“…We learned about Freudenthal et al (), Torres‐Lagares et al (), Babar et al (), Hita‐Iglesias et al (), Jesudasan et al (), Requena‐Calla and Funes‐Rumiche () applied drugs postoperatively before the patients’ second visit, and the drugs applied were not all the same. Only Jesudasan et al () mentioned about the wound healing, and the 0.2% CHX gel group showed better wound healing than control group. Finally, the mean difficulty of the mandibular third molar extractions was another confounding factor which resulting in variable damages to the surrounding tissues; however, we couldnot analysis this factor on account of different reference standards and ignoring it in some studies.…”