adjunct to Care as Normal in Female Chronic Migraine Patients. A Randomised Controlled Trial

Effectiveness of Manual Therapy as an Adjunct to Care as Normal in Female Chronic Migraine Patients. A Randomised Controlled Trial

Potential Add-On Effects of Manual Therapy Techniques in Migraine Patients: A Randomised Controlled Trial

Effect of a Craniosacral Therapy Protocol in People with Migraine: A Randomized Controlled Trial

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