Effectiveness and safety of the schedules of short and long term treatment for tuberculous meningoencephalitis at two hospitals of Lima - Peru

Morales, S.; Ramos, Willy; Vilchez, Rocio Yolanda Palomino; Pérez, José Luis Jiménez; Alvarado, Milliette

doi:10.1016/s2173-5808(11)70045-1

Cited by 3 publications

(3 citation statements)

References 14 publications

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“…Neuromeningeal tuberculosis represents a diagnostic and therapeutic emergency [1]. It associates a meningeal syndrome and an encephalitic syndrome.…”

Section: Introductionmentioning

confidence: 99%

Tuberculous Meningitis Complicated Without Deep Sylvian Cerebral Infarction: About an Immunocompetent Patient with HIV-AIDS

Tanoh,

Aka,

Yapo-Ehounoud

et al. 2024

AJPN

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Introduction: Neuromeningeal tuberculosis is the most common form of extra-pulmonary tuberculosis in developing countries. It is the most serious form of Mycobacterium tuberculosis infection. Vascular complications of tuberculous meningitis involve functional prognosis of patients. Observation: In our daily practice, we frequently encounter cases of cerebral infarction associated with neuromeningeal tuberculosis in the infectious etiological balance. We report the case of an HIV immunocompetent patient hospitalized for neuromeningeal tuberculosis complicated with ischemic stroke. It was a 39-year-old patient, right-handed, admitted to the Neurology department of University Hospital of Cocody in whom the diagnosis of neuromeningeal tuberculosis was retained. She received treatment for tuberculosis in emergency. On the seventh day of hospitalization, she suddenly presented with a massive motor deficit of the left hemibody. The MRI performed was compatible with meningoencephalitis associated with recent deep right Sylvan ischemia foci. The evolution was marked by partial recovery of the left hemiplegia, right retro-bulbar neuritis, and iatrogenic hepatic cytolysis. Comments: Tuberculous meningitis remains today one of the most serious neurological conditions involving the vital and functional prognosis of patients. Association of cerebral infarction and tuberculous meningitis is of variable occurrence. There are reported cases in which cerebral infarction is a complication of tuberculous meningitis. On the other hand, the discovery of tuberculous meningitis can be observed in the assessment of a cerebral infarction in young subjects. Tuberculous meningovascularitis remains a rare condition in immunocompetent patients for HIVAIDS. It results from arterial occlusion by thrombosing and obliterating endarteritis. It represents a medical emergency requiring starting anti-tuberculosis treatment. The evolution depends on the precocity of the diagnosis and the speed of treatment. Conclusion: The sudden appearance of a neurological deficit in à patient with tuberculous meningitis even under specific treatment should suggest an ischemic stroke, especially if the symptomatology respects an anatomo-functional vascular systematization.

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“…Neuromeningeal tuberculosis represents a diagnostic and therapeutic emergency [1]. It associates a meningeal syndrome and an encephalitic syndrome.…”

Section: Introductionmentioning

confidence: 99%

Tuberculous Meningitis Complicated Without Deep Sylvian Cerebral Infarction: About an Immunocompetent Patient with HIV-AIDS

Tanoh,

Aka,

Yapo-Ehounoud

et al. 2024

AJPN

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“…It associates a meningeal syndrome and an encephalitic syndrome. Tuberculous meningovasculitis represents one of the vascular complications responsible for ischemic stroke [1]. Tuberculous meningovascularitis is one of the vascular complications responsible for ischemic stroke.…”

Section: Introductionmentioning

confidence: 99%

Tuberculous Meningitis Complicated With Deep Sylvian Cerebral Infarction: About an Immunocompetent Patient With HIV-AIDS

Tanoh,

Aka,

Tanoh

et al. 2023

Preprint

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INTRODUCTION Neuromeningeal tuberculosis is the most common form of extra-pulmonary tuberculosis in developing countries. It is the most serious form of Mycobacterium tuberculosis infection. Vascular complications of tuberculous meningitis involve functional prognosis of patients.OBSERVATION In our daily practice, we frequently encounter cases of cerebral infarction associated with neuromeningeal tuberculosis in the infectious etiological balance. We report the case of an HIV immunocompetent patient hospitalized for neuromeningeal tuberculosis complicated with ischemic stroke. It was a 39-year-old patient, right-handed, admitted to the Neurology department of University Hospital of Cocody in whom the diagnosis of neuromeningeal tuberculosis was retained. She received treatment for tuberculosis in emergency. On the seventh day of hospitalization, she suddenly presented with a massive motor deficit of the left hemibody. The MRI performed was compatible with meningoencephalitis associated with recent deep right Sylvan ischemia foci. The evolution was marked by partial recovery of the left hemiplegia, right retro-bulbar neuritis, and iatrogenic hepatic cytolysis.COMMENTS Tuberculous meningitis remains today one of the most serious neurological conditions involving the vital and functional prognosis of patients. Association of cerebral infarction and tuberculous meningitis is of variable occurrence. There are reported cases in which cerebral infarction is a complication of tuberculous meningitis. On the other hand, the discovery of tuberculous meningitis can be observed in the assessment of a cerebral infarction in young subjects. Tuberculous meningovascularitis remains a rare condition in immunocompetent patients for HIV-AIDS. It results from arterial occlusion by thrombosing and obliterating endarteritis. It represents a medical emergency requiring starting anti-tuberculosis treatment. The evolution depends on the precocity of the diagnosis and the speed of treatment.CONCLUSION The sudden appearance of a neurological deficit in à patient with tuberculous meningitis even under specific treatment should suggest an ischemic stroke, especially if the symptomatology respects an anatomo-functional vascular systematization.

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“…La méningo-encéphalite tuberculeuse est une urgence diagnostique et thérapeutique. Elle associe au tableau méningé, une atteinte encéphalique avec des troubles de la conscience, une perturbation des fonctions supérieures et des signes de focalisation neurologique [ 1 ]. Les symptômes psychiatrique sont peu rapportés, et passent toujours au deuxième plan derrière les tableaux neurologique et infectieux.…”

Section: Introductionunclassified

Méningo-encéphalite tuberculeuse révélée par des troubles psychiatriques: à propos d’un cas

2017

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La méningo-encéphalite tuberculeuse est une pathologie assez fréquente dans les pays endémiques, et représente la forme la plus sévère de la tuberculose. L’échec thérapeutique est fréquent à cause du retard diagnostique. Ce retard est essentiellement dû au grand polymorphisme clinique et notamment en raison des formes trompeuses. Ce travail expose le cas clinique rare d’une méningite tuberculeuse se présentant sous forme d’un tableau psychiatrique typique au cours de sa phase prodromique.

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Effectiveness and safety of the schedules of short and long term treatment for tuberculous meningoencephalitis at two hospitals of Lima - Peru

Cited by 3 publications

References 14 publications

Tuberculous Meningitis Complicated Without Deep Sylvian Cerebral Infarction: About an Immunocompetent Patient with HIV-AIDS

Tuberculous Meningitis Complicated Without Deep Sylvian Cerebral Infarction: About an Immunocompetent Patient with HIV-AIDS

Tuberculous Meningitis Complicated With Deep Sylvian Cerebral Infarction: About an Immunocompetent Patient With HIV-AIDS

Méningo-encéphalite tuberculeuse révélée par des troubles psychiatriques: à propos d’un cas

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