Abstract:Background: One of the most significant changes needed for the transition to extrauterine life is the ductus arteriosus (DA) closure, which is located in the fetal circulatory system between both the aortic arch and the pulmonary artery. The extended length of patent DA (PDA), that further raises premature mortality and morbidity, impairs hemodynamics. The effectiveness and tolerability of oral ibuprofen administered at regular and high doses to treat PDA were examined in this research. Patients and Methods: T… Show more
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