Effectiveness of 1-Visit and 2-Visit Endodontic Retreatment of Teeth with Persistent/Secondary Endodontic Infection: A Randomized Clinical Trial with 18 Months of Follow-up

Toia, Cássia Cestari; Khoury, Rayana Duarte; Corazza, Bruna Jordão Motta; Orozco, Esteban Isaí Flores; Valera, Márcia Carneiro

doi:10.1016/j.joen.2021.09.004

Cited by 17 publications

(21 citation statements)

References 41 publications

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“…Several studies confirmed that there is no difference in the outcome of the non-surgical retreatment cases between single and multiple visits. (14) .…”

Section: Discussionmentioning

confidence: 99%

Postoperative Pain evaluation after single visit nonsurgical retreatment using a Bio ceramic sealer

Ghobashy

Fakhr

2022

Egyptian Dental Journal

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Introduction/Objectives the aim of this study was to compare the difference in the postoperative pain when resin cements are used in comparison to bio ceramic cements in the obturation of root canals.Methods One hundred patients with permanent molar teeth requiring endodontic non-surgical retreatment were treated in this study. Preoperative assessment of the degree of the patient's pain was done using the visual analog scale. Fifty teeth were obturated with gutta percha using the epoxy resin-based sealer as the control group, and in the other fifty bio ceramic based cement was used. All teeth were prepared by the protaper next rotary files under copious irrigation with 30ml of 2.6 % sodium hypochlorite throughout the procedure. Obturation was done using the cold lateral compaction technique in the resin group and single cone technique in the bioceramic group. Postoperative pain assessment was done for each patient after six hours, twenty-four hours, four days and one week. ResultsThere was no statistically significant difference between pain scores regarding the postoperative pain between single cone bioceramic based obturation retreatments in comparison to the lateral compaction epoxy resin based obturation retreatments after 6, 24, 48 hours as well as one week. It was also found that There was no statistically significant difference between them in relation to age values and gender in the two groups.Conclusion with in the limitation of this study Single cone obturation with bioceramics can be used safely in single visit retreatment cases, when postoperative pain is being considered.

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“…Several studies confirmed that there is no difference in the outcome of the non-surgical retreatment cases between single and multiple visits. (14) .…”

Section: Discussionmentioning

confidence: 99%

Postoperative Pain evaluation after single visit nonsurgical retreatment using a Bio ceramic sealer

Ghobashy

Fakhr

2022

Egyptian Dental Journal

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“…While the retrospective study by Curtis et al concluded complete healing of only 41.2% for retreatments reviewed after 1-4 years (12) . Recently, Toia et al found that endodontic retreatment in one or 2 visits exhibited equally favorable periapical healing at 18 months (13) . On the other hand, the outcome of endodontic retreatment performed in single visit was investigated in 2 studies only, in which the overall success rate ranged from 84.9% to 90.9% (14,15) .…”

Section: Outcome Of Root Canal Retreatment Performed In Single Visit ...mentioning

confidence: 99%

Outcome of root canal retreatment performed in single visit. A cohort retrospective study.

Nasr

Harmoodi

Hussain

2022

Egyptian Dental Journal

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Introduction:The purpose of this retrospective study was to assess the outcome of endodontic retreatment performed in single visit.Methods: Retreatments were identified from the pool of patients treated in Dubai Health Authority (DHA) endodontic clinics between 2018 and 2019. The cases included were retreated in a single visit and followed up for at least 6 months. Data were retrieved from 139 cases and a template was created to collect demographic, procedural, clinical and radiographic information. Short term flare up and long term clinical and radiographic outcome were assessed, in addition to calculation of tooth survival. Moreover, the preoperative apical status and quality of root canal filling were studied as prognostic factors and were analyzed for their impact on the outcome.Results: Data from 127 patients, where 99 cases from women and 40 cases from men with a mean age of 46.5 years, showed that flare up occurred in 2.9% of the cases; a success rate of 92.1 % and survival rate of 94%. Statistical analysis did not discern an association between the quality of the previous root canal filling and outcome of retreatment. Conversely, there was an association between the presence of a preoperative apical periodontitis and outcome of treatment (p= 0.006) Conclusion: Single visit endodontic retreatment performed by specialists on asymptomatic teeth is a predictable therapy with a high incidence of healing and tooth retention.

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“…In the literature, LPS effect over macrophages, the predominant defense cell in periapical lesions have been studied to understand the production of inflammatory mediators 6 . Conversely, LTA effect is little explored 7 .…”

Section: Introductionmentioning

confidence: 99%

“…It promotes cell activation via TLR-2 receptor differently of LPS that promotes by signaling via TLR-4 receptor 9 . It can accumulate where E. faecalis resides as in dentin and periapical lesions 8 and has a role in pulp tissue destruction, therefore, it is necessary to understand its role in inflammations of dental pulp and periapical lesions 7 , 11 .…”

Section: Introductionmentioning

confidence: 99%

Detoxification of LTA by intracanal medication: analysis by macrophages proinflammatory cytokines production

Oliveira

Hatje

et al. 2022

Braz. Dent. J.

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The aim of this study was to evaluate in vitro the effect of calcium hydroxide [Ca(OH)2], 2% chlorhexidine gel (CHX) on macrophages (RAW 264.7) to produce pro-inflammatory cytokines and nitric oxide after pretreatment with lipoteichoic acid (LTA) of Enterococcus faecalis. Forty-eight human single-rooted teeth were instrumented with R25.08 (RECIPROC) and sterilized by gamma irradiation. LTA was inoculated in the root canal of each specimen for 96 hours. Specimens were instrumented with 40.06 and 50.05 (RECIPROC) and medicated with: I) Pyrogen-free saline solution (SS); II) 2% CHX gel; III) Ca(OH)2 + SS; or IV) Ca(OH)2 + CHX for 14 days. Three samples (S) were performed of the root canal of each specimen at: S1) immediately after instrumentation; S2) after Ethylenediaminetetraacetic acid (EDTA); S3) after intracanal medication removal. Subsequent quantification of cytokines (IL-1β, TNF-α, MIP-1α, IP-10, G-CSF and IL-6) by immunosorbent assay (ELISA) and nitric oxide by the Griess method was carried-out. Data were submitted to a normality test and then analyzed with one-way ANOVA and Tukey test with a significance level of 5% using GraphPad Prism 6. Ca(OH)2 + SS and Ca(OH)2 + CHX presented lower levels of TNF-α, TNF-α, IL-6, G-CSF and nitric oxide. Ca(OH)2 + SS was the most effective in reducing MIP-1α. CHX was effective in reducing IL-6 and G-CSF. Therefore, the combined intracanal medication of calcium hydroxide and chlorhexidine is effective in reducing the cytokines TNF-α, IL-1β, IL-6, G-CSF and nitric oxide.

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Effectiveness of 1-Visit and 2-Visit Endodontic Retreatment of Teeth with Persistent/Secondary Endodontic Infection: A Randomized Clinical Trial with 18 Months of Follow-up

Cited by 17 publications

References 41 publications

Postoperative Pain evaluation after single visit nonsurgical retreatment using a Bio ceramic sealer

Postoperative Pain evaluation after single visit nonsurgical retreatment using a Bio ceramic sealer

Outcome of root canal retreatment performed in single visit. A cohort retrospective study.

Detoxification of LTA by intracanal medication: analysis by macrophages proinflammatory cytokines production

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