Effectiveness of 308‐nm excimer lamp in the treatment of notalgia paresthetica

Fonda‐Pascual, Pablo; Collantes‐Rodríguez, Cristina; Arcos, Leopoldo; Fernández-González, Pablo; Canseco-Martin, Marina; Alcántara-Nicolás, Francisco; Rueda‐Correa, F.; Vidal‐Asensi, S.

doi:10.1111/jdv.16836

Cited by 4 publications

(7 citation statements)

References 10 publications

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“…However, in patients with severe and chronic NP, innervation is decreased in the affected skin parts. Furthermore, the wavelength of the 308‐nm excimer lamp is similar to NB‐UVB 9 . Another advantage of a 308‐nm excimer lamp is that it acts locally on a specific area, unlike NB‐UVB, which needs dose adjustment and imposes unnecessary irradiation on the patient.…”

Section: Discussionmentioning

confidence: 99%

“…Initial reports indicated that botulinum toxin (BTX) could be a viable option, significantly improving itching 8 . Moreover, local and intralesional injection of different substances, narrow‐band ultraviolet B radiation (UVB), excimer lamp, and needling are recognized as alternative procedures that could be promising in treating NP 2,7,9–11 . However, these approaches are currently unapproved for NP due to insufficient evidence regarding their effectiveness and safety.…”

Section: Introductionmentioning

confidence: 99%

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A systematic review of procedural modalities in the treatment of notalgia paresthetica

Nilforoushzadeh,

Ghane,

Heidari

et al. 2024

Skin Research and Technology

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BackgroundNotalgia paresthetica (NP) is a rare condition characterized by localized pain and pruritus of the upper back, associated with a distinct area of hyperpigmentation. Given the lack of standardized treatment and the uncertain efficacy of available options, applying procedural methods is of growing interest in treating NP.AimsWe sought to comprehensively evaluate the role of procedural treatments for NP.MethodsWe systematically searched PubMed/Medline, Ovid Embase, and Web of Science until November 14th, 2023. We also performed a citation search to detect all relevant studies. Original clinical studies published in the English language were included.ResultsOut of 243 articles, sixteen studies have reported various procedural modalities, with or without pharmacological components, in treating NP. Pharmacological procedures, including injections of botulinum toxin, lidocaine, and corticosteroids, led to a level of improvement in case reports and case series. However, botulinum toxin did not show acceptable results in a clinical trial. Moreover, non‐pharmacological procedures were as follows: physical therapy, exercise therapy, kinesiotherapy, acupuncture and dry needling, electrical muscle stimulation, surgical decompression, and phototherapy. These treatments result in significant symptom control in refractory cases. Physical therapy can be considered a first‐line choice or an alternative in refractory cases.ConclusionProcedural modalities are critical in the multidisciplinary approach to NP, especially for patients who are refractory to topical and oral treatments. Procedural modalities include a spectrum of options that can be applied based on the disease's symptoms and severity.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A systematic review of procedural modalities in the treatment of notalgia paresthetica

Nilforoushzadeh,

Ghane,

Heidari

et al. 2024

Skin Research and Technology

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“…Each patient in the study received several treatments and no adverse reactions were observed other than variable hyperpigmentation. Interestingly, no patients had a relapse of pruritus in 6 months after study completion 33. Cryolipolysis and light-based therapy for treatment of pruritus and paresthesia associated with notalgia paresthetica looks promising, but more research is warranted.…”

Section: Treatmentsmentioning

confidence: 99%

“…31 Light-based treatments have not been formally studied but a small 3-month observational study was performed by Fonda-Pascual et al on 11 White patients with notalgia paresthetica using a 308 nm excimer lamp. 33 Each patient in the study received several treatments and no adverse reactions were observed other than variable hyperpigmentation. Interestingly, no patients had a relapse of pruritus in 6 months after study completion.…”

Section: Cryolipolysis and Light-based Treatmentmentioning

confidence: 99%

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Notalgia paresthetica

Haney

2021

The Nurse Practitioner

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55-year-old woman states that she has itching to the right side of her mid-back for about the last 2 years. At fi rst, it did not bother her, but she has noticed it more in the past 6 months. The itch has worsened and is always in the same location. She reports that her husband didn't see anything on her back except a brownish "birth mark" that looked a lot like "a big freckle." You examine the patient and see a 5 cm fl at, irregularly shaped, slightly hyperpigmented patch with indistinct borders and no excoriations.

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Neurological Conditions Affecting the Skin

Affleck

2024

Rook's Textbook of Dermatology

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Effectiveness of 308‐nm excimer lamp in the treatment of notalgia paresthetica

Cited by 4 publications

References 10 publications

A systematic review of procedural modalities in the treatment of notalgia paresthetica

A systematic review of procedural modalities in the treatment of notalgia paresthetica

Notalgia paresthetica

Neurological Conditions Affecting the Skin

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