Effectiveness and safety of the hyaluronic acid INNORYOS 2.2% in patients with early to advanced knee osteoarthritis. A prospective non-interventional randomized clinical trial.
Lola Hofweber,
Simon von Stengel,
Jörg Nürnberger
et al.
Abstract:Introduction: We determined the effectiveness and safety of INNORYOS 2.2% hyaluronic acid (HA) containing 15mg of niacinamide on knee pain, stiffness and function in people with knee OA compared with an established agent. Further study objectives were to monitor side effects during the study period.
Methods: The 26-week prospective non-interventional open clinical trial tested on non-inferiority of INNORYOS 2.2% compared to an established HA product (Synvisc 0.8%, 2.0 ml). Briefly, 90 people with knee OA (Kell… Show more
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